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1QQT
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BU of 1qqt by Molmil
METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI
Descriptor: METHIONYL-TRNA SYNTHETASE, ZINC ION
Authors:Mechulam, Y, Schmitt, E, Maveyraud, L, Zelwer, C, Nureki, O, Yokoyama, S, Konno, M, Blanquet, S.
Deposit date:1999-06-08
Release date:2000-01-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features.
J.Mol.Biol., 294, 1999
3V11
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BU of 3v11 by Molmil
Structure of the ternary initiation complex AIF2:GDPNP:methionylated initiator TRNA
Descriptor: Initiator tRNA, MAGNESIUM ION, METHIONINE, ...
Authors:Mechulam, Y, Schmitt, E.
Deposit date:2011-12-09
Release date:2012-03-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:Structure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNA.
Nat.Struct.Mol.Biol., 19, 2012
2QN6
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BU of 2qn6 by Molmil
Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Translation initiation factor 2 alpha subunit, ...
Authors:Mechulam, Y, Yatime, L, Blanquet, S, Schmitt, E.
Deposit date:2007-07-18
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states.
Proc.Natl.Acad.Sci.Usa, 104, 2007
5OCD
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BU of 5ocd by Molmil
structure of a CDPS from Fluoribacter dumoffii
Descriptor: Cyclodipeptide synthase
Authors:Schmitt, E, Mechulam, Y, Bourgeois, G.
Deposit date:2017-06-30
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J. Struct. Biol., 203, 2018
8BRW
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BU of 8brw by Molmil
Escherichia coli methionyl-tRNA synthetase mutant L13C,I297C
Descriptor: Methionine--tRNA ligase, ZINC ION
Authors:Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T.
Deposit date:2022-11-24
Release date:2023-08-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
8BRX
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BU of 8brx by Molmil
Escherichia coli methionyl-tRNA synthetase mutant L13C,I297C complexed with beta-3-methionine
Descriptor: (3R)-3-amino-5-(methylsulfanyl)pentanoic acid, CITRIC ACID, Methionine--tRNA ligase, ...
Authors:Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T.
Deposit date:2022-11-24
Release date:2023-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
8BRU
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BU of 8bru by Molmil
Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C
Descriptor: CITRIC ACID, Methionine--tRNA ligase, ZINC ION
Authors:Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T.
Deposit date:2022-11-24
Release date:2023-08-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
8BRV
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BU of 8brv by Molmil
Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C complexed with beta3-methionine.
Descriptor: (3R)-3-amino-5-(methylsulfanyl)pentanoic acid, CITRIC ACID, Methionine--tRNA ligase, ...
Authors:Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T.
Deposit date:2022-11-24
Release date:2023-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
2FMT
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BU of 2fmt by Molmil
METHIONYL-TRNAFMET FORMYLTRANSFERASE COMPLEXED WITH FORMYL-METHIONYL-TRNAFMET
Descriptor: FORMYL-METHIONYL-TRNAFMET2, MAGNESIUM ION, METHIONYL-TRNA FMET FORMYLTRANSFERASE, ...
Authors:Schmitt, E, Mechulam, Y, Blanquet, S.
Deposit date:1998-07-29
Release date:1999-07-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet.
EMBO J., 17, 1998
6Q6R
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BU of 6q6r by Molmil
Recognition of different base tetrads by RHAU: X-ray crystal structure of G4 recognition motif bound to the 3-end tetrad of a DNA G-quadruplex
Descriptor: ATP-dependent DNA/RNA helicase DHX36, POTASSIUM ION, Parallel stranded DNA G-quadruplex
Authors:Heddi, B, Cheong, V.V, Schmitt, E, Mechulam, Y, Phan, A.T.
Deposit date:2018-12-11
Release date:2019-10-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex.
J.Struct.Biol., 209, 2020
6QJO
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BU of 6qjo by Molmil
DNA containing both right- and left-handed parallel-stranded G-quadruplexes
Descriptor: DNA (28-MER), POTASSIUM ION
Authors:Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Schmitt, E, Mechulam, Y, Phan, A.T.
Deposit date:2019-01-24
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
6GZ6
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BU of 6gz6 by Molmil
Structure of a left-handed G-quadruplex
Descriptor: DNA (27-MER), POTASSIUM ION
Authors:Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T.
Deposit date:2018-07-03
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew.Chem.Int.Ed.Engl., 58, 2019
3M4X
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BU of 3m4x by Molmil
Structure of a ribosomal methyltransferase
Descriptor: NOL1/NOP2/sun family protein
Authors:Galimand, M, Schmitt, E, Panvert, M, Mechulam, Y, Courvalin, P.
