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1ALV
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BU of 1alv by Molmil
CALCIUM BOUND DOMAIN VI OF PORCINE CALPAIN
Descriptor: CALCIUM ION, CALPAIN
Authors:Narayana, S.V.L, Lin, G, Chattopadhyay, D, Maki, M.
Deposit date:1997-06-03
Release date:1998-06-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding.
Nat.Struct.Biol., 4, 1997
3AAJ
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BU of 3aaj by Molmil
Crystal structure of Ca2+-bound form of des3-23ALG-2deltaGF122
Descriptor: CALCIUM ION, Programmed cell death protein 6
Authors:Suzuki, H, Inuzuka, T, Kawasaki, M, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2009-11-19
Release date:2010-09-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition
Bmc Struct.Biol., 10, 2010
3AAK
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BU of 3aak by Molmil
Crystal structure of Zn2+-bound form of des3-20ALG-2F122A
Descriptor: Programmed cell death protein 6, ZINC ION
Authors:Inuzuka, T, Suzuki, H, Kawasaki, M, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2009-11-19
Release date:2010-09-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition
Bmc Struct.Biol., 10, 2010
1NX2
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BU of 1nx2 by Molmil
Calpain Domain VI
Descriptor: CALCIUM ION, Calcium-dependent protease, small subunit
Authors:Todd, B, Moore, D, Deivanayagam, C.C.S, Lin, G.-D, Chattopadhyay, D, Maki, M, Wang, K.K.W, Narayana, S.V.L.
Deposit date:2003-02-07
Release date:2003-08-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
J.Mol.Biol., 328, 2003
1NX1
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BU of 1nx1 by Molmil
Calpain Domain VI Complexed with Calpastatin Inhibitory Domain C (DIC)
Descriptor: CALCIUM ION, Calcium-dependent protease, small subunit, ...
Authors:Todd, B, Moore, D, Deivanayagam, C.C.S, Lin, G.-D, Chattopadhyay, D, Maki, M, Wang, K.K.W, Narayana, S.V.L.
Deposit date:2003-02-07
Release date:2003-08-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
J.Mol.Biol., 328, 2003
1NX0
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BU of 1nx0 by Molmil
Structure of Calpain Domain 6 in Complex with Calpastatin DIC
Descriptor: CALCIUM ION, Calcium-dependent protease, small subunit, ...
Authors:Todd, B, Moore, D, Deivanayagam, C.C.S, Lin, G.-D, Chattopadhyay, D, Maki, M, Wang, K.K.W, Narayana, S.V.L.
Deposit date:2003-02-07
Release date:2003-08-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
J.Mol.Biol., 328, 2003
1NX3
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BU of 1nx3 by Molmil
Calpain Domain VI in Complex with the Inhibitor PD150606
Descriptor: 3-(4-IODO-PHENYL)-2-MERCAPTO-PROPIONIC ACID, CALCIUM ION, Calcium-dependent protease, ...
Authors:Todd, B, Moore, D, Deivanayagam, C.C.S, Lin, G.-D, Chattopadhyay, D, Maki, M, Wang, K.K.W, Narayana, S.V.L.
Deposit date:2003-02-07
Release date:2003-08-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
J.Mol.Biol., 328, 2003
3WXA
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BU of 3wxa by Molmil
X-ray crystal structural analysis of the complex between ALG-2 and Sec31A peptide
Descriptor: Programmed cell death protein 6, Protein transport protein Sec31A, ZINC ION
Authors:Takahashi, T, Suzuki, H, Kawasaki, M, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2014-07-29
Release date:2015-03-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural Analysis of the Complex between Penta-EF-Hand ALG-2 Protein and Sec31A Peptide Reveals a Novel Target Recognition Mechanism of ALG-2
Int J Mol Sci, 16, 2015
2ZND
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BU of 2znd by Molmil
Crystal structure of Ca2+-free form of des3-20ALG-2
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, PHOSPHATE ION, Programmed cell death protein 6, ...
