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7Z38
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BU of 7z38 by Molmil
Structure of the RAF1-HSP90-CDC37 complex (RHC-I)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
Authors:Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G.
Deposit date:2022-03-01
Release date:2022-09-14
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.
Mol.Cell, 82, 2022
7Z37
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BU of 7z37 by Molmil
Structure of the RAF1-HSP90-CDC37 complex (RHC-II)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
Authors:Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G.
Deposit date:2022-03-01
Release date:2022-09-14
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.
Mol.Cell, 82, 2022
6GTC
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BU of 6gtc by Molmil
Transition state structure of Cpf1(Cas12a) I1 conformation
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*G)-3'), DNA (5'-D(P*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ...
Authors:Mesa, P, Montoya, G.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
6GTG
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BU of 6gtg by Molmil
Transition state structure of Cpf1(Cas12a) I4 conformation
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (32-MER), DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*GP*T)-3'), ...
Authors:Mesa, P, Montoya, G, Stella, S.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
5JNO
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BU of 5jno by Molmil
Crystal structure of the BD1-NTPR complex from BEND3 and PICH
Descriptor: BEN domain-containing protein 3, DNA excision repair protein ERCC-6-like, GLYCEROL
Authors:Pitchai, G, Mesa, P, Hickson, I.D, Montoya, G.
Deposit date:2016-04-30
Release date:2017-09-13
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the BD1-NTPR complex from BEND3 and PICH
To Be Published
1NO1
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BU of 1no1 by Molmil
Structure of truncated variant of B.subtilis SPP1 phage G39P helicase loader/inhibitor protein
Descriptor: replisome organizer
Authors:Bailey, S, Sedelnikova, S.E, Mesa, P, Ayora, S, Waltho, J.P, Ashcroft, A.E, Baron, A.J, Alonso, J.C, Rafferty, J.B.
Deposit date:2003-01-15
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analysis of Bacillus subtilis SPP1 phage helicase loader protein G39P
J.Biol.Chem., 278, 2003
6GTE
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BU of 6gte by Molmil
Transient state structure of CRISPR-Cpf1 (Cas12a) I3 conformation
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*G)-3'), ...
Authors:Montoya, G, Mesa, P, Stella, S.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
6GTD
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BU of 6gtd by Molmil
Transient state structure of CRISPR-Cpf1 (Cas12a) I2 conformation
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*GP*T)-3'), DNA (5'-D(P*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ...
Authors:Montoya, G, Mesa, P.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
6GTF
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BU of 6gtf by Molmil
Transient state structure of CRISPR-Cpf1 (Cas12a) I5 conformation
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*A)-3'), ...
Authors:Montoya, G, Mesa, P, Stella, S.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
2XSM
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BU of 2xsm by Molmil
Crystal structure of the mammalian cytosolic chaperonin CCT in complex with tubulin
Descriptor: CCT
Authors:Munoz, I.G, Yebenes, H, Zhou, M, Mesa, P, Serna, M, Bragado-Nilsson, E, Beloso, A, Robinson, C.V, Valpuesta, J.M, Montoya, G.
Deposit date:2010-10-29
Release date:2010-12-15
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Crystal Structure of the Open Conformation of the Mammalian Chaperonin Cct in Complex with Tubulin.
Nat.Struct.Mol.Biol., 18, 2011
6DTD
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BU of 6dtd by Molmil
High-resolution crystal structure of Cas13b from Prevotella buccae
Descriptor: CHLORIDE ION, CITRIC ACID, RNA (37-MER), ...
Authors:Slaymaker, I.M.S, Zhang, F.Z.
Deposit date:2018-06-15
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage.
Cell Rep, 26, 2019
4B2T
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BU of 4b2t by Molmil
The crystal structures of the eukaryotic chaperonin CCT reveal its functional partitioning
Descriptor: T-COMPLEX PROTEIN 1 SUBUNIT ALPHA, T-COMPLEX PROTEIN 1 SUBUNIT BETA, T-COMPLEX PROTEIN 1 SUBUNIT DELTA, ...
Authors:Kalisman, N, Schroeder, G.F, Levitt, M.
Deposit date:2012-07-17
Release date:2013-03-20
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:The Crystal Structures of the Eukaryotic Chaperonin Cct Reveal its Functional Partitioning
Structure, 21, 2013

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