6GVT
 
 | | Hybrid structure of the pRN1 helix bundle domain in complex with DNA and 2 ATP molecules | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*GP*TP*GP*CP*TP*CP*A)-3'), MAGNESIUM ION, ... | | Authors: | Boudet, J, Wiegand, T, Meier, B.H, Lipps, G, Allain, F.H.-T. | | Deposit date: | 2018-06-21 | | Release date: | 2018-12-26 | | Last modified: | 2019-08-21 | | Method: | SOLID-STATE NMR, SOLUTION NMR | | Cite: | A Small Helical Bundle Prepares Primer Synthesis by Binding Two Nucleotides that Enhance Sequence-Specific Recognition of the DNA Template.
Cell, 176, 2019
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2KJ3
 | | High-resolution structure of the HET-s(218-289) prion in its amyloid form obtained by solid-state NMR | | Descriptor: | Small s protein | | Authors: | Van Melckebeke, H, Wasmer, C, Lange, A, AB, E, Loquet, A, Meier, B.H. | | Deposit date: | 2009-05-20 | | Release date: | 2010-06-02 | | Last modified: | 2011-07-13 | | Method: | SOLID-STATE NMR | | Cite: | Atomic-Resolution Three-Dimensional Structure of HET-s(218-289) Amyloid Fibrils by Solid-State NMR Spectroscopy
J.Am.Chem.Soc., 132, 2010
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2MUS
 | | HADDOCK calculated model of LIN5001 bound to the HET-s amyloid | | Descriptor: | 3''',4'-bis(carboxymethyl)-2,2':5',2'':5'',2''':5''',2''''-quinquethiophene-5,5''''-dicarboxylic acid, Heterokaryon incompatibility protein s | | Authors: | Hermann, U.S, Schuetz, A.K, Shirani, H, Saban, D, Nuvolone, M, Huang, D.H, Li, B, Ballmer, B, Aslund, A.K.O, Mason, J.J, Rushing, E, Budka, H, Hammarstrom, P, Bockmann, A, Caflisch, A, Meier, B.H, Nilsson, P.K.R, Hornemann, S, Aguzzi, A. | | Deposit date: | 2014-09-16 | | Release date: | 2017-02-01 | | Last modified: | 2018-06-13 | | Method: | SOLUTION NMR | | Cite: | Structure-based drug design identifies polythiophenes as antiprion compounds.
Sci Transl Med, 7, 2015
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6RTB
 | | cryo-em structure of alpha-synuclein fibril polymorph 2B | | Descriptor: | Alpha-synuclein | | Authors: | Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. | | Deposit date: | 2019-05-22 | | Release date: | 2019-06-26 | | Last modified: | 2021-02-10 | | Method: | ELECTRON MICROSCOPY (3.46 Å) | | Cite: | Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.
Elife, 8, 2019
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6RT0
 | | cryo-em structure of alpha-synuclein fibril polymorph 2A | | Descriptor: | Alpha-synuclein | | Authors: | Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. | | Deposit date: | 2019-05-22 | | Release date: | 2019-06-26 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.
Elife, 8, 2019
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6TUB
 | | Beta-endorphin amyloid fibril | | Descriptor: | Beta-endorphin | | Authors: | Verasdonck, J, Seuring, C, Gath, J, Ghosh, D, Nespovitaya, N, Waelti, M.A, Maji, S, Cadalbert, R, Boeckmann, A, Guentert, P, Meier, B.H, Riek, R. | | Deposit date: | 2020-01-05 | | Release date: | 2020-10-28 | | Last modified: | 2020-12-16 | | Method: | SOLID-STATE NMR | | Cite: | The three-dimensional structure of human beta-endorphin amyloid fibrils.
Nat.Struct.Mol.Biol., 27, 2020
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8AAC
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8C0O
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2RNM
 | | Structure of The HET-s(218-289) prion in its amyloid form obtained by solid-state NMR | | Descriptor: | Small s protein | | Authors: | Wasmer, C, Lange, A, Van Melckebeke, H, Siemer, A, Riek, R, Meier, B.H. | | Deposit date: | 2008-01-24 | | Release date: | 2008-04-01 | | Last modified: | 2015-07-08 | | Method: | SOLUTION NMR | | Cite: | Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core
Science, 319, 2008
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6SSX
 | | cryo-em structure of alpha-synuclein fibril polymorph 2A | | Descriptor: | Alpha-synuclein | | Authors: | Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. | | Deposit date: | 2019-09-09 | | Release date: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.
Elife, 8, 2019
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6SST
 | | cryo-em structure of alpha-synuclein fibril polymorph 2B | | Descriptor: | Alpha-synuclein | | Authors: | Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. | | Deposit date: | 2019-09-09 | | Release date: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.
