4CDO
| Crystal structure of PQBP1 bound to spliceosomal U5-15kD | Descriptor: | THIOREDOXIN-LIKE PROTEIN 4A, POLYGLUTAMINE-BINDING PROTEIN | Authors: | Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Nabeshima, Y, Okazawa, H. | Deposit date: | 2013-11-05 | Release date: | 2014-04-30 | Last modified: | 2014-05-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd. Nat.Commun., 5, 2014
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4BWS
| Crystal structure of the heterotrimer of PQBP1, U5-15kD and U5-52kD. | Descriptor: | CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2, POLYGLUTAMINE-BINDING PROTEIN 1, THIOREDOXIN-LIKE PROTEIN 4A | Authors: | Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Morimoto, T, Nabeshima, Y, Okazawa, H. | Deposit date: | 2013-07-04 | Release date: | 2014-04-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd. Nat.Commun., 5, 2014
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4BWQ
| Crystal structure of U5-15kD in a complex with PQBP1 | Descriptor: | POLYGLUTAMINE-BINDING PROTEIN 1, THIOREDOXIN-LIKE PROTEIN 4A | Authors: | Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Morimoto, T, Nabeshima, Y, Okazawa, H. | Deposit date: | 2013-07-04 | Release date: | 2014-04-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd. Nat.Commun., 5, 2014
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1WO1
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1WO0
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7W9Q
| Crystal structure of V30M-TTR in complex with naringenin derivative-14 | Descriptor: | (2~{R})-2-(3-chloranyl-4-oxidanyl-phenyl)-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, CALCIUM ION, Transthyretin | Authors: | Katayama, W, Shimane, A, Nabeshima, Y, Yokoyama, T, Mizuguchi, M. | Deposit date: | 2021-12-10 | Release date: | 2022-12-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis. J.Med.Chem., 65, 2022
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7W9R
| Crystal structure of V30M-TTR in complex with naringenin derivative-18 | Descriptor: | (2~{R})-2-[3,5-bis(chloranyl)-4-oxidanyl-phenyl]-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, Transthyretin | Authors: | Katayama, W, Shimane, A, Nabeshima, Y, Yokoyama, T, Mizuguchi, M. | Deposit date: | 2021-12-10 | Release date: | 2022-12-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis. J.Med.Chem., 65, 2022
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8I75
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8I76
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8I74
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6KGB
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7WL6
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4PWG
| Crystal structure of V30M mutant human transthyretin complexed with caffeic acid ethyl ester | Descriptor: | CALCIUM ION, Transthyretin, ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate | Authors: | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | Deposit date: | 2014-03-20 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin J.Med.Chem., 57, 2014
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4PWK
| Crystal structure of V30M mutant human transthyretin complexed with dihydroguaiaretic acid | Descriptor: | 4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]bis(2-methoxyphenol), Transthyretin | Authors: | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | Deposit date: | 2014-03-20 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin J.Med.Chem., 57, 2014
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4QRF
| Crystal structure of V30M mutant human transthyretin complexed with caffeic acid phenethyl ester | Descriptor: | 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, Transthyretin | Authors: | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | Deposit date: | 2014-06-30 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin J.Med.Chem., 57, 2014
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2MDB
| Tachyplesin I in the presence of lipopolysaccharide | Descriptor: | Tachyplesin-1 | Authors: | Kushibiki, T, Kamiya, M, Aizawa, T, Kumaki, Y, Kikukawa, T, Mizuguchi, M, Demura, M, Kawabata, S.I, Kawano, K. | Deposit date: | 2013-09-09 | Release date: | 2014-02-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Interaction between tachyplesin I, an antimicrobial peptide derived from horseshoe crab, and lipopolysaccharide. Biochim.Biophys.Acta, 1844, 2014
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2RTV
| Tachyplesin I in water | Descriptor: | Tachyplesin-1 | Authors: | Kushibiki, T, Kamiya, M, Aizawa, T, Kumaki, Y, Kikukawa, T, Mizuguchi, M, Demura, M, Kawabata, S.I, Kawano, K. | Deposit date: | 2013-09-19 | Release date: | 2014-02-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Interaction between tachyplesin I, an antimicrobial peptide derived from horseshoe crab, and lipopolysaccharide. Biochim.Biophys.Acta, 1844, 2014
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4Y9B
| Crystal structure of V30M mutated transthyretin in complex with alpha-mangostin | Descriptor: | 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, CALCIUM ION, CHLORIDE ION, ... | Authors: | Yokoyama, T, Mizuguchi, M. | Deposit date: | 2015-02-17 | Release date: | 2015-09-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor Sci Rep, 5, 2015
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4Y9F
| Crystal structure of V30M mutated transthyretin with bromide in complex with gamma-mangostin | Descriptor: | 1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, BROMIDE ION, Transthyretin | Authors: | Yokoyama, T, Mizuguchi, M. | Deposit date: | 2015-02-17 | Release date: | 2015-09-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor Sci Rep, 5, 2015
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4Y9E
| Crystal structure of V30M mutated transthyretin in complex with gamma-mangostin | Descriptor: | 1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, CHLORIDE ION, Transthyretin | Authors: | Yokoyama, T, Mizuguchi, M. | Deposit date: | 2015-02-17 | Release date: | 2015-09-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor Sci Rep, 5, 2015
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4Y9C
| Crystal structure of V30M mutated transthyretin with bromide in complex with alpha-mangostin | Descriptor: | 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, BROMIDE ION, Transthyretin | Authors: | Yokoyama, T, Mizuguchi, M. | Deposit date: | 2015-02-17 | Release date: | 2015-09-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor Sci Rep, 5, 2015
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4Y9G
| Crystal structure of V30M mutated transthyretin in complex with 3-isomangostin | Descriptor: | 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one, Transthyretin | Authors: | Yokoyama, T, Mizuguchi, M. | Deposit date: | 2015-02-17 | Release date: | 2015-09-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor Sci Rep, 5, 2015
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3A5P
| Crystal structure of hemagglutinin | Descriptor: | Haemagglutinin I | Authors: | Watanabe, N, Sakai, N, Nakamura, T, Nabeshima, Y, Kouno, T, Mizuguchi, M, Kawano, K. | Deposit date: | 2009-08-10 | Release date: | 2010-08-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | The Structure of Physarum polycephalum hemagglutinin I suggests a minimal carbohydrate recognition domain of legume lectin fold J.Mol.Biol., 405, 2011
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7CCU
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7CCV
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