Author results

2PSS
  • Download 2pss
  • View 2pss
Molmil generated image of 2pss
THE STRUCTURE OF PLASMODIUM FALCIPARUM SPERMIDINE SYNTHASE IN ITS APO-FORM
分子名称:Spermidine synthase, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, GLYCEROL, ...
著者Dufe, V.T., Qiu, W., Muller, I.B., Hui, R., Walter, R.D., Al-Karadaghi, S., Structural Genomics Consortium (SGC)
登録日2007-05-07
公開日2008-04-01
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
2PT6
  • Download 2pt6
  • View 2pt6
Molmil generated image of 2pt6
THE STRUCTURE OF PLASMODIUM FALCIPARUM SPERMIDINE SYNTHASE IN COMPLEX WITH DECARBOXYLATED S-ADENOSYLMETHIONINE
分子名称:Spermidine synthase, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ...
著者Dufe, V.T., Qiu, W., Muller, I.B., Hui, R., Walter, R.D., Al-Karadaghi, S., Structural Genomics Consortium (SGC)
登録日2007-05-08
公開日2008-04-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
2PT9
  • Download 2pt9
  • View 2pt9
Molmil generated image of 2pt9
THE STRUCTURE OF PLASMODIUM FALCIPARUM SPERMIDINE SYNTHASE IN COMPLEX WITH DECARBOXYLATED S-ADENOSYLMETHIONINE AND THE INHIBITOR CIS-4-METHYLCYCLOHEXYLAMINE (4MCHA)
分子名称:Spermidine synthase, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, cis-4-methylcyclohexanamine, ...
著者Dufe, V.T., Qiu, W., Muller, I.B., Hui, R., Walter, R.D., Al-Karadaghi, S., Structural Genomics Consortium (SGC)
登録日2007-05-08
公開日2008-04-01
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
3K7Y
  • Download 3k7y
  • View 3k7y
Molmil generated image of 3k7y
ASPARTATE AMINOTRANSFERASE OF PLASMODIUM FALCIPARUM
分子名称:Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ACETATE ION
著者Groves, M.R., Jordanova, R., Jain, R., Wrenger, C., Muller, I.B.
登録日2009-10-13
公開日2010-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Specific Inhibition of the Aspartate Aminotransferase of Plasmodium falciparum.
J.Mol.Biol., 405, 2011
2OB2
  • Download 2ob2
  • View 2ob2
Molmil generated image of 2ob2
PPM1 IN THE ABSENCE OF 1,8-ANS (CF 1JD)
分子名称:Leucine carboxyl methyltransferase 1, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Groves, M.R., Mueller, I.B., Kreplin, X., Mueller-Dieckmann, J.
登録日2006-12-18
公開日2007-01-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A method for the general identification of protein crystals in crystallization experiments using a noncovalent fluorescent dye.
Acta Crystallogr.,Sect.D, 63, 2007
2OB1
  • Download 2ob1
  • View 2ob1
Molmil generated image of 2ob1
PPM1 WITH 1,8-ANS
分子名称:Leucine carboxyl methyltransferase 1, PHOSPHATE ION
著者Groves, M.R.
登録日2006-12-18
公開日2007-01-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A method for the general identification of protein crystals in crystallization experiments using a noncovalent fluorescent dye.
Acta Crystallogr.,Sect.D, 63, 2007
5NFR
  • Download 5nfr
  • View 5nfr
Molmil generated image of 5nfr
CRYSTAL STRUCTURE OF MALATE DEHYDROGENASE FROM PLASMODIUM FALCIPARUM (PFMDH)
分子名称:Malate dehydrogenase, CITRIC ACID
著者Lunev, S., Romero, A.R., Batista, F.A., Wrenger, C., Groves, M.R.
登録日2017-03-15
公開日2018-01-31
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro.
PLoS ONE, 13, 2018
2I7C
  • Download 2i7c
  • View 2i7c
Molmil generated image of 2i7c
THE CRYSTAL STRUCTURE OF SPERMIDINE SYNTHASE FROM P. FALCIPARUM IN COMPLEX WITH ADODATO
分子名称:Spermidine synthase, S-ADENOSYL-1,8-DIAMINO-3-THIOOCTANE, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ...
著者Qiu, W., Dong, A., Ren, H., Wu, H., Wasney, G., Vedadi, M., Lew, J., Kozieradski, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Plotnikov, A.N., Bochkarev, A., Hui, R., Structural Genomics Consortium (SGC)
登録日2006-08-30
公開日2006-09-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
3RIE
  • Download 3rie
  • View 3rie
Molmil generated image of 3rie
THE STRUCTURE OF PLASMODIUM FALCIPARUM SPERMIDINE SYNTHASE IN COMPLEX WITH 5'-METHYLTHIOADENOSINE AND N-(3-AMINOPROPYL)-TRANS-CYCLOHEXANE-1,4-DIAMINE
分子名称:Spermidine synthase, 5'-DEOXY-5'-METHYLTHIOADENOSINE, trans-N-(3-aminopropyl)cyclohexane-1,4-diamine, ...
著者Williams, M., Sprenger, J., Persson, L., Louw, A.I., Birkholtz, L., Al-Karadaghi, S.
登録日2011-04-13
公開日2012-04-25
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail.
Malar J, 14, 2015
5CGA
  • Download 5cga
  • View 5cga
Molmil generated image of 5cga
STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SUBSTRATE ANALOG 2-(1,3,5-TRIMETHYL-1H-PYRAZOLE-4-YL)ETHANOL
分子名称:Hydroxyethylthiazole kinase, 2-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethanol, MAGNESIUM ION
著者Kuenz, M., Drebes, J., Windshuegel, B., Cang, H., Wrenger, C., Betzel, C.
登録日2015-07-09
公開日2016-03-23
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016
5CGE
  • Download 5cge
  • View 5cge
Molmil generated image of 5cge
STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH SUBSTRATE ANALOG 2-(2-METHYL-1H-IMIDAZOLE-1-YL)ETHANOL
分子名称:Hydroxyethylthiazole kinase, 2-(2-methyl-1H-imidazol-1-yl)ethanol, MAGNESIUM ION
著者Kuenz, M., Drebes, J., Windshuegel, B., Cang, H., Wrenger, C., Betzel, C.
登録日2015-07-09
公開日2016-03-23
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016
5CM5
  • Download 5cm5
  • View 5cm5
Molmil generated image of 5cm5
STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS
分子名称:Hydroxyethylthiazole kinase
著者Drebes, J., Kuenz, M., Eberle, R.J., Oberthuer, D., Cang, H., Wrenger, C., Betzel, C.
登録日2015-07-16
公開日2016-03-23
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016
5COJ
  • Download 5coj
  • View 5coj
Molmil generated image of 5coj
STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE THIM FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH NATIVE SUBSTRATE 2-(4-METHYL-1,3-THIAZOL-5-YL)ETHANOL.
分子名称:Hydroxyethylthiazole kinase, 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, MAGNESIUM ION
著者Drebes, J., Kuenz, M., Eberle, R.J., Oberthuer, D., Cang, H., Wrenger, C., Betzel, C.
登録日2015-07-20
公開日2016-03-23
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016