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1O6Z
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1.95 A resolution structure of (R207S,R292S) mutant of malate dehydrogenase from the halophilic archaeon Haloarcula marismortui (holo form)
Descriptor: CHLORIDE ION, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Irimia, A, Ebel, C, Madern, D, Richard, S.B, Cosenza, L.W, Zaccai, G, Vellieux, F.M.D.
Deposit date:2002-10-22
Release date:2003-02-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Oligomeric States of Haloarcula Marismortui Malate Dehydrogenase are Modulated by Solvent Components as Shown by Crystallographic and Biochemical Studies
J.Mol.Biol., 326, 2003
8Q3C
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Structure of Selenomonas ruminantium lactate dehydrogenase I85R mutant
Descriptor: CHLORIDE ION, L-lactate dehydrogenase, NITRATE ION, ...
Authors:Bertrand, Q, Coquille, S, Iorio, A, Sterpone, F, Madern, D.
Deposit date:2023-08-03
Release date:2023-11-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases.
J.Struct.Biol., 215, 2023
1D3A
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BU of 1d3a by Molmil
CRYSTAL STRUCTURE OF THE WILD TYPE HALOPHILIC MALATE DEHYDROGENASE IN THE APO FORM
Descriptor: CHLORIDE ION, HALOPHILIC MALATE DEHYDROGENASE, SODIUM ION
Authors:Richard, S.B, Madern, D, Garcin, E, Zaccai, G.
Deposit date:1999-09-28
Release date:2000-03-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Halophilic adaptation: novel solvent protein interactions observed in the 2.9 and 2.6 A resolution structures of the wild type and a mutant of malate dehydrogenase from Haloarcula marismortui.
Biochemistry, 39, 2000
7Q3X
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Crystal structure of Malate dehydrogenase from Haloarcula marismortui with Potassium and Chloride ions
Descriptor: CHLORIDE ION, Malate dehydrogenase, POTASSIUM ION
Authors:Bertrand, Q, Roche, J, Girard, E, Madern, D.
Deposit date:2021-10-29
Release date:2022-02-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Resurrection of Ancestral Malate Dehydrogenases Reveals the Evolutionary History of Haloarchaeal Proteins.
To Be Published
5MF2
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Bacteriophage T5 distal tail protein pb9 co-crystallized with Tb-Xo4
Descriptor: CHLORIDE ION, Distal tail protein, TERBIUM(III) ION, ...
Authors:Engilberge, S, Riobe, F, Di Pietro, S, Lassalle, L, Arnaud, C.-A, Breyton, C, Madern, D, Coquelle, N, Maury, O, Girard, E.
Deposit date:2016-11-17
Release date:2017-09-20
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence.
Chem Sci, 8, 2017
8AB3
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Crystal Structure of the Lactate Dehydrogenase of Cyanobacterium Aponinum in complex with oxamate, NADH and FBP.
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1,6-di-O-phosphono-beta-D-fructofuranose, L-lactate dehydrogenase, ...
Authors:Robin, A.Y, Girard, E, Madern, D.
Deposit date:2022-07-04
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.616 Å)
Cite:Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery.
Mol.Biol.Evol., 40, 2023
8AB2
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Crystal Structure of the Lactate Dehydrogenase of Cyanobacterium Aponinum in its apo form.
Descriptor: 1,2-ETHANEDIOL, L-lactate dehydrogenase, TERBIUM(III) ION, ...
Authors:Robin, A.Y, Girard, E, Madern, D.
Deposit date:2022-07-04
Release date:2022-08-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery.
Mol.Biol.Evol., 40, 2023
4BGV
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BU of 4bgv by Molmil
1.8 A resolution structure of the malate dehydrogenase from Picrophilus torridus in its apo form
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Talon, R, Madern, D, Girard, E.
