Author results

2W4O
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CRYSTAL STRUCTURE OF HUMAN CAMK4 IN COMPLEX WITH 4-AMINO(SULFAMOYL- PHENYLAMINO)-TRIAZOLE-CARBOTHIOIC ACID (2,6-DIFLUORO-PHENYL)-AMIDE)
分子名称:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE
著者Muniz, J.R.C., Rellos, P., Gileadi, O., Fedorov, O., Filippakopoulos, P., Salah, E., Pike, A., Phillips, C., Niesen, F., Shrestha, L., Burgess-Brown, N., Bullock, A., Berridge, G., von Delft, F., Edwards, A.M., Bountra, C., Arrowsmith, C.H., Weigelt, J., Knapp, S.
登録日2008-11-28
公開日2009-01-20
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Crystal Structure of Human Camk4 in Complex with 4-Amino(Sulfamoyl-Phenylamino)-Triazole- Carbothioic Acid (2,6-Difluoro-Phenyl)-Amide)
To be Published
2WBI
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA DEHYDROGENASE 11
分子名称:ACYL-COA DEHYDROGENASE FAMILY MEMBER 11, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, ...
著者Muniz, J.R.C., Guo, K., Savitsky, P., Roos, A., Yue, W., Pilka, E., von Delft, F., Edwards, A.M., Bountra, C., Arrowsmith, C.H., Weigelt, J., Oppermann, U.
登録日2009-02-28
公開日2009-05-12
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Acyl-Coa Dehydrogenase 11
To be Published
2WNT
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CRYSTAL STRUCTURE OF THE HUMAN RIBOSOMAL PROTEIN S6 KINASE
分子名称:RIBOSOMAL PROTEIN S6 KINASE, SODIUM ION, CHLORIDE ION, ...
著者Muniz, J.R.C., Elkins, J.M., Wang, J., Ugochukwu, E., Salah, E., King, O., Picaud, S., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S.
登録日2009-07-20
公開日2009-08-25
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the Human Ribosomal Protein S6 Kinase
To be Published
2WZK
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STRUCTURE OF THE CUL5 N-TERMINAL DOMAIN AT 2.05A RESOLUTION.
分子名称:CULLIN-5, 1,2-ETHANEDIOL
著者Muniz, J.R.C., Ayinampudi, V., Zhang, Y., Babon, J.J., Chaikuad, A., Krojer, T., Pike, A.C.W., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bullock, A.N.
登録日2009-11-30
公開日2009-12-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
J.Mol.Biol., 425, 2013
2X4F
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THE CRYSTAL STRUCTURE OF THE HUMAN MYOSIN LIGHT CHAIN KINASE LOC340156.
分子名称:MYOSIN LIGHT CHAIN KINASE FAMILY MEMBER 4, 4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-dioxaziridin-3-ylphenyl)pyrimidin-2-amine, SULFATE ION, ...
著者Muniz, J.R.C., Mahajan, P., Rellos, P., Fedorov, O., Shrestha, B., Wang, J., Elkins, J.M., Daga, N., Cocking, R., Chaikuad, A., Krojer, T., Ugochukwu, E., Yue, W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Gileadi, O., Knapp, S.
登録日2010-01-29
公開日2010-02-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献The Crystal Structure of the Human Myosin Light Chain Kinase Loc340156
To be Published
2XIK
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STRUCTURE OF HUMAN YSK1 (YEAST SPS1-STE20-RELATED KINASE 1)
分子名称:SERINE/THREONINE PROTEIN KINASE 25, 1,2-ETHANEDIOL, 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE
著者Muniz, J.R.C., Rellos, P., Ugochukwu, E., Vollmar, M., Allerston, C., Chaikuad, A., Savitsky, P., Berridge, G., Brenner, B., Elkins, J.M., Daga, N., Gileadi, O., Mahajan, P., Shrestha, B., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S.
登録日2010-06-30
公開日2010-07-14
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure of Human Ysk1 (Yeast Sps1-Ste20-Related Kinase 1)
To be Published
2XIO
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STRUCTURE OF PUTATIVE DEOXYRIBONUCLEASE TATDN1 ISOFORM A
分子名称:PUTATIVE DEOXYRIBONUCLEASE TATDN1, SODIUM ION, NICKEL (II) ION, ...
著者Muniz, J.R.C., Cocking, R., Puranik, S., Krojer, T., Raynor, J., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Yue, W.W., Kavanagh, K.L., Oppermann, U.
登録日2010-06-30
公開日2010-07-14
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Structure of Putative Deoxyribonuclease Tatdn1 Isoform A
To be Published
2XSN
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CRYSTAL STRUCTURE OF HUMAN TYROSINE HYDROXYLASE CATALYTIC DOMAIN
分子名称:TYROSINE 3-MONOOXYGENASE, ZINC ION
著者Muniz, J.R.C., Cooper, C.D.O., Yue, W.W., Krysztofinska, E., von Delft, F., Knapp, S., Gileadi, O., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Kavanagh, K.L., Oppermann, U.
