Author results

1GJE
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PEPTIDE ANTAGONIST OF IGFBP-1, MINIMIZED AVERAGE STRUCTURE
分子名称:IGFBP-1 antagonist
著者Lowman, H.B., Chen, Y.M., Skelton, N.J., Mortensen, D.L., Tomlinson, E.E., Sadick, M.D., Robinson, I.C., Clark, R.G.
登録日2001-05-11
公開日2001-05-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1IMW
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PEPTIDE ANTAGONIST OF IGFBP-1
分子名称:IGFBP-1 antagonist
著者Lowman, H.B., Chen, Y.M., Skelton, N.J., Mortensen, D.L., Tomlinson, E.E., Sadick, M.D., Robinson, I.C., Clark, R.G.
登録日2001-05-11
公開日2001-05-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1CZ8
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VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY
分子名称:Vascular endothelial growth factor A, LIGHT CHAIN OF NEUTRALIZING ANTIBODY, HEAVY CHAIN OF NEUTRALIZING ANTIBODY, ...
著者Chen, Y., Wiesmann, C., Fuh, G., Li, B., Christinger, H.W., McKay, P., de Vos, A.M., Lowman, H.B.
登録日1999-09-01
公開日2000-03-20
最終更新日2017-04-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
J.Mol.Biol., 293, 1999
1GJF
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PEPTIDE ANTAGONIST OF IGFBP1, (I,I+7) COVALENTLY RESTRAINED ANALOG, MINIMIZED AVERAGE STRUCTURE
分子名称:IGFBP-1 antagonist, PENTANE
著者Skelton, N.J., Chen, Y.M., Dubree, N., Quan, C., Jackson, D.Y., Cochran, A.G., Zobel, K., Deshayes, K., Baca, M., Pisabarro, M.T., Lowman, H.B.
登録日2001-05-11
公開日2001-05-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1GJG
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PEPTIDE ANTAGONIST OF IGFBP1, (I,I+8) COVALENTLY RESTRAINED ANALOG, MINIMIZED AVERAGE STRUCTURE
分子名称:IGFBP-1 antagonist, PENTANE
著者Skelton, N.J., Chen, Y.M., Dubree, N., Quan, C., Jackson, D.Y., Cochran, A.G., Zobel, K., Deshayes, K., Baca, M., Pisabarro, M.T., Lowman, H.B.
登録日2001-05-11
公開日2001-05-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1IN2
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PEPTIDE ANTAGONIST OF IGFBP1, (I,I+7) COVALENTLY RESTRAINED ANALOG
分子名称:IGFBP-1 antagonist, PENTANE
著者Skelton, N.J., Chen, Y.M., Dubree, N., Quan, C., Jackson, D.Y., Cochran, A.G., Zobel, K., Deshayes, K., Baca, M., Pisabarro, M.T., Lowman, H.B.
登録日2001-05-11
公開日2001-05-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1IN3
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PEPTIDE ANTAGONIST OF IGFBP1, (I,I+8) COVALENTLY RESTRAINED ANALOG
分子名称:IGFBP-1 antagonist, PENTANE
著者Skelton, N.J., Chen, Y.M., Dubree, N., Quan, C., Jackson, D.Y., Cochran, A.G., Zobel, K., Deshayes, K., Baca, M., Pisabarro, M.T., Lowman, H.B.
登録日2001-05-11
公開日2001-05-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1RPQ
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HIGH AFFINITY IGE RECEPTOR (ALPHA CHAIN) COMPLEXED WITH TIGHT-BINDING E131 'ZETA' PEPTIDE FROM PHAGE DISPLAY
分子名称:High affinity immunoglobulin epsilon receptor alpha-subunit precursor, Peptide E131, N-ACETYL-D-GLUCOSAMINE, ...
著者Stamos, J., Eigenbrot, C., Nakamura, G.R., Reynolds, M.E., Yin, J.P., Lowman, H.B., Fairbrother, W.J., Starovasnik, M.A.
登録日2003-12-03
公開日2004-07-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Convergent Recognition of the IgE Binding Site on the High-Affinity IgE Receptor.
Structure, 12, 2004
1ICW
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INTERLEUKIN-8, MUTANT WITH GLU 38 REPLACED BY CYS AND CYS 50 REPLACED BY ALA
分子名称:INTERLEUKIN-8
著者Eigenbrot, C., Lowman, H.B., Chee, L., Artis, D.R.
登録日1996-09-18
公開日1997-03-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural change and receptor binding in a chemokine mutant with a rearranged disulfide: X-ray structure of E38C/C50AIL-8 at 2 A resolution.
Proteins, 27, 1997
1JBF
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HAIRPIN PEPTIDE THAT INHIBITS IGE ACTIVITY BY BINDING TO THE HIGH AFFINITY IGE RECEPTOR
分子名称:IGE06
著者Nakamura, G.R., Starovasnik, M.A., Reynolds, M.E., Lowman, H.B.
登録日2001-06-04
公開日2001-08-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A novel family of hairpin peptides that inhibit IgE activity by binding to the high-affinity IgE receptor.
Biochemistry, 40, 2001
1KCN
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STRUCTURE OF E109 ZETA PEPTIDE, AN ANTAGONIST OF THE HIGH-AFFINITY IGE RECEPTOR
分子名称:e109 zeta peptide
著者Nakamura, G.R., Reynolds, M.E., Chen, Y.M., Starovasnik, M.A., Lowman, H.B.
登録日2001-11-09
公開日2002-03-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KCO
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STRUCTURE OF E131 ZETA PEPTIDE, A POTENT ANTAGONIST OF THE HIGH-AFFINITY IGE RECEPTOR
分子名称:e131 Zeta Peptide
著者Nakamura, G.R., Reynolds, M.E., Chen, Y.M., Starovasnik, M.A., Lowman, H.B.
登録日2001-11-09
公開日2002-03-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
1QE6
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INTERLEUKIN-8 WITH AN ADDED DISULFIDE BETWEEN RESIDUES 5 AND 33 (L5C/H33C)
分子名称:INTERLEUKIN-8 VARIANT, SULFATE ION
著者Gerber, N., Lowman, H., Artis, D.R., Eigenbrot, C.
登録日1999-07-13
公開日2000-03-22
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Receptor-binding conformation of the "ELR" motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 A resolution.
Proteins, 38, 2000
1BJ1
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VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH A NEUTRALIZING ANTIBODY
分子名称:Fab fragment, light chain, heavy chain, ...
著者Muller, Y.A., Christinger, H.W., De Vos, A.M.
登録日1998-06-30
公開日1999-01-13
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface.
Structure, 6, 1998
1HUW
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THE CRYSTAL STRUCTURE OF AFFINITY-MATURED HUMAN GROWTH HORMONE AT 2 ANGSTROMS RESOLUTION
分子名称:HUMAN GROWTH HORMONE
著者Ultsch, M.H., Somers, W.S., Kossiakoff, A.A., De Vos, A.M.
登録日1993-09-22
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of affinity-matured human growth hormone at 2 A resolution.
J.Mol.Biol., 236, 1994