Deposit date:2010-03-12
Release date:2010-04-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of an RNA methyltransferase
To be Published
6Y4B
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BU of 6y4b by Molmil
Structure of cyclodipeptide synthase from Candidatus Glomeribacter gigasporarum bound to Phe-tRNAPhe
Descriptor: Cyclodipeptide synthase, PHENYLALANINE, RNA (77-MER)
Authors:Bourgeois, G, Mechulam, Y, Schmitt, E.
Deposit date:2020-02-20
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (5 Å)
Cite:Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates.
Rna, 26, 2020
6Y3G
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BU of 6y3g by Molmil
Crystal structure of phenylalanine tRNA from Escherichia coli
Descriptor: CALCIUM ION, GLYCEROL, GUANIDINE, ...
Authors:Bourgeois, G, Mechulam, Y, Schmitt, E.
Deposit date:2020-02-18
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates.
Rna, 26, 2020
1XTY
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BU of 1xty by Molmil
Crystal structure of Sulfolobus solfataricus peptidyl-tRNA hydrolase
Descriptor: Peptidyl-tRNA hydrolase, SULFATE ION
Authors:Fromant, M, Schmitt, E, Mechulam, Y, Lazennec, C, Plateau, P, Blanquet, S.
Deposit date:2004-10-25
Release date:2005-03-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure at 1.8 A resolution and identification of active site residues of Sulfolobus solfataricus peptidyl-tRNA hydrolase.
Biochemistry, 44, 2005
6EZ3
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BU of 6ez3 by Molmil
Structure of CDPS from Staphylococcus haemolyticus
Descriptor: Cyclo(L-leucyl-L-leucyl) synthase, SULFATE ION
Authors:Schmitt, E, Mechulam, Y, Bourgeois, G.
Deposit date:2017-11-14
Release date:2018-11-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J. Struct. Biol., 203, 2018
1FMT
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BU of 1fmt by Molmil
METHIONYL-TRNAFMET FORMYLTRANSFERASE FROM ESCHERICHIA COLI
Descriptor: METHIONYL-TRNA FMET FORMYLTRANSFERASE
Authors:Schmitt, E, Mechulam, Y.
Deposit date:1997-10-13
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of crystalline Escherichia coli methionyl-tRNA(f)Met formyltransferase: comparison with glycinamide ribonucleotide formyltransferase.
EMBO J., 15, 1996
6FQ2
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BU of 6fq2 by Molmil
Structure of minimal sequence for left -handed G-quadruplex formation
Descriptor: DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION
Authors:Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B.
Deposit date:2018-02-13
Release date:2018-12-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew. Chem. Int. Ed. Engl., 58, 2019
5L4O
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BU of 5l4o by Molmil
Structure of an E.coli initiator tRNAfMet A1-U72 variant
Descriptor: SODIUM ION, tRNA (76-MER)
Authors:Monestier, A, Schmitt, E, Mechulam, Y.
Deposit date:2016-05-26
Release date:2017-03-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:The structure of an E. coli tRNAf(Met) A1-U72 variant shows an unusual conformation of the A1-U72 base pair.
RNA, 23, 2017
5MLQ
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BU of 5mlq by Molmil
Structure of CDPS from Nocardia brasiliensis
Descriptor: CDPS, CITRIC ACID
Authors:Bourgeois, G, Seguin, J, Moutiez, M, Babin, M, Belin, P, Mechulam, Y, Gondry, M, Schmitt, E.
Deposit date:2016-12-07
Release date:2018-05-02
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J.Struct.Biol., 203, 2018
5MLP
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BU of 5mlp by Molmil
Structure of CDPS from Rickettsiella grylli
Descriptor: Uncharacterized protein
Authors:Bourgeois, G, Seguin, J, Moutiez, M, Babin, M, Belin, P, Mechulam, Y, Gondry, M, Schmitt, E.
Deposit date:2016-12-07
Release date:2018-05-02
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J.Struct.Biol., 203, 2018
6JCE
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BU of 6jce by Molmil
NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes
Descriptor: 29-mer DNA
Authors:Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Mechulam, Y, Schmitt, E, Phan, A.T.
Deposit date:2019-01-28
Release date:2019-07-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
5JB3
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BU of 5jb3 by Molmil
Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-REMOTE conformation
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Coureux, P.-D, Schmitt, E, Mechulam, Y.
Deposit date:2016-04-13
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.34 Å)
Cite:Cryo-EM study of start codon selection during archaeal translation initiation.
Nat Commun, 7, 2016
5JBH
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BU of 5jbh by Molmil
Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-IN conformation
Descriptor: 16S ribosomal RNA, 30S ribosomal protein SX, 30S ribosomal protein eL41, ...
Authors:Coureux, P.-D, Schmitt, E, Mechulam, Y.
Deposit date:2016-04-13
Release date:2016-12-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.34 Å)
Cite:Cryo-EM study of start codon selection during archaeal translation initiation.
Nat Commun, 7, 2016

 

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