Author results

1GUL
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HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE
分子名称:GLUTATHIONE TRANSFERASE A4-4, S-(2-iodobenzyl) glutathione
著者Bruns, C.M., Hubatsch, I., Ridderstrom, M., Mannervik, B., Tainer, J.A.
登録日1998-06-10
公開日1999-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products
J.Mol.Biol., 288, 1999
1GUM
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HUMAN GLUTATHIONE TRANSFERASE A4-4 WITHOUT LIGANDS
分子名称:PROTEIN (GLUTATHIONE TRANSFERASE A4-4)
著者Bruns, C.M., Hubatsch, I., Ridderstrom, M., Mannervik, B., Tainer, J.A.
登録日1998-06-11
公開日1999-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products
J.Mol.Biol., 288, 1999
1EOG
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CRYSTAL STRUCTURE OF PI CLASS GLUTATHIONE TRANSFERASE
分子名称:GLUTATHIONE S-TRANSFERASE
著者Rossjohn, J., McKinstry, W.J., Oakley, A.J., Parker, M.W., Stenberg, G., Mannervik, B., Dragani, B., Cocco, R., Aceto, A.
登録日2000-03-22
公開日2000-10-18
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of thermolabile mutants of human glutathione transferase P1-1.
J.Mol.Biol., 302, 2000
1EOH
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GLUTATHIONE TRANSFERASE P1-1
分子名称:GLUTATHIONE S-TRANSFERASE
著者Rossjohn, J., McKinstry, W.J., Oakley, A.J., Parker, M.W., Stenberg, G., Mannervik, B., Dragani, B., Cocco, R., Aceto, A.
登録日2000-03-22
公開日2000-10-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of thermolabile mutants of human glutathione transferase P1-1.
J.Mol.Biol., 302, 2000
1MD3
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A FOLDING MUTANT OF HUMAN CLASS PI GLUTATHIONE TRANSFERASE, CREATED BY MUTATING GLYCINE 146 OF THE WILD-TYPE PROTEIN TO ALANINE
分子名称:pi glutathione transferase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE
著者Kong, G.K.-W., Dragani, B., Aceto, A., Cocco, R., Mannervik, B., Stenberg, G., McKinstry, W.J., Polekhina, G., Parker, M.W.
登録日2002-08-06
公開日2002-08-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1
J.Biol.Chem., 278, 2003
1MD4
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A FOLDING MUTANT OF HUMAN CLASS PI GLUTATHIONE TRANSFERASE, CREATED BY MUTATING GLYCINE 146 OF THE WILD-TYPE PROTEIN TO VALINE
分子名称:pi glutathione transferase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE
著者Kong, G.K.-W., Dragani, B., Aceto, A., Cocco, R., Mannervik, B., Stenberg, G., McKinstry, W.J., Polekhina, G., Parker, M.W.
登録日2002-08-06
公開日2002-08-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1
J.Biol.Chem., 278, 2003
1PKW
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE (GST) A1-1 IN COMPLEX WITH GLUTATHIONE
分子名称:Glutathione S-transferase A1, GLUTATHIONE, 2-HYDROXYETHYL DISULFIDE
著者Grahn, E., Jakobsson, E., Gustafsson, A., Grehn, L., Olin, B., Wahlberg, M., Madsen, D., Kleywegt, G.J., Mannervik, B.
登録日2003-06-06
公開日2004-06-22
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1PKZ
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE (GST) A1-1
分子名称:Glutathione S-transferase A1, 2-HYDROXYETHYL DISULFIDE
著者Grahn, E., Jakobsson, E., Gustafsson, A., Grehn, L., Olin, B., Wahlberg, M., Madsen, D., Kleywegt, G.J., Mannervik, B.
