Author results

2BM2
  • Download 2bm2
  • View 2bm2
Molmil generated image of 2bm2
HUMAN BETA-II TRYPTASE IN COMPLEX WITH 4-(3-AMINOMETHYL-PHENYL)- PIPERIDIN-1-YL-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE
Descriptor:HUMAN BETA2 TRYPTASE, 1-[3-(1-{[5-(2-PHENYLETHYL)PYRIDIN-3-YL]CARBONYL}PIPERIDIN-4-YL)PHENYL]METHANAMINE
Authors:Maignan, S., Guilloteau, J.-P., Dupuy, A., Levell, J., Astles, P., Eastwood, P., Cairns, J., Houille, O., Aldous, S., Merriman, G., Whiteley, B., Pribish, J., Czekaj, M., Liang, G., Davidson, J., Harrison, T., Morley, A., Watson, S., Fenton, G., Mccarthy, C., Romano, J., Mathew, R., Engers, D., Gardyan, M., Sides, K., Kwong, J., Tsay, J., Rebello, S., Shen, L., Wang, J., Luo, Y., Giardino, O., Lim, H.-K., Smith, K., Pauls, H.
Deposit date:2005-03-09
Release date:2005-03-22
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure Based Design of 4-(3-Aminomethylphenyl) Piperidinyl-1-Amides: Novel, Potent, Selective, and Orally Bioavailable Inhibitors of Bii Tryptase
Bioorg.Med.Chem., 13, 2005
3HWN
  • Download 3hwn
  • View 3hwn
Molmil generated image of 3hwn
CATHEPSIN L WITH AZ13010160
Descriptor:Cathepsin L1, Nalpha-[(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)carbonyl]-N-[(2E)-2-iminoethyl]-3-{5-[(Z)-iminomethyl]-1,3,4-oxadiazol-2-yl}-L-phenylalaninamide
Authors:Kenny, P., Morley, A.
Deposit date:2009-06-18
Release date:2009-09-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Design of selective Cathepsin inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
2XYA
  • Download 2xya
  • View 2xya
Molmil generated image of 2xya
NON-COVALENT INHIBTORS OF RHINOVIRUS 3C PROTEASE.
Descriptor:PICORNAIN 3C, 2-PHENYLQUINOLIN-4-OL
Authors:Petersen, J., Edman, K., Edfeldt, F., Johansson, C.
Deposit date:2010-11-16
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Non-Covalent Inhibitors of Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 21, 2011