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1KBE
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BU of 1kbe by Molmil
Solution structure of the cysteine-rich C1 domain of Kinase Suppressor of Ras
Descriptor: Kinase Suppressor of Ras, ZINC ION
Authors:Zhou, M, Horita, D.A, Waugh, D.S, Byrd, R.A, Morrison, D.K.
Deposit date:2001-11-06
Release date:2002-01-23
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR).
J.Mol.Biol., 315, 2002
1KBF
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BU of 1kbf by Molmil
Solution Structure of the Cysteine-Rich C1 Domain of Kinase Suppressor of Ras
Descriptor: Kinase suppressor of Ras 1, ZINC ION
Authors:Zhou, M, Horita, D.A, Waugh, D.S, Byrd, R.A, Morrison, D.K.
Deposit date:2001-11-06
Release date:2002-01-23
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR).
J.Mol.Biol., 315, 2002
7MFD
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BU of 7mfd by Molmil
Autoinhibited BRAF:(14-3-3)2:MEK complex with the BRAF RBD resolved
Descriptor: 14-3-3 protein zeta/delta, Dual specificity mitogen-activated protein kinase kinase 1, N-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2H-chromen-3-yl]methyl}pyridin-2-yl)-N'-methylsulfuric diamide, ...
Authors:Martinez Fiesco, J.A, Ping, Z, Durrant, D.E, Morrison, D.K.
Deposit date:2021-04-09
Release date:2022-01-26
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding.
Nat Commun, 13, 2022
7MFF
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BU of 7mff by Molmil
Dimeric (BRAF)2:(14-3-3)2 complex bound to SB590885 Inhibitor
Descriptor: (1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME, 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf
Authors:Martinez Fiesco, J.A, Ping, Z, Durrant, D.E, Morrison, D.K.
Deposit date:2021-04-09
Release date:2022-01-26
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding.
Nat Commun, 13, 2022
7MFE
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BU of 7mfe by Molmil
Autoinhibited BRAF:(14-3-3)2 complex with the BRAF RBD resolved
Descriptor: 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf, ZINC ION
Authors:Martinez Fiesco, J.A, Ping, Z, Durrant, D.E, Morrison, D.K.
Deposit date:2021-04-09
Release date:2022-01-26
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding.
Nat Commun, 13, 2022
5WI4
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BU of 5wi4 by Molmil
CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH ARHGEF2
Descriptor: Dynein light chain Tctex-type 1,Rho guanine nucleotide exchange factor 2, SULFATE ION
Authors:Balan, M, Ishiyama, N, Marshall, C.B, Ikura, M.
Deposit date:2017-07-18
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.
Sci Signal, 10, 2017
7JIH
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BU of 7jih by Molmil
HRAS A59E GppNHp
Descriptor: GLYCEROL, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Haigis, K.M.
Deposit date:2020-07-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.989 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7JIF
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BU of 7jif by Molmil
HRAS A59T GppNHp
Descriptor: GLYCEROL, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Haigis, K.M.
Deposit date:2020-07-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.757 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7JII
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BU of 7jii by Molmil
HRAS A59E GDP
Descriptor: CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Johnson, C.W, Haigis, K.M.
Deposit date:2020-07-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.532 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7JIG
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BU of 7jig by Molmil
HRAS A59T GppNHp crystal 2
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Johnson, C.W, Haigis, K.M.
Deposit date:2020-07-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.322 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
2LPE
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BU of 2lpe by Molmil
Solution NMR Structure of the KSR1 CA1-CA1a domain
Descriptor: Kinase suppressor of Ras 1
Authors:Koveal, D, Peti, W, Page, R.
Deposit date:2012-02-11
Release date:2012-12-26
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A CC-SAM, for Coiled Coil Sterile a Motif, Domain Targets the Scaffold KSR-1 to Specific Sites in the Plasma Membrane
SCI.SIGNAL., 5, 2012
7KMR
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BU of 7kmr by Molmil
Crystal structure analysis of human KRAS mutant
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas
Authors:Seo, H.-S, Dhe-Paganon, S.
Deposit date:2020-11-03
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022

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