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Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor.
Descriptor:	(6S)-6-CYCLOPENTYL-6-[2-(3-FLUORO-4-ISOPROPOXYPHENYL)ETHYL]-4-HYDROXY-5,6-DIHYDRO-2H-PYRAN-2-ONE, HEPATITIS C VIRUS NS5B RNA POLYMERASE
Authors:	Li, H, Love, R.L.
Deposit date:	2006-06-12
Release date:	2006-09-05
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.58 Å)
Cite:	Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 16, 2006

Structure of catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor
Descriptor:	3-{1-[3-(DIMETHYLAMINO)PROPYL]-2-METHYL-1H-INDOL-3-YL}-4-(2-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, Protein Kinase C-beta II
Authors:	Grodsky, N.B, Love, R.L.
Deposit date:	2006-08-10
Release date:	2006-11-14
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Structure of the Catalytic Domain of Human Protein Kinase C beta II Complexed with a Bisindolylmaleimide Inhibitor Biochemistry, 45, 2006