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3HUS
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BU of 3hus by Molmil
Crystal structure of recombinant gamma N308K fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
Authors:Lord, S.T, Bowley, S.R, Okumura, N.
Deposit date:2009-06-15
Release date:2009-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Impaired protofibril formation in fibrinogen gammaN308K is due to altered D:D and "A:a" interactions.
Biochemistry, 48, 2009
1LTJ
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BU of 1ltj by Molmil
Crystal Structure of Recombinant Human Fibrinogen Fragment D with the Peptide Ligands Gly-Pro-Arg-Pro-Amide and Gly-His-Arg-Pro-Amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen Beta chain, ...
Authors:Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
Deposit date:2002-05-20
Release date:2002-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
Biochemistry, 41, 2002
1LT9
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BU of 1lt9 by Molmil
Crystal Structure of Recombinant Human Fibrinogen Fragment D
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
Authors:Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
Deposit date:2002-05-20
Release date:2002-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
Biochemistry, 41, 2002
3BVH
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BU of 3bvh by Molmil
Crystal Structure of Recombinant gammaD364A Fibrinogen Fragment D with the Peptide Ligand Gly-Pro-Arg-Pro-Amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-mer peptide GPRP, CALCIUM ION, ...
Authors:Bowley, S.R, Merenbloom, B.K, Betts, L, Okumura, N, Heroux, A, Gorkun, O.V, Lord, S.T.
Deposit date:2008-01-07
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic.
Biochemistry, 47, 2008
2OYI
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BU of 2oyi by Molmil
Crystal Structure of Fragment D of gammaD298,301A Fibrinogen with the Peptide Ligand Gly-Pro-Arg-Pro-Amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
Authors:Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
Deposit date:2007-02-22
Release date:2007-05-15
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Probing the gamma2 Calcium-Binding Site: Studies with gammaD298,301A Fibrinogen Reveal Changes in the gamma294-301 Loop that Alter the Integrity of the "a" Polymerization Site.
Biochemistry, 46, 2007
2OYH
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BU of 2oyh by Molmil
Crystal Structure of Fragment D of gammaD298,301A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-Amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
Authors:Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
Deposit date:2007-02-22
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the gamma2 Calcium-Binding Site: Studies with gammaD298,301A Fibrinogen Reveal Changes in the gamma294-301 Loop that Alter the Integrity of the "a" Polymerization Site.
Biochemistry, 46, 2007
3E1I
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BU of 3e1i by Molmil
Crystal Structure of BbetaD432A Variant Fibrinogen Fragment D with the Peptide Ligand Gly-His-Arg-Pro-amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
Authors:Bowley, S.R, Lord, S.T.
Deposit date:2008-08-04
Release date:2009-01-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fibrinogen variant BbetaD432A has normal polymerization but does not bind knob "B".
Blood, 113, 2009
1RE3
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BU of 1re3 by Molmil
Crystal Structure of Fragment D of BbetaD398A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-Amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
Authors:Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
Deposit date:2003-11-06
Release date:2004-05-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
Biochemistry, 43, 2004
1RF1
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BU of 1rf1 by Molmil
Crystal Structure of Fragment D of gammaE132A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
Authors:Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
Deposit date:2003-11-07
Release date:2004-03-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Calcium-Binding Site beta2, Adjacent to the "b" Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization.
Biochemistry, 43, 2004
1RE4
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BU of 1re4 by Molmil
Crystal Structure of Fragment D of BbetaD398A Fibrinogen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
Authors:Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
Deposit date:2003-11-06
Release date:2004-05-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
Biochemistry, 43, 2004
1RF0
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BU of 1rf0 by Molmil
Crystal Structure of Fragment D of gammaE132A Fibrinogen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
Authors:Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
Deposit date:2003-11-07
Release date:2004-03-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Calcium-Binding Site beta2, Adjacent to the "b" Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization.
Biochemistry, 43, 2004
2FFD
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BU of 2ffd by Molmil
Fibrinogen Fragment D with "A" knob peptide mimic GPRVVE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E Chain, ...
Authors:Betts, L.
Deposit date:2005-12-19
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:The structure of fibrinogen fragment D with the 'A' knob peptide GPRVVE.
THROMB.HAEMOST., 4, 2006
1YCP
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BU of 1ycp by Molmil
THE CRYSTAL STRUCTURE OF FIBRINOGEN-AA PEPTIDE 1-23 (F8Y) BOUND TO BOVINE THROMBIN EXPLAINS WHY THE MUTATION OF PHE-8 TO TYROSINE STRONGLY INHIBITS NORMAL CLEAVAGE AT ARGININE-16
Descriptor: ALPHA THROMBIN, EPSILON THROMBIN, FIBRINOPEPTIDE A-ALPHA
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1997-05-01
Release date:1998-05-06
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of fibrinogen-Aalpha peptide 1-23 (F8Y) bound to bovine thrombin explains why the mutation of Phe-8 to tyrosine strongly inhibits normal cleavage at Arg-16.
Biochem.J., 326, 1997

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