登録日2003-06-06
公開日2004-06-22
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1PL1
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE (GST) A1-1 IN COMPLEX WITH A DECARBOXY-GLUTATHIONE
分子名称:Glutathione S-transferase A1, CHLORIDE ION, N-(4-AMINOBUTANOYL)-S-(4-METHOXYBENZYL)-L-CYSTEINYLGLYCINE
著者Grahn, E., Jakobsson, E., Gustafsson, A., Grehn, L., Olin, B., Wahlberg, M., Madsen, D., Kleywegt, G.J., Mannervik, B.
登録日2003-06-06
公開日2004-06-22
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1PL2
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE (GST) A1-1 T68E MUTANT IN COMPLEX WITH DECARBOXY-GLUTATHIONE
分子名称:Glutathione S-transferase A1, CHLORIDE ION, N-(4-AMINOBUTANOYL)-S-(4-METHOXYBENZYL)-L-CYSTEINYLGLYCINE
著者Grahn, E., Jakobsson, E., Gustafsson, A., Grehn, L., Olin, B., Wahlberg, M., Madsen, D., Kleywegt, G.J., Mannervik, B.
登録日2003-06-06
公開日2004-06-22
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1PX6
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A FOLDING MUTANT OF HUMAN CLASS PI GLUTATHIONE TRANSFERASE, CREATED BY MUTATING ASPARTATE 153 OF THE WILD-TYPE PROTEIN TO ASPARAGINE
分子名称:Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE
著者Kong, G.K.-W., Polekhina, G., McKinstry, W.J., Parker, M.W., Dragani, B., Aceto, A., Paludi, D., Principe, D.R., Mannervik, B., Stenberg, G.
登録日2003-07-02
公開日2003-07-22
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The multi-functional role of a highly conserved aspartic acid residue in glutathione transferase P1-1
To be Published
1PX7
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A FOLDING MUTANT OF HUMAN CLASS PI GLUTATHIONE TRANSFERASE, CREATED BY MUTATING ASPARTATE 153 OF THE WILD-TYPE PROTEIN TO GLUTAMATE
分子名称:Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, ...
著者Kong, G.K.-W., Polekhina, G., McKinstry, W.J., Parker, M.W., Dragani, B., Aceto, A., Paludi, D., Principe, D.R., Mannervik, B., Stenberg, G.
登録日2003-07-02
公開日2003-07-22
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The multi-functional role of a highly conserved aspartic acid residue in glutathione transferase P1-1
To be Published
1QH3
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HUMAN GLYOXALASE II WITH CACODYLATE AND ACETATE IONS PRESENT IN THE ACTIVE SITE
分子名称:PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE), ZINC ION, CACODYLATE ION, ...
著者Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
登録日1999-05-10
公開日1999-09-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
1QH5
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HUMAN GLYOXALASE II WITH S-(N-HYDROXY-N-BROMOPHENYLCARBAMOYL)GLUTATHIONE
分子名称:PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE), ZINC ION, GLUTATHIONE, ...
著者Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
登録日1999-05-11
公開日1999-09-24
最終更新日2011-12-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
1QIN
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HUMAN GLYOXALASE I COMPLEXED WITH S-(N-HYDROXY-N-P-IODOPHENYLCARBAMOYL) GLUTATHIONE
分子名称:PROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-(N-HYDROXY-N-IODOPHENYLCARBAMOYL)GLUTATHIONE
著者Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
登録日1999-06-14
公開日1999-11-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
1QIP
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HUMAN GLYOXALASE I COMPLEXED WITH S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE
分子名称:PROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE, ...
著者Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
登録日1999-06-14
公開日1999-11-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
1XWG
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HUMAN GST A1-1 T68E MUTANT
分子名称:Glutathione S-transferase A1
著者Grahn, E., Jakobsson, E., Gustafsson, A., Novotny, M., Grehn, L., Olin, B., Madsen, D., Wahlberg, M., Mannervik, B., Kleywegt, G.J.
