1QQT
| METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI | Descriptor: | METHIONYL-TRNA SYNTHETASE, ZINC ION | Authors: | Mechulam, Y, Schmitt, E, Maveyraud, L, Zelwer, C, Nureki, O, Yokoyama, S, Konno, M, Blanquet, S. | Deposit date: | 1999-06-08 | Release date: | 2000-01-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features. J.Mol.Biol., 294, 1999
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3V11
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2QN6
| Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Translation initiation factor 2 alpha subunit, ... | Authors: | Mechulam, Y, Yatime, L, Blanquet, S, Schmitt, E. | Deposit date: | 2007-07-18 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states. Proc.Natl.Acad.Sci.Usa, 104, 2007
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8BRX
| Escherichia coli methionyl-tRNA synthetase mutant L13C,I297C complexed with beta-3-methionine | Descriptor: | (3R)-3-amino-5-(methylsulfanyl)pentanoic acid, CITRIC ACID, Methionine--tRNA ligase, ... | Authors: | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | Deposit date: | 2022-11-24 | Release date: | 2023-08-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments. Protein Sci., 32, 2023
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8BRV
| Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C complexed with beta3-methionine. | Descriptor: | (3R)-3-amino-5-(methylsulfanyl)pentanoic acid, CITRIC ACID, Methionine--tRNA ligase, ... | Authors: | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | Deposit date: | 2022-11-24 | Release date: | 2023-08-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments. Protein Sci., 32, 2023
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8BRW
| Escherichia coli methionyl-tRNA synthetase mutant L13C,I297C | Descriptor: | Methionine--tRNA ligase, ZINC ION | Authors: | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | Deposit date: | 2022-11-24 | Release date: | 2023-08-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments. Protein Sci., 32, 2023
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8BRU
| Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C | Descriptor: | CITRIC ACID, Methionine--tRNA ligase, ZINC ION | Authors: | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | Deposit date: | 2022-11-24 | Release date: | 2023-08-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments. Protein Sci., 32, 2023
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6Y4B
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6Y3G
| Crystal structure of phenylalanine tRNA from Escherichia coli | Descriptor: | CALCIUM ION, GLYCEROL, GUANIDINE, ... | Authors: | Bourgeois, G, Mechulam, Y, Schmitt, E. | Deposit date: | 2020-02-18 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates. Rna, 26, 2020
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2MS9
| Solution structure of a G-quadruplex | Descriptor: | DNA (28-MER) | Authors: | Chung, W.J, Heddi, B, Schmitt, E, Lim, K.W, Mechulam, Y, Phan, A.T. | Deposit date: | 2014-07-25 | Release date: | 2015-02-18 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structure of a left-handed DNA G-quadruplex Proc.Natl.Acad.Sci.USA, 2015
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1FMT
| METHIONYL-TRNAFMET FORMYLTRANSFERASE FROM ESCHERICHIA COLI | Descriptor: | METHIONYL-TRNA FMET FORMYLTRANSFERASE | Authors: | Schmitt, E, Mechulam, Y. | Deposit date: | 1997-10-13 | Release date: | 1998-01-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of crystalline Escherichia coli methionyl-tRNA(f)Met formyltransferase: comparison with glycinamide ribonucleotide formyltransferase. EMBO J., 15, 1996
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4RCY
| Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GTP | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E. | Deposit date: | 2014-09-18 | Release date: | 2015-05-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2. Nucleic Acids Res., 43, 2015
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4RD0
| Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDP | Descriptor: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E. | Deposit date: | 2014-09-18 | Release date: | 2015-05-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.713 Å) | Cite: | Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2. Nucleic Acids Res., 43, 2015
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4U5M
| Structure of a left-handed DNA G-quadruplex | Descriptor: | DNA (28-MER), MAGNESIUM ION, POTASSIUM ION | Authors: | Schmitt, E, Mechulam, Y, Phan, A.T, Brahim, H, Chung, W.J, Lim, K.W. | Deposit date: | 2014-07-25 | Release date: | 2015-02-25 | Last modified: | 2015-03-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a left-handed DNA G-quadruplex. Proc.Natl.Acad.Sci.USA, 112, 2015
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6Q6R
| Recognition of different base tetrads by RHAU: X-ray crystal structure of G4 recognition motif bound to the 3-end tetrad of a DNA G-quadruplex | Descriptor: | ATP-dependent DNA/RNA helicase DHX36, POTASSIUM ION, Parallel stranded DNA G-quadruplex | Authors: | Heddi, B, Cheong, V.V, Schmitt, E, Mechulam, Y, Phan, A.T. | Deposit date: | 2018-12-11 | Release date: | 2019-10-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex. J.Struct.Biol., 209, 2020
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6QJO
| DNA containing both right- and left-handed parallel-stranded G-quadruplexes | Descriptor: | DNA (28-MER), POTASSIUM ION | Authors: | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Schmitt, E, Mechulam, Y, Phan, A.T. | Deposit date: | 2019-01-24 | Release date: | 2019-07-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. Nucleic Acids Res., 47, 2019
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6EZ3
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6FQ2
| Structure of minimal sequence for left -handed G-quadruplex formation | Descriptor: | DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION | Authors: | Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B. | Deposit date: | 2018-02-13 | Release date: | 2018-12-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | A Minimal Sequence for Left-Handed G-Quadruplex Formation. Angew. Chem. Int. Ed. Engl., 58, 2019
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6GZ6
| Structure of a left-handed G-quadruplex | Descriptor: | DNA (27-MER), POTASSIUM ION | Authors: | Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T. | Deposit date: | 2018-07-03 | Release date: | 2019-04-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.006 Å) | Cite: | A Minimal Sequence for Left-Handed G-Quadruplex Formation. Angew.Chem.Int.Ed.Engl., 58, 2019
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5L4O
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5MLQ
| Structure of CDPS from Nocardia brasiliensis | Descriptor: | CDPS, CITRIC ACID | Authors: | Bourgeois, G, Seguin, J, Moutiez, M, Babin, M, Belin, P, Mechulam, Y, Gondry, M, Schmitt, E. | Deposit date: | 2016-12-07 | Release date: | 2018-05-02 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | Structural basis for partition of the cyclodipeptide synthases into two subfamilies. J.Struct.Biol., 203, 2018
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5MLP
| Structure of CDPS from Rickettsiella grylli | Descriptor: | Uncharacterized protein | Authors: | Bourgeois, G, Seguin, J, Moutiez, M, Babin, M, Belin, P, Mechulam, Y, Gondry, M, Schmitt, E. | Deposit date: | 2016-12-07 | Release date: | 2018-05-02 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural basis for partition of the cyclodipeptide synthases into two subfamilies. J.Struct.Biol., 203, 2018
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5JB3
| Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-REMOTE conformation | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Coureux, P.-D, Schmitt, E, Mechulam, Y. | Deposit date: | 2016-04-13 | Release date: | 2016-11-30 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (5.34 Å) | Cite: | Cryo-EM study of start codon selection during archaeal translation initiation. Nat Commun, 7, 2016
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5JBH
| Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-IN conformation | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein SX, 30S ribosomal protein eL41, ... | Authors: | Coureux, P.-D, Schmitt, E, Mechulam, Y. | Deposit date: | 2016-04-13 | Release date: | 2016-12-07 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (5.34 Å) | Cite: | Cryo-EM study of start codon selection during archaeal translation initiation. Nat Commun, 7, 2016
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5OCD
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