Deposit date:2013-03-28
Release date:2014-04-16
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.811 Å)
Cite:Insight Into Structural Evolution of Extremophilic Proteins
To be Published
4BGU
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1.50 A resolution structure of the malate dehydrogenase from Haloferax volcanii
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, ...
Authors:Talon, R, Madern, D, Girard, E.
Deposit date:2013-03-28
Release date:2014-04-16
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.487 Å)
Cite:Insight Into Structural Evolution of Extremophilic Proteins
To be Published
4CL3
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1.70 A resolution structure of the malate dehydrogenase from Chloroflexus aurantiacus
Descriptor: ACETATE ION, CADMIUM ION, CHLORIDE ION, ...
Authors:Talon, R, Madern, D, Girard, E.
Deposit date:2014-01-11
Release date:2014-02-05
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:An Experimental Point of View on Hydration/Solvation in Halophilic Proteins.
Front.Microbiol., 5, 2014
6H9S
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BU of 6h9s by Molmil
Crystal dimeric structure of Petrotoga mobilis lactate dehydrogenase with NADH
Descriptor: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Roche, J, Engilberge, S, Girard, E, Madern, D.
Deposit date:2018-08-06
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Petrotoga mobilis lactate dehydrogenase at 1.9 Angstrom resolution
To Be Published
6QSS
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BU of 6qss by Molmil
Crystal Structure of Ignicoccus islandicus malate dehydrogenase co-crystallized with 10 mM Tb-Xo4
Descriptor: CHLORIDE ION, Malate dehydrogenase, TERBIUM(III) ION, ...
Authors:Roche, J, Girard, E, Madern, D.
Deposit date:2019-02-21
Release date:2019-07-17
Last modified:2024-01-24
Method:SOLUTION SCATTERING (1.892 Å), X-RAY DIFFRACTION
Cite:The archaeal LDH-like malate dehydrogenase from Ignicoccus islandicus displays dual substrate recognition, hidden allostery and a non-canonical tetrameric oligomeric organization.
J.Struct.Biol., 208, 2019
7AOB
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Crystal structure of Thermaerobacter marianensis malate dehydrogenase
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Bertrand, Q, Lasalle, L, Girard, E, Madern, D.
Deposit date:2020-10-14
Release date:2020-10-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of Thermaerobacter marianensis malate dehydrogenase
To Be Published
7NAY
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BU of 7nay by Molmil
Crystal structure of lactate dehydrogenase from Selenomonas ruminantium with NADH.
Descriptor: 1,2-ETHANEDIOL, BORIC ACID, L-lactate dehydrogenase, ...
Authors:Bertrand, Q, Robin, A, Girard, E, Madern, D.
Deposit date:2021-01-25
Release date:2021-02-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases.
J.Struct.Biol., 215, 2023
2X0R
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R207S, R292S Mutant of Malate Dehydrogenase from the Halophilic Archeon Haloarcula marismortui (HoloForm)
Descriptor: CHLORIDE ION, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Irimia, A, Ebel, C, Vellieux, F.M.D, Richard, S.B, Cosenza, L.W, Zaccai, G, Madern, D.
Deposit date:2009-12-17
Release date:2009-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.915 Å)
Cite:The Oligomeric States of Haloarcula Marismortui Malate Dehydrogenase are Modulated by Solvent Components as Shown by Crystallographic and Biochemical Studies
J.Mol.Biol., 326, 2003
3NEP
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BU of 3nep by Molmil
1.55A resolution structure of malate dehydrogenase from Salinibacter ruber
Descriptor: Malate dehydrogenase
Authors:Coquelle, N, Madern, D.
Deposit date:2010-06-09
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Gradual adaptive changes of a protein facing high salt concentrations.
J.Mol.Biol., 404, 2010
2J5R
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BU of 2j5r by Molmil
2.25 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after second radiation burn (radiation damage series)
Descriptor: CHLORIDE ION, MALATE DEHYDROGENASE
Authors:Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M.
