5EGM
| Development of a novel tricyclic class of potent and selective FIXa inhibitors | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-chloranyl-~{N}-[(7~{S})-2-methyl-7-phenyl-10-(1~{H}-1,2,3,4-tetrazol-5-yl)-8,9-dihydro-6~{H}-pyrido[1,2-a]indol-7-yl]-4-(1,2,4-triazol-4-yl)benzamide, Coagulation factor IX, ... | Authors: | Meng, D, Andre, P, Bateman, T.J, Berger, R, Chen, Y, Desai, K, Dewnani, S, Ellsworth, K, Feng, D, Geissler, W.M, Guo, L, Hruza, A, Jian, T, Li, H, Parker, D.L, Reichert, P, Sherer, E.C, Smith, C.J, Sonatore, L.M, Tschirret-Guth, R, Wu, J, Xu, J, Zhang, T, Campeau, L, Orr, R, Poirier, M, McCabe-Dunn, j, Araki, K, Nishimura, T, Sakurada, I, Hirabayashi, T, Wood, H.B. | Deposit date: | 2015-10-27 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.841 Å) | Cite: | Development of a novel tricyclic class of potent and selective FIXa inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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2LUT
| NMR solution structure of midkine-a | Descriptor: | Midkine-related growth factor | Authors: | Lim, J, Yang, D, Meng, D. | Deposit date: | 2012-06-21 | Release date: | 2013-05-01 | Method: | SOLUTION NMR | Cite: | Structural and Functional Characterization of Two Zebrafish Midkine Proteins Reveals Importance of the Conserved Hinge for Heparin Binding and Embryogenesis To be Published
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4X0V
| Structure of a GH5 family lichenase from Caldicellulosiruptor sp. F32 | Descriptor: | Beta-1,3-1,4-glucanase | Authors: | Meng, D, Liu, X, Wang, X, Li, F, Feng, Y. | Deposit date: | 2014-11-24 | Release date: | 2015-11-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.798 Å) | Cite: | Structural Insights into the Substrate Specificity of a Glycoside Hydrolase Family 5 Lichenase from Caldicellulosiruptor sp. F32 Biochem. J., 2017
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4ZAE
| Development of a novel class of potent and selective FIXa inhibitors | Descriptor: | 2,6-dichloro-N-[(2R)-2-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-phenylethyl]-4-(4H-1,2,4-triazol-4-yl)benzamide, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Coagulation factor IX, ... | Authors: | Hruza, A, Reichert, P. | Deposit date: | 2015-04-13 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Development of a novel class of potent and selective FIXa inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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2LUU
| NMR solution structure of midkine-b, mdkb | Descriptor: | Midkine-related growth factor Mdk2 | Authors: | Yang, D, Lim, J, Meng, D. | Deposit date: | 2012-06-21 | Release date: | 2013-05-01 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesis. Biochem.J., 451, 2013
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