Author results

1PYI
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CRYSTAL STRUCTURE OF A PPR1-DNA COMPLEX: DNA RECOGNITION BY PROTEINS CONTAINING A ZN2CYS6 BINUCLEAR CLUSTER
Descriptor:DNA (5'-D(*TP*CP*GP*GP*CP*AP*AP*TP*TP*GP*CP*CP*GP*A)-3'), PROTEIN (PYRIMIDINE PATHWAY REGULATOR 1), ZINC ION
Authors:Marmorstein, R., Harrison, S.C.
Deposit date:1995-01-04
Release date:1995-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a PPR1-DNA complex: DNA recognition by proteins containing a Zn2Cys6 binuclear cluster.
Genes Dev., 8, 1994
1D66
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DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX
Descriptor:DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*AP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*TP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), PROTEIN (GAL4), ...
Authors:Marmorstein, R., Carey, M., Ptashne, M., Harrison, S.C.
Deposit date:1992-03-06
Release date:1992-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:DNA recognition by GAL4: structure of a protein-DNA complex.
Nature, 356, 1992
2I32
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STRUCTURE OF A HUMAN ASF1A-HIRA COMPLEX AND INSIGHTS INTO SPECIFICITY OF HISTONE CHAPERONE COMPLEX ASSEMBLY
Descriptor:Anti-Silencing Factor 1 paralog a, Histone Regulatory homolog A
Authors:Marmorstein, R., Tang, Y.
Deposit date:2006-08-17
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly.
Nat.Struct.Mol.Biol., 13, 2006
1MX2
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STRUCTURE OF F71N MUTANT OF P18INK4C
Descriptor:Cyclin-dependent kinase 6 inhibitor
Authors:Marmorstein, R., Venkataramani, R.N., MacLachlan, T.K., Chai, X., El-Deiery, W.S.
Deposit date:2002-10-01
Release date:2002-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity
J.Biol.Chem., 277, 2002
1MX4
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STRUCTURE OF P18INK4C (F82Q)
Descriptor:Cyclin-dependent kinase 6 inhibitor
Authors:Marmorstein, R., Venkataramani, R.N., MacLachlan, T.K., Chai, X., El-Deiry, W.S.
Deposit date:2002-10-01
Release date:2002-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity
J.Biol.Chem., 277, 2002
1MX6
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STRUCTURE OF P18INK4C (F92N)
Descriptor:Cyclin-dependent kinase 6 inhibitor
Authors:Marmorstein, R., Venkataramani, R.N., MacLachlan, T.K., Chai, X., El-Deiry, W.S.
Deposit date:2002-10-01
Release date:2002-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity
J.Biol.Chem., 277, 2002
2OD9
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STRUCTURAL BASIS FOR NICOTINAMIDE INHIBITION AND BASE EXCHANGE IN SIR2 ENZYMES
Descriptor:NAD-dependent deacetylase HST2, H4 peptide, ZINC ION, ...
Authors:Marmorstein, R., Sanders, B.D.
Deposit date:2006-12-21
Release date:2007-02-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Mol.Cell, 25, 2007
2QQF
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HST2 BOUND TO ADP-HPD AND ACETYLATED HISTONE H4
Descriptor:NAD-dependent deacetylase HST2, Histone H4, ZINC ION, ...
Authors:Marmorstein, R., Sanders, B.D., Zhao, K., Slama, J.
Deposit date:2007-07-26
Release date:2007-10-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Mol.Cell, 25, 2007
2QQG
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HST2 BOUND TO ADP-HPD, ACETYLLATED HISTONE H4 AND NICOTINAMIDE
Descriptor:NAD-dependent deacetylase HST2, Histone H4, ZINC ION, ...
Authors:Marmorstein, R., Sanders, B., Zhao, K., Slama, J.
Deposit date:2007-07-26
Release date:2007-10-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Mol.Cell, 25, 2007
4ZBJ
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UBN1 PEPTIDE BOUND TO H3.3/H4/ASF1
Descriptor:Histone chaperone ASF1, Histone H3, Histone H4, ...