Authors:Suzuki, H, Kawasaki, M, Inuzuka, T, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2008-04-22
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism
Structure, 16, 2008
2ZN9
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BU of 2zn9 by Molmil
Crystal structure of Ca2+-bound form of des3-20ALG-2
Descriptor: CALCIUM ION, DODECAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, ...
Authors:Suzuki, H, Kawasaki, M, Inuzuka, T, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2008-04-22
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism
Structure, 16, 2008
2ZN8
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BU of 2zn8 by Molmil
Crystal structure of Zn2+-bound form of ALG-2
Descriptor: Programmed cell death protein 6, SODIUM ION, ZINC ION
Authors:Suzuki, H, Kawasaki, M, Inuzuka, T, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2008-04-22
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism
Structure, 16, 2008
2ZNE
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BU of 2zne by Molmil
Crystal structure of Zn2+-bound form of des3-23ALG-2 complexed with Alix ABS peptide
Descriptor: 16-meric peptide from Programmed cell death 6-interacting protein, Programmed cell death protein 6, SODIUM ION, ...
Authors:Suzuki, H, Kawasaki, M, Inuzuka, T, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2008-04-22
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism
Structure, 16, 2008
2ZRT
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BU of 2zrt by Molmil
Crystal structure of Zn2+-bound form of des3-23ALG-2
Descriptor: Programmed cell death protein 6, ZINC ION
Authors:Suzuki, H, Kawasaki, M, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2008-09-01
Release date:2008-11-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2
ACTA CRYSTALLOGR.,SECT.F, 64, 2008
2ZRS
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BU of 2zrs by Molmil
Crystal structure of Ca2+-bound form of des3-23ALG-2
Descriptor: CALCIUM ION, Programmed cell death protein 6
Authors:Suzuki, H, Kawasaki, M, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2008-09-01
Release date:2008-11-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2
ACTA CRYSTALLOGR.,SECT.F, 64, 2008
1ALW
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BU of 1alw by Molmil
INHIBITOR AND CALCIUM BOUND DOMAIN VI OF PORCINE CALPAIN
Descriptor: 3-(4-IODO-PHENYL)-2-MERCAPTO-PROPIONIC ACID, CALCIUM ION, CALPAIN
Authors:Narayana, S.V.L, Lin, G.
Deposit date:1997-06-04
Release date:1998-06-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding.
Nat.Struct.Biol., 4, 1997
1HAK
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BU of 1hak by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN PLACENTAL ANNEXIN V COMPLEXED WITH K-201 AS A CALCIUM CHANNEL ACTIVITY INHIBITOR
Descriptor: 4-[3-{1-(4-BENZYL)PIPERODINYL}PROPIONYL]-7-METHOXY-2,3,4,5-TERTRAHYDRO-1,4-BENZOTHIAZEPINE, ANNEXIN V
Authors:Ago, H, Inagaki, E, Miyano, M.
Deposit date:1997-12-10
Release date:1999-02-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of annexin V with its ligand K-201 as a calcium channel activity inhibitor.
J.Mol.Biol., 274, 1997
1DF0
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BU of 1df0 by Molmil
Crystal structure of M-Calpain
Descriptor: CALPAIN, M-CALPAIN
Authors:Hosfield, C.M, Elce, J.S, Davies, P.L, Jia, Z.
Deposit date:1999-11-16
Release date:2000-06-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation.
EMBO J., 18, 1999
3DF0
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BU of 3df0 by Molmil
Calcium-dependent complex between m-calpain and calpastatin
Descriptor: CALCIUM ION, Calpain small subunit 1, Calpain-2 catalytic subunit, ...
Authors:Moldoveanu, T, Gehring, K, Green, D.R.
Deposit date:2008-06-11
Release date:2008-11-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.
Nature, 456, 2008

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