Author results

3G73
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STRUCTURE OF THE FOXM1 DNA BINDING
Descriptor:Forkhead box protein M1, DNA (5'-D(P*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(P*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), ...
Authors:Littler, D.R., Perrakis, A., Hibbert, R.G., Medema, R.H.
Deposit date:2009-02-09
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence
Nucleic Acids Res., 2010
2WVR
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HUMAN CDT1:GEMININ COMPLEX
Descriptor:GEMININ, DNA REPLICATION FACTOR CDT1
Authors:De Marco, V., Perrakis, A.
Deposit date:2009-10-19
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Quaternary Structure of the Human Cdt1-Geminin Complex Regulates DNA Replication Licensing.
Proc.Natl.Acad.Sci.USA, 106, 2009
5MRB
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CRYSTAL STRUCTURE OF HUMAN MPS1 (TTK) IN COMPLEX WITH CPD-5
Descriptor:Dual specificity protein kinase TTK, ~{N}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide, 1,2-ETHANEDIOL, ...
Authors:Hiruma, Y., Joosten, R.P., Perrakis, A.
Deposit date:2016-12-22
Release date:2017-07-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
J. Biol. Chem., 292, 2017
5NTT
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CRYSTAL STRUCTURE OF HUMAN MPS1 (TTK) C604Y MUTANT IN COMPLEX WITH NMS-P715
Descriptor:Dual specificity protein kinase TTK, N-(2,6-DIETHYLPHENYL)-1-METHYL-8-({4-[(1-METHYLPIPERIDIN-4-YL)CARBAMOYL]-2-(TRIFLUOROMETHOXY)PHENYL}AMINO)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE, 1,2-ETHANEDIOL
Authors:Hiruma, Y., Joosten, R.P., Perrakis, A.
Deposit date:2017-04-28
Release date:2017-07-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
J. Biol. Chem., 292, 2017
5O91
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CRYSTAL STRUCTURE OF HUMAN MPS1 (TTK) C604W MUTANT IN COMPLEX WITH CPD-5
Descriptor:Dual specificity protein kinase TTK, ~{N}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide, 1,2-ETHANEDIOL
Authors:Hiruma, Y., Joosten, R.P., Perrakis, A.
Deposit date:2017-06-15
Release date:2017-07-26
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
J. Biol. Chem., 292, 2017