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1NYH
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CRYSTAL STRUCTURE OF THE COILED-COIL DIMERIZATION MOTIF OF SIR4
Descriptor:Regulatory protein SIR4
Authors:Chang, J.F., Hall, B.E., Tanny, J.C., Moazed, D., Filman, D., Ellenberger, T.
Deposit date:2003-02-12
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the Coiled-coil Dimerization Motif of Sir4 and Its Interaction With Sir3
Structure, 11, 2003
4JJN
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CRYSTAL STRUCTURE OF HETEROCHROMATIN PROTEIN SIR3 IN COMPLEX WITH A SILENCED YEAST NUCLEOSOME
Descriptor:Histone H3, Histone H4, Histone H2A.2, ...
Authors:Wang, F., Li, G., Mohammed, A., Lu, C., Currie, M., Johnson, A., Moazed, D.
Deposit date:2013-03-08
Release date:2013-05-15
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA.
Proc.Natl.Acad.Sci.USA, 110, 2013
6BOX
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STRUCTURE OF THE S. POMBE CLR4 CATALYTIC DOMAIN BOUND TO SAH
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-9 specific, ZINC ION, ...
Authors:Currie, M.A., Moazed, D.
Deposit date:2017-11-21
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.412 Å)
Cite:Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability.
Nature, 560, 2018
6BP4
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STRUCTURE OF THE S. POMBE CLR4 CATALYTIC DOMAIN BOUND TO SAM
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-9 specific, ZINC ION, ...
Authors:Currie, M.A., Moazed, D.
Deposit date:2017-11-21
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7701 Å)
Cite:Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability.
Nature, 560, 2018
2HJH
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CRYSTAL STRUCTURE OF THE SIR2 DEACETYLASE
Descriptor:NAD-dependent histone deacetylase SIR2, ZINC ION, (2R,3R,4S,5R)-5-({[(R)-{[(R)-{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL ACETATE, ...
Authors:Hall, B.E., Ellenberger, T.E.
Deposit date:2006-06-30
Release date:2008-04-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Autoregulation of the yeast Sir2 deacetylase by reaction and trapping of a pseudosubstrate motif in the active site
To be Published
3D1B
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TETRAGONAL CRYSTAL STRUCTURE OF TAS3 C-TERMINAL ALPHA MOTIF
Descriptor:RNA-induced transcriptional silencing complex protein tas3
Authors:Li, H., Patel, D.J.
Deposit date:2008-05-05
Release date:2009-04-21
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3D1D
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HEXAGONAL CRYSTAL STRUCTURE OF TAS3 C-TERMINAL ALPHA MOTIF
Descriptor:RNA-induced transcriptional silencing complex protein tas3
Authors:Li, H., Patel, D.J.
Deposit date:2008-05-05
Release date:2009-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009