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6V1R
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BU of 6v1r by Molmil
Crystal structure of iAChSnFR Fluorescent Acetylcholine Sensor precursor binding protein
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ACETYLCHOLINE, DI(HYDROXYETHYL)ETHER, ...
Authors:Fan, C, Borden, P.M, Looger, L.L, Lester, H.A, Rees, D.C.
Deposit date:2019-11-21
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:A genetically encoded fluorescent sensor for in vivo acetylcholine detection
To Be Published
6URU
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BU of 6uru by Molmil
iAChSnFR Fluorescent Acetylcholine Sensor precursor
Descriptor: iAChSnFR precursor
Authors:Borden, P.M, Marvin, J.S, Looger, L.L.
Deposit date:2019-10-24
Release date:2019-11-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:iAChSnFR Fluorescent Acetylcholine Sensor precursor
To Be Published
3EK7
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BU of 3ek7 by Molmil
Calcium-saturated GCaMP2 dimer
Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
Authors:Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R.
Deposit date:2008-09-18
Release date:2008-12-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem., 284, 2009
3EKH
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BU of 3ekh by Molmil
Calcium-saturated GCaMP2 T116V/K378W mutant monomer
Descriptor: CALCIUM ION, GLYCEROL, Myosin light chain kinase, ...
Authors:Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R.
Deposit date:2008-09-19
Release date:2008-12-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem., 284, 2009
3EK4
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BU of 3ek4 by Molmil
Calcium-saturated GCaMP2 Monomer
Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
Authors:Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R.
Deposit date:2008-09-18
Release date:2008-12-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem., 284, 2009
3EK8
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BU of 3ek8 by Molmil
Calcium-saturated GCaMP2 T116V/G87R mutant monomer
Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
Authors:Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R.
Deposit date:2008-09-19
Release date:2008-12-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem., 284, 2009
3EKJ
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BU of 3ekj by Molmil
Calcium-free GCaMP2 (calcium binding deficient mutant)
Descriptor: Myosin light chain kinase, Green fluorescent protein, Calmodulin chimera
Authors:Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R.
Deposit date:2008-09-19
Release date:2008-12-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem., 284, 2009
6DGV
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BU of 6dgv by Molmil
iGABASnFR Fluorescent GABA Sensor precursor
Descriptor: Fluorescent GABA Sensor precursor
Authors:Marvin, J.S, Looger, L.L.
Deposit date:2018-05-18
Release date:2019-04-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A genetically encoded fluorescent sensor for in vivo imaging of GABA.
Nat.Methods, 16, 2019
4I2Y
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BU of 4i2y by Molmil
Crystal Structure of the genetically encoded calcium indicator RGECO1
Descriptor: CALCIUM ION, RGECO1
Authors:Akerboom, J, Looger, L.L, Schreiter, E.R.
Deposit date:2012-11-23
Release date:2013-07-24
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.
Front Mol Neurosci, 6, 2013
3OSR
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BU of 3osr by Molmil
Maltose-bound maltose sensor engineered by insertion of circularly permuted green fluorescent protein into E. coli maltose binding protein at position 311
Descriptor: Maltose-binding periplasmic protein,Green fluorescent protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Echevarria, I.M, Marvin, J.S, Looger, L.L, Schreiter, E.R.
Deposit date:2010-09-09
Release date:2011-10-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:A genetically encoded, high-signal-to-noise maltose sensor.
Proteins, 79, 2011
3OSQ
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BU of 3osq by Molmil
Maltose-bound maltose sensor engineered by insertion of circularly permuted green fluorescent protein into E. coli maltose binding protein at position 175
Descriptor: Maltose-binding periplasmic protein,Green fluorescent protein, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Echevarria, I.M, Marvin, J.S, Looger, L.L, Schreiter, E.R.
Deposit date:2010-09-09
Release date:2011-10-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A genetically encoded, high-signal-to-noise maltose sensor.
Proteins, 79, 2011
7S7U
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BU of 7s7u by Molmil
Crystal structure of iNicSnFR3a Fluorescent Nicotine Sensor with nicotine bound
Descriptor: iNicSnFR 3.0 Fluorescent Nicotine Sensor
Authors:Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C.
Deposit date:2021-09-17
Release date:2021-10-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands.