Authors:Marmorstein, R., Ricketts, M.D., Tang, Y.
Deposit date:2015-04-14
Release date:2015-07-15
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex.
Nat Commun, 6, 2015
5T53
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MOLECULAR BASIS FOR COHESIN ACETYLATION BY ESTABLISHMENT OF SISTER CHROMATID COHESION N-ACETYLTRANSFERASE ESCO1
Descriptor:N-acetyltransferase ESCO1, ACETYL COENZYME *A, ZINC ION
Authors:Marmorstein, R., Rivera-Colon, Y., Liszczak, G.P., Olia, A.S., Maguire, A.
Deposit date:2016-08-30
Release date:2016-11-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Molecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-Acetyltransferase ESCO1.
J. Biol. Chem., 291, 2016
1SZD
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STRUCTURAL BASIS FOR NICOTINAMIDE CLEAVAGE AND ADP-RIBOSE TRANSFER BY NAD+-DEPENDENT SIR2 HISTONE/PROTEIN DEACETYLASES
Descriptor:NAD-dependent deacetylase HST2, Histone H4 peptide, CHLORIDE ION, ...
Authors:Zhao, K., Harshaw, R., Chai, X., Marmorstein, R.
Deposit date:2004-04-05
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1SZC
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STRUCTURAL BASIS FOR NICOTINAMIDE CLEAVAGE AND ADP-RIBOSE TRANSFER BY NAD+-DEPENDENT SIR2 HISTONE/PROTEIN DEACETYLASES
Descriptor:NAD-dependent deacetylase HST2, Histone H4 peptide, ZINC ION, ...
Authors:Zhao, K., Harshaw, R., Chai, X., Marmorstein, R.
Deposit date:2004-04-05
Release date:2004-06-15
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1QP9
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STRUCTURE OF HAP1-PC7 COMPLEXED TO THE UAS OF CYC7
Descriptor:DNA (5'-D(*AP*CP*GP*CP*TP*AP*TP*TP*AP*TP*CP*GP*CP*TP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*AP*CP*TP*AP*AP*TP*AP*GP*CP*GP*AP*TP*AP*AP*TP*AP*GP*CP*GP*T)-3'), CYP1(HAP1-PC7) ACTIVATORY PROTEIN, ...
Authors:Lukens, A., King, D., Marmorstein, R.
Deposit date:1999-06-01
Release date:2000-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation.
Nucleic Acids Res., 28, 2000
3Q33
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STRUCTURE OF THE RTT109-ACCOA/VPS75 COMPLEX AND IMPLICATIONS FOR CHAPERONE-MEDIATED HISTONE ACETYLATION
Descriptor:Histone acetyltransferase RTT109, Vacuolar protein sorting-associated protein 75, HISTONE H3, ...
Authors:Tang, Y., Yuan, H., Meeth, K., Marmorstein, R.
Deposit date:2010-12-21
Release date:2011-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation.
Structure, 19, 2011
3Q35
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STRUCTURE OF THE RTT109-ACCOA/VPS75 COMPLEX AND IMPLICATIONS FOR CHAPERONE-MEDIATED HISTONE ACETYLATION
Descriptor:Histone acetyltransferase, Vacuolar protein sorting-associated protein 75, ACETYL COENZYME *A, ...
Authors:Tang, Y., Yuan, H., Meeth, K., Marmorstein, R.
Deposit date:2010-12-21
Release date:2011-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation.
Structure, 19, 2011
1Q17
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STRUCTURE OF THE YEAST HST2 PROTEIN DEACETYLASE IN TERNARY COMPLEX WITH 2'-O-ACETYL ADP RIBOSE AND HISTONE PEPTIDE
Descriptor:HST2 protein, ZINC ION, CHLORIDE ION, ...
Authors:Zhao, K., Chai, X., Marmorstein, R.
Deposit date:2003-07-18
Release date:2003-11-18
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2'-O-Acetyl ADP Ribose and Histone Peptide.