Elife, 8, 2019
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2JZZ
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2LBU
 | | HADDOCK calculated model of Congo red bound to the HET-s amyloid | | Descriptor: | Small s protein, sodium 3,3'-(1E,1'E)-biphenyl-4,4'-diylbis(diazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) | | Authors: | Schutz, A.K, Soragni, A, Hornemann, S, Aguzzi, A, Ernst, M, Bockmann, A, Meier, B.H. | | Deposit date: | 2011-04-07 | | Release date: | 2011-06-01 | | Last modified: | 2011-07-13 | | Method: | SOLID-STATE NMR | | Cite: | The Amyloid-Congo Red Interface at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 2011
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2L3Z
 | | Proton-Detected 4D DREAM Solid-State NMR Structure of Ubiquitin | | Descriptor: | Ubiquitin | | Authors: | Huber, M, Hiller, S, Schanda, P, Ernst, M, Bockmann, A, Verel, R, Meier, B.H. | | Deposit date: | 2010-09-27 | | Release date: | 2011-02-16 | | Last modified: | 2011-07-13 | | Method: | SOLID-STATE NMR | | Cite: | A Proton-Detected 4D Solid-State NMR Experiment for Protein Structure Determination.
Chemphyschem, 12, 2011
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2MVX
 | | Atomic-resolution 3D structure of amyloid-beta fibrils: the Osaka mutation | | Descriptor: | Amyloid beta A4 protein | | Authors: | Schuetz, A.K, Vagt, T, Huber, M, Ovchinnikova, O.Y, Cadalbert, R, Wall, J, Guentert, P, Bockmann, A, Glockshuber, R, Meier, B.H. | | Deposit date: | 2014-10-17 | | Release date: | 2014-11-26 | | Last modified: | 2015-01-21 | | Method: | SOLID-STATE NMR | | Cite: | Atomic-Resolution Three-Dimensional Structure of Amyloid beta Fibrils Bearing the Osaka Mutation.
Angew.Chem.Int.Ed.Engl., 54, 2015
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2NAO
 | | Atomic resolution structure of a disease-relevant Abeta(1-42) amyloid fibril | | Descriptor: | Beta-amyloid protein 42 | | Authors: | Waelti, M.A, Ravotti, F, Arai, H, Glabe, C, Wall, J, Bockmann, A, Guntert, P, Meier, B.H, Riek, R. | | Deposit date: | 2016-01-07 | | Release date: | 2016-07-27 | | Last modified: | 2016-09-07 | | Method: | SOLUTION NMR | | Cite: | Atomic-resolution structure of a disease-relevant A beta (1-42) amyloid fibril.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1S9Z
 | | SYNTHETIC 17 AMINO ACID LONG PEPTIDE THAT FORMS A NATIVE-LIKE COILED-COIL AT AMBIENT TEMPERATURE AND AGGREGATES INTO AMYLOID-LIKE FIBRILS AT HIGHER TEMPERATURES. | | Descriptor: | SODIUM ION, SYNTHETIC COILED-COIL PEPTIDE, ZINC ION | | Authors: | Kammerer, R.A, Kostrewa, D, Zurdo, J, Detken, A, Garcia-Echeverria, C, Green, J.D, Muller, S.A, Meier, B.H, Winkler, F.K, Dobson, C.M, Steinmetz, M.O. | | Deposit date: | 2004-02-06 | | Release date: | 2004-04-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Exploring amyloid formation by a de novo design
Proc.Natl.Acad.Sci.USA, 101, 2004
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2N1F
 | | Structure and assembly of the mouse ASC filament by combined NMR spectroscopy and cryo-electron microscopy | | Descriptor: | Apoptosis-associated speck-like protein | | Authors: | Sborgi, L, Ravotti, F, Dandey, V, Dick, M, Mazur, A, Reckel, S, Chami, M, Scherer, S, Bockmann, A, Egelman, E, Stahlberg, H, Broz, P, Meier, B, Hiller, S. | | Deposit date: | 2015-04-01 | | Release date: | 2015-10-14 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR | | Cite: | Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6GT7
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6GVU
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6GVQ
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8PSV
 | | 2.7 A cryo-EM structure of in vitro assembled type 1 pilus rod | | Descriptor: | Type-1 fimbrial protein, A chain | | Authors: | Hospenthal, M, Zyla, D, Glockshuber, R, Waksman, G. | | Deposit date: | 2023-07-13 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili.
Nat Commun, 15, 2024
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8PTU
 | | 2.5 A cryo-EM structure of the in vitro FimD-catalyzed assembly of type 1 pilus rod | | Descriptor: | Type-1 fimbrial protein, A chain | | Authors: | Zyla, D, Hospenthal, M, Glockshuber, R, Waksman, G. | | Deposit date: | 2023-07-14 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili.
Nat Commun, 15, 2024
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6C97
 | | Crystal structure of FcRn at pH3 | | Descriptor: | Beta-2-microglobulin, GLYCEROL, IgG receptor FcRn large subunit p51 | | Authors: | Fox III, D, Fairman, J.W. | | Deposit date: | 2018-01-25 | | Release date: | 2018-05-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
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6C98
 | | Crystal structure of FcRn bound to UCB-84 | | Descriptor: | 1-[7-(3-fluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethan-1-one, Beta-2-microglobulin, CYSTEINE, ... | | Authors: | Fox III, D, Lukacs, C.M. | | Deposit date: | 2018-01-25 | | Release date: | 2018-05-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
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