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1GJE
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BU of 1gje by Molmil
Peptide Antagonist of IGFBP-1, Minimized Average Structure
Descriptor: IGFBP-1 antagonist
Authors:Lowman, H.B, Chen, Y.M, Skelton, N.J, Mortensen, D.L, Tomlinson, E.E, Sadick, M.D, Robinson, I.C, Clark, R.G.
Deposit date:2001-05-11
Release date:2001-05-30
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1IMW
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BU of 1imw by Molmil
Peptide Antagonist of IGFBP-1
Descriptor: IGFBP-1 antagonist
Authors:Lowman, H.B, Chen, Y.M, Skelton, N.J, Mortensen, D.L, Tomlinson, E.E, Sadick, M.D, Robinson, I.C, Clark, R.G.
Deposit date:2001-05-11
Release date:2001-05-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1GJG
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BU of 1gjg by Molmil
Peptide Antagonist of IGFBP1, (i,i+8) Covalently Restrained Analog, Minimized Average Structure
Descriptor: IGFBP-1 antagonist, PENTANE
Authors:Skelton, N.J, Chen, Y.M, Dubree, N, Quan, C, Jackson, D.Y, Cochran, A.G, Zobel, K, Deshayes, K, Baca, M, Pisabarro, M.T, Lowman, H.B.
Deposit date:2001-05-11
Release date:2001-05-30
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1GJF
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BU of 1gjf by Molmil
Peptide Antagonist of IGFBP1, (i,i+7) Covalently Restrained Analog, Minimized Average Structure
Descriptor: IGFBP-1 antagonist, PENTANE
Authors:Skelton, N.J, Chen, Y.M, Dubree, N, Quan, C, Jackson, D.Y, Cochran, A.G, Zobel, K, Deshayes, K, Baca, M, Pisabarro, M.T, Lowman, H.B.
Deposit date:2001-05-11
Release date:2001-05-30
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1RPQ
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BU of 1rpq by Molmil
High Affinity IgE Receptor (alpha chain) Complexed with Tight-Binding E131 'zeta' Peptide from Phage Display
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Stamos, J, Eigenbrot, C, Nakamura, G.R, Reynolds, M.E, Yin, J.P, Lowman, H.B, Fairbrother, W.J, Starovasnik, M.A.
Deposit date:2003-12-03
Release date:2004-07-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Convergent Recognition of the IgE Binding Site on the High-Affinity IgE Receptor.
Structure, 12, 2004
1CZ8
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BU of 1cz8 by Molmil
VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY
Descriptor: HEAVY CHAIN OF NEUTRALIZING ANTIBODY, LIGHT CHAIN OF NEUTRALIZING ANTIBODY, SULFATE ION, ...
Authors:Chen, Y, Wiesmann, C, Fuh, G, Li, B, Christinger, H.W, McKay, P, de Vos, A.M, Lowman, H.B.
Deposit date:1999-09-01
Release date:2000-03-20
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
J.Mol.Biol., 293, 1999
1IN2
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BU of 1in2 by Molmil
Peptide Antagonist of IGFBP1, (i,i+7) Covalently Restrained Analog
Descriptor: IGFBP-1 antagonist, PENTANE
Authors:Skelton, N.J, Chen, Y.M, Dubree, N, Quan, C, Jackson, D.Y, Cochran, A.G, Zobel, K, Deshayes, K, Baca, M, Pisabarro, M.T, Lowman, H.B.
Deposit date:2001-05-11
Release date:2001-05-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1IN3
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BU of 1in3 by Molmil
Peptide Antagonist of IGFBP1, (i,i+8) Covalently Restrained Analog
Descriptor: IGFBP-1 antagonist, PENTANE
Authors:Skelton, N.J, Chen, Y.M, Dubree, N, Quan, C, Jackson, D.Y, Cochran, A.G, Zobel, K, Deshayes, K, Baca, M, Pisabarro, M.T, Lowman, H.B.
Deposit date:2001-05-11
Release date:2001-05-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Biochemistry, 40, 2001
1KCN
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BU of 1kcn by Molmil
Structure of e109 Zeta Peptide, an Antagonist of the High-Affinity IgE Receptor
Descriptor: e109 zeta peptide
Authors:Nakamura, G.R, Reynolds, M.E, Chen, Y.M, Starovasnik, M.A, Lowman, H.B.
Deposit date:2001-11-09
Release date:2002-03-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KCO
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BU of 1kco by Molmil
Structure of e131 Zeta Peptide, a Potent Antagonist of the High-Affinity IgE Receptor
Descriptor: e131 Zeta Peptide
Authors:Nakamura, G.R, Reynolds, M.E, Chen, Y.M, Starovasnik, M.A, Lowman, H.B.
Deposit date:2001-11-09
Release date:2002-03-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
1ICW
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BU of 1icw by Molmil
INTERLEUKIN-8, MUTANT WITH GLU 38 REPLACED BY CYS AND CYS 50 REPLACED BY ALA
Descriptor: INTERLEUKIN-8
Authors:Eigenbrot, C, Lowman, H.B, Chee, L, Artis, D.R.
Deposit date:1996-09-18
Release date:1997-03-12
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural change and receptor binding in a chemokine mutant with a rearranged disulfide: X-ray structure of E38C/C50AIL-8 at 2 A resolution.
Proteins, 27, 1997
1JBF
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BU of 1jbf by Molmil
Hairpin Peptide that Inhibits IgE Activity by Binding to the High Affinity IgE Receptor
Descriptor: IGE06
Authors:Nakamura, G.R, Starovasnik, M.A, Reynolds, M.E, Lowman, H.B.
Deposit date:2001-06-04
Release date:2001-08-22
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:A novel family of hairpin peptides that inhibit IgE activity by binding to the high-affinity IgE receptor.
Biochemistry, 40, 2001
1BJ1
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BU of 1bj1 by Molmil
VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH A NEUTRALIZING ANTIBODY
Descriptor: Fab fragment, heavy chain, light chain, ...
Authors:Muller, Y.A, Christinger, H.W, De Vos, A.M.
Deposit date:1998-06-30
Release date:1999-01-13
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface.
Structure, 6, 1998
1QE6
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BU of 1qe6 by Molmil
INTERLEUKIN-8 WITH AN ADDED DISULFIDE BETWEEN RESIDUES 5 AND 33 (L5C/H33C)
Descriptor: INTERLEUKIN-8 VARIANT, SULFATE ION
Authors:Gerber, N, Lowman, H, Artis, D.R, Eigenbrot, C.
Deposit date:1999-07-13
Release date:2000-03-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Receptor-binding conformation of the "ELR" motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 A resolution.
Proteins, 38, 2000
1HUW
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BU of 1huw by Molmil
THE CRYSTAL STRUCTURE OF AFFINITY-MATURED HUMAN GROWTH HORMONE AT 2 ANGSTROMS RESOLUTION
Descriptor: HUMAN GROWTH HORMONE
Authors:Ultsch, M.H, Somers, W.S, Kossiakoff, A.A, De Vos, A.M.
Deposit date:1993-09-22
Release date:1994-01-31
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of affinity-matured human growth hormone at 2 A resolution.
J.Mol.Biol., 236, 1994

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