Structure, 11, 2003
1Q1A
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STRUCTURE OF THE YEAST HST2 PROTEIN DEACETYLASE IN TERNARY COMPLEX WITH 2'-O-ACETYL ADP RIBOSE AND HISTONE PEPTIDE
Descriptor:HST2 protein, Histone H4, ZINC ION, ...
Authors:Zhao, K., Chai, X., Marmorstein, R.
Deposit date:2003-07-18
Release date:2003-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-Acetyl ADP ribose and histone peptide.
Structure, 11, 2003
2QIY
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YEAST DEUBIQUITINASE UBP3 AND BRE5 COFACTOR COMPLEX
Descriptor:UBP3-associated protein BRE5, Ubiquitin carboxyl-terminal hydrolase 3
Authors:Li, K., Liu, X., Marmorstein, R.
Deposit date:2007-07-05
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Molecular basis for bre5 cofactor recognition by the ubp3 deubiquitylating enzyme.
J.Mol.Biol., 372, 2007
2YAK
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STRUCTURE OF DEATH-ASSOCIATED PROTEIN KINASE 1 (DAPK1) IN COMPLEX WITH A RUTHENIUM OCTASPORINE LIGAND (OSV)
Descriptor:DEATH-ASSOCIATED PROTEIN KINASE 1, RUTHENIUM OCTASPORINE 4
Authors:Feng, L., Geisselbrecht, Y., Blanck, S., Wilbuer, A., Atilla-Gokcumen, G.E., Filippakopoulos, P., Kraeling, K., Celik, M.A., Harms, K., Maksimoska, J., Marmorstein, R., Frenking, G., Knapp, S., Essen, L.-O., Meggers, E.
Deposit date:2011-02-23
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors.
J.Am.Chem.Soc., 133, 2011
1TRO
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CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION
Descriptor:DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN
Authors:Otwinowski, Z., Schevitz, R.W., Zhang, R.-G., Lawson, C.L., Joachimiak, A.J., Marmorstein, R., Luisi, B.F., Sigler, P.B.
Deposit date:1992-08-30
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of trp repressor/operator complex at atomic resolution.
Nature, 335, 1988
2FQ3
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STRUCTURE AND FUNCTION OF THE SWIRM DOMAIN, A CONSERVED PROTEIN MODULE FOUND IN CHROMATIN REGULATORY COMPLEXES
Descriptor:Transcription regulatory protein SWI3
Authors:Da, G., Lenkart, J., Zhao, K., Shiekhattar, R., Cairns, B.R., Marmorstein, R.
Deposit date:2006-01-17
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes
Proc.Natl.Acad.Sci.Usa, 103, 2006
3CO6
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CRYSTAL STRUCTURE OF FOXO1 DBD BOUND TO DBE1 DNA
Descriptor:DNA (5'-D(*DTP*DGP*DGP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DAP*DCP*DCP*DTP*DTP*DG)-3'), DNA (5'-D(*DCP*DAP*DAP*DGP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), Forkhead box protein O1, ...
Authors:Brent, M.M., Anand, R., Marmorstein, R.
Deposit date:2008-03-27
Release date:2008-09-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure, 16, 2008
3CO7
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CRYSTAL STRUCTURE OF FOXO1 DBD BOUND TO DBE2 DNA
Descriptor:DNA (5'-D(*DTP*DCP*DTP*DTP*DGP*DTP*DTP*DTP*DAP*DCP*DAP*DTP*DTP*DTP*DTP*DG)-3'), DNA (5'-D(*DCP*DAP*DAP*DAP*DAP*DTP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DGP*DA)-3'), Forkhead box protein O1
Authors:Brent, M.M., Anand, R., Marmorstein, R.
Deposit date:2008-03-27
Release date:2008-09-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure, 16, 2008
3COA
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CRYSTAL STRUCTURE OF FOXO1 DBD BOUND TO IRE DNA
Descriptor:DNA (5'-D(*DTP*DGP*DGP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DG)-3'), DNA (5'-D(*DCP*DAP*DAP*DGP*DCP*DAP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), Forkhead box protein O1, ...
Authors:Brent, M.M., Anand, R., Marmorstein, R.
Deposit date:2008-03-27
Release date:2008-09-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure, 16, 2008