登録日2010-10-29
公開日2010-11-17
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Crystal Structure of Human Tyrosine Hydroxylase Catalytic Domain
To be Published
2XST
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CRYSTAL STRUCTURE OF THE HUMAN LIPOCALIN 15
分子名称:LIPOCALIN 15, 1,2-ETHANEDIOL
著者Muniz, J.R.C., Gileadi, C., Yue, W.W., Krojer, T., Ugochukwu, E., Phillips, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Kavanagh, K.L., Oppermann, U.
登録日2010-09-30
公開日2010-10-13
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal Structure of the Human Lipocalin 15
To be Published
2Y1H
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CRYSTAL STRUCTURE OF THE HUMAN TATD-DOMAIN PROTEIN 3 (TATDN3)
分子名称:PUTATIVE DEOXYRIBONUCLEASE TATDN3, ZINC ION, PHOSPHATE ION, ...
著者Muniz, J.R.C., Puranik, S., Krojer, T., Yue, W.W., Ugochukwu, E., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Kavanagh, K.L., Oppermann, U.
登録日2010-12-08
公開日2010-12-29
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the Human Tatd-Domain Protein 3 (Tatdn3)
To be Published
2Y7J
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STRUCTURE OF HUMAN PHOSPHORYLASE KINASE, GAMMA 2
分子名称:PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
著者Muniz, J.R.C., Shrestha, A., Savitsky, P., Wang, J., Rellos, P., Fedorov, O., Burgess-Brown, N., Brenner, B., Berridge, G., Elkins, J.M., Krojer, T., Vollmar, M., Che, K.H., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S.
登録日2011-01-31
公開日2011-02-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Human Phosphorylase Kinase, Gamma 2
To be Published
2YL2
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CRYSTAL STRUCTURE OF HUMAN ACETYL-COA CARBOXYLASE 1, BIOTIN CARBOXYLASE (BC) DOMAIN
分子名称:ACETYL-COA CARBOXYLASE 1
著者Muniz, J.R.C., Froese, D.S., Krysztofinska, E., Vollmar, M., Beltrami, A., Krojer, T., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Yue, W.W., Oppermann, U.
登録日2011-05-31
公開日2011-06-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Human Acetyl-Coa Carboxylase 1, Biotin Carboxylase (Bc) Domain
To be Published
3Q2F
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN BAZ2B IN COMPLEX WITH A TRIAZOLO LIGAND
分子名称:Bromodomain adjacent to zinc finger domain protein 2B, 4-{4-[3-(1H-imidazol-1-yl)propyl]-5-methyl-4H-1,2,4-triazol-3-yl}-1-methyl-1H-pyrazol-5-amine, 1,2-ETHANEDIOL
著者Muniz, J.R.C., Filippakopoulos, P., Picaud, S., Felletar, I., Keates, T., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2010-12-20
公開日2011-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand
TO BE PUBLISHED
3ZKJ
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CRYSTAL STRUCTURE OF ANKYRIN REPEAT AND SOCS BOX-CONTAINING PROTEIN 9 (ASB9) IN COMPLEX WITH ELONGINB AND ELONGINC
分子名称:ANKYRIN REPEAT AND SOCS BOX PROTEIN 9, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, ...
著者Muniz, J.R.C., Guo, K., Zhang, Y., Ayinampudi, V., Savitsky, P., Keates, T., Filippakopoulos, P., Vollmar, M., Yue, W.W., Krojer, T., Ugochukwu, E., von Delft, F., Knapp, S., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N.
登録日2013-01-23
公開日2013-01-30
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
J.Mol.Biol., 425, 2013
3ZW5
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CRYSTAL STRUCTURE OF THE HUMAN GLYOXALASE DOMAIN-CONTAINING PROTEIN 5
分子名称:GLYOXALASE DOMAIN-CONTAINING PROTEIN 5, SULFATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Muniz, J.R.C., Kiyani, W., Froese, S., Vollmar, M., von Delft, F., Burgess-Brown, N., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Yue, W.W.
登録日2011-07-28
公開日2011-08-10
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the Human Glyoxalase Domain-Containing Protein 5
To be Published
3ZYQ
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CRYSTAL STRUCTURE OF THE TANDEM VHS AND FYVE DOMAINS OF HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE (HGS-HRS) AT 1.48 A RESOLUTION
分子名称:HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE, ZINC ION, SULFATE ION, ...
著者Muniz, J.R.C., Ayinampudi, V., Shrestha, L., Krojer, T., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bullock, A.
登録日2011-08-24
公開日2011-09-07
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal Structure of the Tandem Vhs and Fyve Domains of Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) at 1.48 A Resolution
To be Published
4A60
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CRYSTAL STRUCTURE OF HUMAN TESTIS-SPECIFIC FATTY ACID BINDING PROTEIN 9 (FABP9)
分子名称:FATTY ACID-BINDING PROTEIN 9 TESTIS LIPID-BINDING PROTEIN, TLBP, TESTIS-TYPE FATTY ACID-BINDING PROTEIN, ...
著者Muniz, J.R.C., Kiyani, W., Shrestha, L., Froese, D.S., Krojer, T., Vollmar, M., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., von Delft, F., Yue, W.W.
