Author results

2Y2G
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (A01)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, [(2,6-DIMETHOXYPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON, SULFATE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2H
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA2)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, [(2-CHLOROPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON, SULFATE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2I
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA3)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, TRIHYDROXY-[[(2-NITROPHENYL)CARBONYLAMINO]METHYL]BORON, SULFATE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2J
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA4)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, [(2-FLUOROPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON, SULFATE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol, 6, 2011
2Y2K
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA5)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, [(2,6-DIFLUOROPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON, SULFATE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol, 6, 2011
2Y2L
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (E06)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, [(1R)-1-[(2,6-difluorophenyl)carbonylamino]ethyl]-trihydroxy-boron, SULFATE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2M
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (E08)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, TRIHYDROXY-[(1S)-1-[(2-PROPAN-2-YLPHENYL)CARBONYLAMINO]ETHYL]BORON, CHLORIDE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2N
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (E07)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, TRIHYDROXY-[(1S)-1-[[2-(PHENYLMETHYL)PHENYL]CARBONYLAMINO]ETHYL]BORON, CHLORIDE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2O
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (EO9)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, [(1S)-1-[(2,6-difluorophenyl)carbonylamino]ethyl]-trihydroxy-boron, SULFATE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2P
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (Z10)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, [(1S)-1-[(2-fluoro-6-phenyl-phenyl)carbonylamino]ethyl]-trihydroxy-boron, CHLORIDE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
2Y2Q
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PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (Z06)
Descriptor:PENICILLIN-BINDING PROTEIN 1B, (3-acetamido-5-carboxy-phenyl)-trihydroxy-boron, SULFATE ION, ...
Authors:Contreras-Martel, C., Amoroso, A., Woon, E.C., Zervosen, A., Inglis, S., Martins, A., Verlaine, O., Rydzik, A., Job, V., Luxen, A., Joris, B., Schofield, C.J., Dessen, A.
Deposit date:2010-12-15
Release date:2011-08-03
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol., 6, 2011
1I9S
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CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor:MRNA CAPPING ENZYME, SULFATE ION, CACODYLATE ION, ...
Authors:Changela, A., Ho, C.K., Martins, A., Shuman, S., Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
1I9T
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CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor:MRNA CAPPING ENZYME, SULFATE ION, CACODYLATE ION, ...
Authors:Changela, A., Ho, C.K., Martins, A., Shuman, S., Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
1YN9
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CRYSTAL STRUCTURE OF BACULOVIRUS RNA 5'-PHOSPHATASE COMPLEXED WITH PHOSPHATE
Descriptor:polynucleotide 5'-phosphatase, PHOSPHATE ION
Authors:Changela, A., Martins, A., Shuman, S., Mondragon, A.
Deposit date:2005-01-24
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of baculovirus RNA triphosphatase complexed with phosphate
J.Biol.Chem., 280, 2005
2WAD
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PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)
Descriptor:PENICILLIN-BINDING PROTEIN 2B, ZINC ION
Authors:Contreras-Martel, C., Dahout-Gonzalez, C., Dos-Santos-Martins, A., Kotnik, M., Dessen, A.
Deposit date:2009-02-05
Release date:2009-02-24
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
2WAE
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PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)
Descriptor:PENICILLIN-BINDING PROTEIN 2B, ZINC ION
Authors:Contreras-Martel, C., Dahout-Gonzalez, C., Dos-Santos-Martins, A., Kotnik, M., Dessen, A.
Deposit date:2009-02-05
Release date:2009-02-24
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
2WAF
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PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN R6)
Descriptor:PENICILLIN-BINDING PROTEIN 2B, CHLORIDE ION
Authors:Contreras-Martel, C., Dahout-Gonzalez, C., Dos-Santos-Martins, A., Kotnik, M., Dessen, A.
Deposit date:2009-02-05
Release date:2009-02-24
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
4U39
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CRYSTAL STRUCTURE OF FTSZ:MCIZ COMPLEX FROM BACILLUS SUBTILIS
Descriptor:Cell division protein FtsZ, Cell division factor, PHOSPHATE ION
Authors:Bisson-Filho, A.W., Discola, K.F., Castellen, P., Blasios, V., Martins, A., Sforca, M.L., Garcia, W., Zeri, A.C., Erickson, H.P., Dessen, A., Gueiros-Filho, F.J.