登録日2004-11-01
公開日2005-11-01
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
2C3N
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HUMAN GLUTATHIONE-S-TRANSFERASE T1-1, APO FORM
分子名称:GLUTATHIONE S-TRANSFERASE THETA 1, IODIDE ION
著者Tars, K., Larsson, A.-K., Shokeer, A., Olin, B., Mannervik, B., Kleywegt, G.J.
登録日2005-10-11
公開日2005-11-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2C3Q
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HUMAN GLUTATHIONE-S-TRANSFERASE T1-1 W234R MUTANT, COMPLEX WITH S- HEXYLGLUTATHIONE
分子名称:GLUTATHIONE S-TRANSFERASE THETA 1, S-HEXYLGLUTATHIONE, IODIDE ION
著者Tars, K., Larsson, A.-K., Shokeer, A., Olin, B., Mannervik, B., Kleywegt, G.J.
登録日2005-10-11
公開日2005-11-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2C3T
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HUMAN GLUTATHIONE-S-TRANSFERASE T1-1, W234R MUTANT, APO FORM
分子名称:GLUTATHIONE S-TRANSFERASE THETA 1
著者Tars, K., Larsson, A.-K., Shokeer, A., Olin, B., Mannervik, B., Kleywegt, G.J.
登録日2005-10-12
公開日2005-11-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2VCT
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GLUTATHIONE TRANSFERASE A2-2 IN COMPLEX WITH DELTA-4-ANDOSTRENE-3-17- DIONE
分子名称:GLUTATHIONE S-TRANSFERASE A2, 4-ANDROSTENE-3-17-DIONE
著者Tars, K., Olin, B., Mannervik, B.
登録日2007-09-27
公開日2008-10-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases.
J.Mol.Biol., 397, 2010
2VCV
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GLUTATHIONE TRANSFERASE A3-3 IN COMPLEX WITH GLUTATHIONE AND DELTA-4- ANDROSTENE-3-17-DIONE
分子名称:GLUTATHIONE S-TRANSFERASE A3, GLUTATHIONE, 4-ANDROSTENE-3-17-DIONE
著者Tars, K., Olin, B., Mannervik, B.
登録日2007-09-27
公開日2008-10-28
最終更新日2012-02-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases.
J.Mol.Biol., 397, 2010
2WJU
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GLUTATHIONE TRANSFERASE A2-2 IN COMPLEX WITH GLUTATHIONE
分子名称:GLUTATHIONE-S-TRANSFERASE A2-2, GLUTATHIONE
著者Tars, K., Olin, B., Mannervik, B.
登録日2009-05-29
公開日2009-06-09
最終更新日2012-02-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases.
J.Mol.Biol., 397, 2010
2C4J
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HUMAN GLUTATHIONE-S-TRANSFERASE M2-2 T210S MUTANT IN COMPLEX WITH GLUTATHIONE-STYRENE OXIDE CONJUGATE
分子名称:GLUTATHIONE S-TRANSFERASE MU 2, L-GAMMA-GLUTAMYL-S-[(2S)-2-HYDROXY-2-PHENYLETHYL]-L-CYSTEINYLGLYCINE
著者Tars, K., Andersson, M., Ivarsson, Y., Olin, B., Mannervik, B.
登録日2005-10-20
公開日2005-10-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Alternative Mutations of a Positively Selected Residue Elicit Gain or Loss of Functionalities in Enzyme Evolution.
Proc.Natl.Acad.Sci.USA, 103, 2006
2J9H
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE-S-TRANSFERASE P1-1 CYS-FREE MUTANT IN COMPLEX WITH S-HEXYLGLUTATHIONE AT 2.4 A RESOLUTION
分子名称:GLUTATHIONE S-TRANSFERASE P, S-HEXYLGLUTATHIONE
著者Tars, K., Hegazy, U.M., Hellman, U., Mannervik, B.
登録日2006-11-08
公開日2006-11-14
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Modulating Catalytic Activity by Unnatural Amino Acid Residues in a Gsh-Binding Loop of Gst P1-1.
J.Mol.Biol., 376, 2008
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