登録日2011-10-31
公開日2011-11-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献The Crystal Structure of the Human Fabp9A
To be Published
4A9Z
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CRYSTAL STRUCTURE OF HUMAN P63 TETRAMERIZATION DOMAIN
分子名称:TUMOR PROTEIN 63, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
著者Muniz, J.R.C., Coutandin, D., Salah, E., Chaikuad, A., Vollmar, M., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Dotsch, V., von Delft, F., Knapp, S.
登録日2011-11-30
公開日2011-12-07
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Crystal Structure of Human P63 Tetramerization Domain
To be Published
2W7R
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STRUCTURE OF THE PDZ DOMAIN OF HUMAN MICROTUBULE ASSOCIATED SERINE- THREONINE KINASE 4
分子名称:MICROTUBULE-ASSOCIATED SERINE/THREONINE-PROTEIN KINASE 4, PHOSPHATE ION
著者Muniz, J.R.C., Elkins, J., Wang, J., Savitzky, P., Roos, A., Salah, E., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S.
登録日2008-12-24
公開日2009-05-12
最終更新日2015-01-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Unusual Binding Interactions in Pdz Domain Crystal Structures Help Explain Binding Mechanisms.
Protein Sci., 19, 2010
2WWW
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CRYSTAL STRUCTURE OF METHYLMALONIC ACIDEMIA TYPE A PROTEIN
分子名称:METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL, NONAETHYLENE GLYCOL, ...
著者Muniz, J.R.C., Gileadi, C., Froese, D.S., Yue, W.W., Pike, A.C.W., von Delft, F., Kochan, G., Sethi, R., Chaikuad, A., Pilka, E., Picaud, S., Phillips, C., Guo, K., Krysztofinska, E., Bray, J., Burgess-Brown, N., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., Gravel, R.A., Kavanagh, K.L., Oppermann, U.
登録日2009-10-30
公開日2009-11-17
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.
J.Biol.Chem., 285, 2010
2X64
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GLUTATHIONE-S-TRANSFERASE FROM XYLELLA FASTIDIOSA
分子名称:GLUTATHIONE-S-TRANSFERASE, CHLORIDE ION, GLUTATHIONE
著者Muniz, J.R.C., Rodrigues, N.C., Bleicher, L., Travensolo, R.F., Garcia, W.
登録日2010-02-14
公開日2010-03-02
最終更新日2011-12-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Biophysical Characterization of the Recombinant Glutathione-S-Transferase from Xylella
To be Published
2YDX
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CRYSTAL STRUCTURE OF HUMAN S-ADENOSYLMETHIONINE SYNTHETASE 2, BETA SUBUNIT
分子名称:METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA, RESVERATROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Muniz, J.R.C., Shafqat, N., Pike, A.C.W., Yue, W.W., Vollmar, M., Papagriogriou, V., Roos, A., Gileadi, O., von Delft, F., Kavanagh, K.L., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U.
登録日2011-03-25
公開日2011-04-27
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insight Into S-Adenosylmethionine Biosynthesis from the Crystal Structures of the Human Methionine Adenosyltransferase Catalytic and Regulatory Subunits.
Biochem.J., 452, 2013
4UOJ
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STRUCTURE OF FUNGAL BETA-MANNOSIDASE (GH2) FROM TRICHODERMA HARZIANUM
分子名称:BETA-MANNOSIDASE GH2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Muniz, J.R.C., Aparicio, R., Santos, J.C., Nascimento, A.S., Golubev, A.M., Polikarpov, I.
登録日2014-06-04
公開日2014-07-09
最終更新日2014-10-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insights Into the Structure and Function of Fungal Beta-Mannosidases from Glycoside Hydrolase Family 2 Based on Multiple Crystal Structures of the Trichoderma Harzianum Enzyme.
FEBS J., 281, 2014
2VNA
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STRUCTURE OF HUMAN ZINC-BINDING ALCOHOL DEHYDROGENASE 1 (ZADH1)
分子名称:PROSTAGLANDIN REDUCTASE 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Shafqat, N., Kavanagh, K., Pike, A.C.W., Muniz, J.R.C., Pilka, E., Roos, A.K., Picaud, S., Johansson, C., Smee, C., Fedorov, O., Kochan, G., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., von Delft, F., Opperman, U.
登録日2008-02-01
公開日2009-02-17
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure of Human Zinc-Binding Alcohol Dehydrogenase 1 (Zadh1)
To be Published
2W2J
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CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE RELATED PROTEIN VIII
分子名称:CARBONIC ANHYDRASE-RELATED PROTEIN, CHLORIDE ION, GLYCEROL, ...
著者Kramm, A., Muniz, J.R.C., Picaud, S.S., von Delft, F., Pilka, E.S., Yue, W.W., King, O.N.F., Kochan, G., Pike, A.C.W., Filippakopoulos, P., Arrowsmith, C., Wikstrom, M., Edwards, A., Bountra, C., Oppermann, U.
登録日2008-10-31
公開日2009-02-03
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Human Carbonic Anhydrase-Related Protein Viii Reveals the Basis for Catalytic Silencing.
Proteins, 76, 2009