Deposit date:2014-07-19
Release date:2015-03-18
Method:X-RAY DIFFRACTION (3.194 Å)
Cite:Crystal Structure of FtsZ:MciZ Complex from Bacillus subtilis
To be Published
5LP4
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PENICILLIN-BINDING PROTEIN (PBP2) FROM HELICOBACTER PYLORI
Descriptor:Penicillin-binding protein 2 (Pbp2), SULFATE ION
Authors:Contreras-Martel, C., Martins, A., Ecobichon, C., Maragno, D.M., Mattei, P.J., El Ghachi, M., Boneca, I.G., Dessen, A.
Deposit date:2016-08-11
Release date:2017-08-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Molecular architecture of the PBP2-MreC core bacterial cell wall synthesis complex.
Nat Commun, 8, 2017
5LP5
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COMPLEX BETWEEN PENICILLIN-BINDING PROTEIN (PBP2) AND MREC FROM HELICOBACTER PYLORI
Descriptor:Penicillin-binding protein 2 (Pbp2), Rod shape-determining protein (MreC)
Authors:Contreras-Martel, C., Martins, A., Ecobichon, C., Maragno, D.M., Mattei, P.J., El Ghachi, M., Hicham, S., Hardouin, P., Boneca, I.G., Dessen, A.
Deposit date:2016-08-11
Release date:2017-08-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Molecular architecture of the PBP2-MreC core bacterial cell wall synthesis complex.
Nat Commun, 8, 2017
6I2V
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PILOTIN FROM VIBRIO VULNIFICUS TYPE 2 SECRETION SYSTEM, EPSS.
Descriptor:Uncharacterized protein, PENTAETHYLENE GLYCOL, 1,2-ETHANEDIOL, ...
Authors:Howard, S.P., Estrozi, L., Bertrand, Q., Contreras-Martel, C., Strozen, T., Job, V., Martins, A., Fenel, D., Schoehn, G., Dessen, A.
Deposit date:2018-11-02
Release date:2019-04-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and assembly of pilotin-dependent and -independent secretins of the Type II Secretion System
To Be Published
1HZF
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C4ADG FRAGMENT OF HUMAN COMPLEMENT FACTOR C4A
Descriptor:COMPLEMENT FACTOR C4A
Authors:van den Elsen, J.M.H., Martin, A., Wong, V., Clemenza, L., Rose, D.R., Isenman, D.E.
Deposit date:2001-01-24
Release date:2002-10-09
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystal structure of the C4d fragment of human complement component C4.
J.Mol.Biol., 322, 2002
1VS0
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CRYSTAL STRUCTURE OF THE LIGASE DOMAIN FROM M. TUBERCULOSIS LIGD AT 2.4A
Descriptor:Putative DNA ligase-like protein Rv0938/MT0965, ZINC ION, CHLORIDE ION, ...
Authors:Akey, D., Martins, A., Aniukwu, J., Glickman, M.S., Shuman, S., Berger, J.M., TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-01-27
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure and Nonhomologous End-joining Function of the Ligase Component of Mycobacterium DNA Ligase D.
J.Biol.Chem., 281, 2006
2LZP
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STRUCTURE OF NS2(2-32) GBVB PROTEIN
Descriptor:NS2 peptide
Authors:Montserret, R., Penin, F., Martin, A.
Deposit date:2012-10-08
Release date:2014-04-09
Last modified:2014-06-18
Method:SOLUTION NMR
Cite:NS2 Proteins of GB Virus B and Hepatitis C Virus Share Common Protease Activities and Membrane Topologies.
J.Virol., 88, 2014
2LZQ
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STRUCTURE OF NS2(32-57) GBVB PROTEIN
Descriptor:NS2 peptide
Authors:Montserret, R., Penin, F., Martin, A.
Deposit date:2012-10-08
Release date:2014-04-09
Last modified:2014-06-18
Method:SOLUTION NMR
Cite:NS2 Proteins of GB Virus B and Hepatitis C Virus Share Common Protease Activities and Membrane Topologies.
J.Virol., 88, 2014
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