Author results

1EJ1
  • Download 1ej1
  • View 1ej1
Molmil generated image of 1ej1
COCRYSTAL STRUCTURE OF THE MESSENGER RNA 5' CAP-BINDING PROTEIN (EIF4E) BOUND TO 7-METHYL-GDP
Descriptor:EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Marcotrigiano, J., Gingras, A.-C., Sonenberg, N., Burley, S.K.
Deposit date:2000-02-29
Release date:2000-03-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP.
Cell(Cambridge,Mass.), 89, 1997
1EJ4
  • Download 1ej4
  • View 1ej4
Molmil generated image of 1ej4
COCRYSTAL STRUCTURE OF EIF4E/4E-BP1 PEPTIDE
Descriptor:EUKARYOTIC INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E BINDING PROTEIN 1, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Marcotrigiano, J., Gingras, A.-C., Sonenberg, N., Burley, S.K.
Deposit date:2000-02-28
Release date:2000-03-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G.
Mol.Cell, 3, 1999
1EJH
  • Download 1ejh
  • View 1ejh
Molmil generated image of 1ejh
EIF4E/EIF4G PEPTIDE/7-METHYL-GDP
Descriptor:EUKARYOTIC INITIATION FACTOR 4E, EUKARYOTIC INITIATION FACTOR 4GII, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Marcotrigiano, J., Gingras, A.-C., Sonenberg, N., Burley, S.K.
Deposit date:2000-03-02
Release date:2000-03-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G.
Mol.Cell, 3, 1999
1HU3
  • Download 1hu3
  • View 1hu3
Molmil generated image of 1hu3
MIDDLE DOMAIN OF HUMAN EIF4GII
Descriptor:EIF4GII
Authors:Marcotrigiano, J., Lomakin, I., Pestova, T.V., Hellen, C.U.T., Sonenberg, N., Burley, S.K.
Deposit date:2001-01-03
Release date:2001-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery.
Mol.Cell, 7, 2001
1L8B
  • Download 1l8b
  • View 1l8b
Molmil generated image of 1l8b
COCRYSTAL STRUCTURE OF THE MESSENGER RNA 5' CAP-BINDING PROTEIN (EIF4E) BOUND TO 7-METHYLGPPPG
Descriptor:EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE
Authors:Niedzwiecka, A., Marcotrigiano, J., Stepinski, J., Jankowska-Anyszka, M., Wyslouch-Cieszynska, A., Dadlez, M., Gingras, A.-C., Mak, P., Darzynkiewicz, E., Sonenberg, N.
Deposit date:2002-03-19
Release date:2002-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins.
J.Mol.Biol., 319, 2002
4WEB
  • Download 4web
  • View 4web
Molmil generated image of 4web
STRUCTURE OF THE CORE ECTODOMAIN OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN 2
Descriptor:hepatitis C virus envelope glycoprotein 2, Mouse Fab Heavy Chain, Mouse Fab Light Chain, ...
Authors:Khan, A.G., Whidby, J., Miller, M.T., Scarborough, H., Zatorski, A.V., Cygan, A., Price, A.A., Yost, S.A., Bohannon, C.D., Jacob, J., Grakoui, A., Marcotrigiano, J.
Deposit date:2014-09-09
Release date:2014-12-17
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2.
Nature, 509, 2014
1ZH1
  • Download 1zh1
  • View 1zh1
Molmil generated image of 1zh1
STRUCTURE OF THE ZINC-BINDING DOMAIN OF HCV NS5A
Descriptor:non-structural polyprotein, ZINC ION
Authors:Tellinghuisen, T.L., Marcotrigiano, J., Rice, C.M.
Deposit date:2005-04-22
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase.
Nature, 435, 2005
2HD0
  • Download 2hd0
  • View 2hd0
Molmil generated image of 2hd0
STRUCTURE OF THE CATALYTIC DOMAIN OF HEPATITIS C VIRUS NS2
Descriptor:Protease NS2-3 (p23), B-OCTYLGLUCOSIDE, DECYL-BETA-D-MALTOPYRANOSIDE
Authors:Lorenz, I.C., Rice, C.M., Marcotrigiano, J.
Deposit date:2006-06-19
Release date:2006-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of the catalytic domain of the hepatitis C virus NS2-3 protease.
Nature, 442, 2006
4GUA
  • Download 4gua
  • View 4gua
Molmil generated image of 4gua
ALPHAVIRUS P23PRO-ZBD
Descriptor:Non-structural polyprotein, SULFATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Shin, G., Yost, S., Miller, M., Marcotrigiano, J.