Elife, 11, 2022
7S7V
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BU of 7s7v by Molmil
Crystal structure of iNicSnFR3a Fluorescent Nicotine Sensor
Descriptor: iNicSnFR 3.0 Fluorescent Nicotine Sensor
Authors:Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C.
Deposit date:2021-09-17
Release date:2021-10-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands.
Elife, 11, 2022
7S7T
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BU of 7s7t by Molmil
iNicSnFR3a Nicotine Sensor comprising Periplasmic Binding sequence plus Fluorescent Sequence with varenicline bound
Descriptor: IODIDE ION, VARENICLINE, iNicSnFR 3.0 Fluorescent Nicotine Sensor
Authors:Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C.
Deposit date:2021-09-17
Release date:2021-10-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands.
Elife, 11, 2022
7ST4
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BU of 7st4 by Molmil
Calcium-saturated jGCaMP8.410.80
Descriptor: CALCIUM ION, GLYCEROL, L(+)-TARTARIC ACID, ...
Authors:Zhang, Y, Looger, L.L.
Deposit date:2021-11-11
Release date:2022-11-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Fast and sensitive GCaMP calcium indicators for imaging neural populations
Nature, 615, 2023
3SG7
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BU of 3sg7 by Molmil
Crystal Structure of GCaMP3-KF(linker 1)
Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
Authors:Schreiter, E.R, Akerboom, J, Looger, L.L.
Deposit date:2011-06-14
Release date:2012-06-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
3SG5
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BU of 3sg5 by Molmil
Crystal Structure of Dimeric GCaMP3-D380Y, QP(linker 1), LP(linker 2)
Descriptor: CALCIUM ION, GLYCEROL, Myosin light chain kinase, ...
Authors:Schreiter, E.R, Akerboom, J, Looger, L.L.
Deposit date:2011-06-14
Release date:2012-06-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
3SG3
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BU of 3sg3 by Molmil
Crystal Structure of GCaMP3-D380Y
Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
Authors:Schreiter, E.R, Akerboom, J, Looger, L.L.
Deposit date:2011-06-14
Release date:2012-06-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
3SG2
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BU of 3sg2 by Molmil
Crystal Structure of GCaMP2-T116V,D381Y
Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
Authors:Schreiter, E.R, Akerboom, J, Looger, L.L.
Deposit date:2011-06-14
Release date:2012-06-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
3SG6
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BU of 3sg6 by Molmil
Crystal Structure of Dimeric GCaMP2-LIA(linker 1)
Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
Authors:Schreiter, E.R, Akerboom, J, Looger, L.L.
Deposit date:2011-06-14
Release date:2012-06-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
3SG4
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BU of 3sg4 by Molmil
Crystal Structure of GCaMP3-D380Y, LP(linker 2)
Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
Authors:Schreiter, E.R, Akerboom, J, Looger, L.L.
Deposit date:2011-06-14
Release date:2012-06-20
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
3U0N
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BU of 3u0n by Molmil
Crystal structure of the engineered fluorescent protein mRuby, crystal form 2
Descriptor: SULFATE ION, mRuby
Authors:Akerboom, J, Looger, L.L, Schreiter, E.R.
Deposit date:2011-09-28
Release date:2012-10-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.
Front Mol Neurosci, 6, 2013
3U0K
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BU of 3u0k by Molmil
Crystal Structure of the genetically encoded calcium indicator RCaMP
Descriptor: ACETATE ION, CALCIUM ION, RCaMP
Authors:Akerboom, J, Looger, L.L, Schreiter, E.R.
Deposit date:2011-09-28
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.
Front Mol Neurosci, 6, 2013
3U0L
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BU of 3u0l by Molmil
Crystal structure of the engineered fluorescent protein mRuby, crystal form 1, pH 4.5
Descriptor: ACETATE ION, mRuby
Authors:Akerboom, J, Looger, L.L, Schreiter, E.R.
Deposit date:2011-09-28
Release date:2012-10-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.
Front Mol Neurosci, 6, 2013
3U0M
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BU of 3u0m by Molmil
Crystal structure of the engineered fluorescent protein mRuby, crystal form 1, pH 8.5
Descriptor: mRuby
Authors:Akerboom, J, Looger, L.L, Schreiter, E.R.
Deposit date:2011-09-28
Release date:2012-10-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.
Front Mol Neurosci, 6, 2013

 

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