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6FL5
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BU of 6fl5 by Molmil
Structure of human SHMT1-H135N-R137A-E168N mutant at 3.6 Ang. resolution
Descriptor: CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, ...
Authors:Giardina, G, Cutruzzola, F, Lucchi, R.
Deposit date:2018-01-25
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.
FEBS J., 285, 2018

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