Deposit date:2012-08-29
Release date:2012-10-03
Last modified:2012-10-24
Method:X-RAY DIFFRACTION (2.854 Å)
Cite:Structural and functional insights into alphavirus polyprotein processing and pathogenesis.
Proc.Natl.Acad.Sci.USA, 109, 2012
5E3H
  • Download 5e3h
  • View 5e3h
Molmil generated image of 5e3h
STRUCTURAL BASIS FOR RNA RECOGNITION AND ACTIVATION OF RIG-I
Descriptor:Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3'), ZINC ION, ...
Authors:Jiang, F., Miller, M.T., Marcotrigiano, J.
Deposit date:2015-10-02
Release date:2015-11-18
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of RNA recognition and activation by innate immune receptor RIG-I.
Nature, 479, 2011
5F98
  • Download 5f98
  • View 5f98
Molmil generated image of 5f98
CRYSTAL STRUCTURE OF RIG-I IN COMPLEX WITH CAP-0 RNA
Descriptor:Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP*UP*AP*UP*UP*AP*UP*AP*UP*UP*C)-3'), ZINC ION, ...
Authors:Wang, C., Marcotrigiano, J., Miller, M., Jiang, F.
Deposit date:2015-12-09
Release date:2016-01-13
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016
5F9F
  • Download 5f9f
  • View 5f9f
Molmil generated image of 5f9f
CRYSTAL STRUCTURE OF RIG-I HELICASE-RD IN COMPLEX WITH 24-MER BLUNT-END HAIRPIN RNA
Descriptor:Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP*UP*AP*UP*UP*AP*UP*AP*UP*UP*C)-3'), ZINC ION, ...
Authors:Wang, C., Marcotrigiano, J., Miller, M.T., Jiang, F.
Deposit date:2015-12-09
Release date:2016-01-13
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016
5F9H
  • Download 5f9h
  • View 5f9h
Molmil generated image of 5f9h
CRYSTAL STRUCTURE OF RIG-I HELICASE-RD IN COMPLEX WITH 24-MER 5' TRIPHOSPHATE HAIRPIN RNA
Descriptor:Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP*UP*AP*UP*UP*AP*UP*AP*UP*UP*C)-3'), ZINC ION, ...
Authors:Wang, C., Marcotrigiano, J., Miller, M., Jiang, F.
Deposit date:2015-12-09
Release date:2016-01-13
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016
5NPH
  • Download 5nph
  • View 5nph
Molmil generated image of 5nph
STRUCTURE OF THE HEPATITIS C VIRUS STRAIN J4 GLYCOPROTEIN E2 ANTIGENIC REGION 532-540 BOUND TO THE FAB FRAGMENT OF THE NON-NEUTRALIZING ANTIBODY DAO5
Descriptor:Genome polyprotein, Heavy chain of Fab fragment derived from non-neutralizing antibody DAO5, Light chain of Fab fragment derived from non-neutralizing antibody DAO5
Authors:Vasiliauskaite, I., Rey, F.A., Krey, T.
Deposit date:2017-04-16
Release date:2017-05-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2.
MBio, 8, 2017
5NPI
  • Download 5npi
  • View 5npi
Molmil generated image of 5npi
STRUCTURE OF THE HEPATITIS C VIRUS STRAIN J4 GLYCOPROTEIN E2 ANTIGENIC REGION 532-540 BOUND TO THE SINGLE CHAIN VARIABLE FRAGMENT OF THE NON-NEUTRALIZING ANTIBODY DAO5
Descriptor:Single chain variable fragment of the non-neutralizing antibody DAO5, Epitope peptide
Authors:Vasiliauskaite, I., Rey, F.A., Krey, T.
Deposit date:2017-04-16
Release date:2017-05-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2.
MBio, 8, 2017
5NPJ
  • Download 5npj
  • View 5npj
Molmil generated image of 5npj
STRUCTURE OF THE HEPATITIS C VIRUS STRAIN JFH1 GLYCOPROTEIN E2 ANTIGENIC REGION 532-540 BOUND TO THE SINGLE CHAIN VARIABLE FRAGMENT OF THE NON-NEUTRALIZING ANTIBODY DAO5
Descriptor:Single chain variable fragment of the non-neutralizing antibody DAO5, Epitope peptide
Authors:Vasiliauskaite, I., Rey, F.A., Krey, T.
Deposit date:2017-04-16
Release date:2017-05-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2.
MBio, 8, 2017