Deposit date:2006-09-19
Release date:2006-09-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
2J5Q
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2.15 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after first radiation burn (radiation damage series)
Descriptor: CHLORIDE ION, MALATE DEHYDROGENASE
Authors:Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M.
Deposit date:2006-09-19
Release date:2006-09-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
2J5K
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2.0 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui (radiation damage series)
Descriptor: CHLORIDE ION, MALATE DEHYDROGENASE
Authors:Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M.
Deposit date:2006-09-18
Release date:2006-09-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
2HLP
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BU of 2hlp by Molmil
CRYSTAL STRUCTURE OF THE E267R MUTANT OF A HALOPHILIC MALATE DEHYDROGENASE IN THE APO FORM
Descriptor: CHLORIDE ION, MALATE DEHYDROGENASE, SODIUM ION
Authors:Richard, S.B, Madern, D, Garcin, E, Zaccai, G.
Deposit date:1999-04-23
Release date:2000-02-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Halophilic adaptation: novel solvent protein interactions observed in the 2.9 and 2.6 A resolution structures of the wild type and a mutant of malate dehydrogenase from Haloarcula marismortui.
Biochemistry, 39, 2000
2X0J
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2.8 A RESOLUTION STRUCTURE OF MALATE DEHYDROGENASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH ETHENO-NAD
Descriptor: ETHENO-NAD, MALATE DEHYDROGENASE, SULFATE ION
Authors:Irimia, A, Madern, D, Zaccai, G, Vellieux, F.M, Karshikoff, A, Tibbelin, G, Ladenstein, R, Lien, T, Birkeland, N.K.
Deposit date:2009-12-14
Release date:2009-12-22
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (2.786 Å)
Cite:The 2.9A Resolution Crystal Structure of Malate Dehydrogenase from Archaeoglobus Fulgidus: Mechanisms of Oligomerisation and Thermal Stabilisation.
J.Mol.Biol., 335, 2004
2X0I
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2.9 A RESOLUTION STRUCTURE OF MALATE DEHYDROGENASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MALATE DEHYDROGENASE, SODIUM ION, ...
Authors:Irimia, A, Madern, D, Zaccai, G, Vellieux, F.M.D, Karshikoff, A, Tibbelin, G, Ladenstein, R, Lien, T, Birkeland, N.-K.
Deposit date:2009-12-14
Release date:2009-12-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:The 2.9A Resolution Crystal Structure of Malate Dehydrogenase from Archaeoglobus Fulgidus: Mechanisms of Oligomerisation and Thermal Stabilisation.
J.Mol.Biol., 335, 2004
3ZZN
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5-Mutant (R79W, R151A, E279A, E299A,E313A) Lactate-Dehydrogenase from Thermus thermophillus
Descriptor: ADENOSINE-5'-DIPHOSPHATE, LACTATE DEHYDROGENASE
Authors:Colletier, J.P, Mraihi, S, Madern, D.
Deposit date:2011-09-02
Release date:2012-02-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Sampling the conformational energy landscape of a hyperthermophilic protein by engineering key substitutions.
Mol. Biol. Evol., 29, 2012
2V65
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Apo LDH from the psychrophile C. gunnari
Descriptor: L-LACTATE DEHYDROGENASE A CHAIN
Authors:Coquelle, N, Madern, D, Vellieux, F.
Deposit date:2007-07-13
Release date:2007-09-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Activity, Stability and Structural Studies of Lactate Dehydrogenases Adapted to Extreme Thermal Environments.
J.Mol.Biol., 374, 2007
2X06
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SULFOLACTATE DEHYDROGENASE FROM METHANOCALDOCOCCUS JANNASCHII
Descriptor: L-SULFOLACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Irimia, A, Madern, D, Zaccai, G, Vellieux, F.M.D.
Deposit date:2009-12-07
Release date:2009-12-15
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Methanoarchaeal Sulfolactate Dehydrogenase: Prototype of a New Family of Nadh-Dependent Enzymes.
Embo J., 23, 2004

 

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