Author results

5VEX
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STRUCTURE OF THE HUMAN GLP-1 RECEPTOR COMPLEX WITH NNC0640
分子名称:Glucagon-like peptide 1 receptor, Endolysin chimera, 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide
著者Song, G., Yang, D., Wang, Y., Graaf, C.D., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., Liu, D., Wu, F., Wu, Y., Zhao, S., Ye, L., Han, G.W., Lau, J., Wu, B., Hanson, M.A., Liu, Z.-J., Wang, M.-W., Stevens, R.C.
登録日2017-04-05
公開日2017-05-17
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
Nature, 546, 2017
5VEW
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STRUCTURE OF THE HUMAN GLP-1 RECEPTOR COMPLEX WITH PF-06372222
分子名称:Glucagon-like peptide 1 receptor,Endolysin chimera, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
著者Song, G., Yang, D., Wang, Y., Graaf, C.D., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., Liu, D., Wu, F., Wu, Y., Zhao, S., Ye, L., Han, G.W., Lau, J., Wu, B., Hanson, M.A., Liu, Z.-J., Wang, M.-W., Stevens, R.C.
登録日2017-04-05
公開日2017-05-24
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
Nature, 546, 2017
5UVM
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HIT FAMILY HYDROLASE FROM CLOSTRIDIUM THERMOCELLUM CTH-393
分子名称:Histidine triad (HIT) protein, ZINC ION, UNKNOWN ATOM OR ION, ...
著者Habel, J., Tempel, W., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2017-02-20
公開日2017-04-05
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献HIT family hydrolase from Clostridium thermocellum Cth-393
To Be Published
5K2D
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1.9A ANGSTROM A2A ADENOSINE RECEPTOR STRUCTURE WITH MR PHASING USING XFEL DATA
分子名称:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
著者Batyuk, A., Galli, L., Ishchenko, A., Han, G.W., Gati, C., Popov, P., Lee, M.-Y., Stauch, B., White, T.A., Barty, A., Aquila, A., Hunter, M.S., Liang, M., Boutet, S., Pu, M., Liu, Z.-J., Nelson, G., James, D., Li, C., Zhao, Y., Spence, J.C.H., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
登録日2016-05-18
公開日2016-09-21
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
5K2C
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1.9 ANGSTROM A2A ADENOSINE RECEPTOR STRUCTURE WITH SULFUR SAD PHASING AND PHASE EXTENSION USING XFEL DATA
分子名称:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
著者Batyuk, A., Galli, L., Ishchenko, A., Han, G.W., Gati, C., Popov, P., Lee, M.-Y., Stauch, B., White, T.A., Barty, A., Aquila, A., Hunter, M.S., Liang, M., Boutet, S., Pu, M., Liu, Z.-J., Nelson, G., James, D., Li, C., Zhao, Y., Spence, J.C.H., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
登録日2016-05-18
公開日2016-09-21
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
5K2B
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2.5 ANGSTROM A2A ADENOSINE RECEPTOR STRUCTURE WITH MR PHASING USING XFEL DATA
分子名称:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
著者Batyuk, A., Galli, L., Ishchenko, A., Han, G.W., Gati, C., Popov, P., Lee, M.-Y., Stauch, B., White, T.A., Barty, A., Aquila, A., Hunter, M.S., Liang, M., Boutet, S., Pu, M., Liu, Z.-J., Nelson, G., James, D., Li, C., Zhao, Y., Spence, J.C.H., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
登録日2016-05-18
公開日2016-09-21
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
5K2A
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2.5 ANGSTROM A2A ADENOSINE RECEPTOR STRUCTURE WITH SULFUR SAD PHASING USING XFEL DATA
分子名称:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
著者Batyuk, A., Galli, L., Ishchenko, A., Han, G.W., Gati, C., Popov, P., Lee, M.-Y., Stauch, B., White, T.A., Barty, A., Aquila, A., Hunter, M.S., Liang, M., Boutet, S., Pu, M., Liu, Z.-J., Nelson, G., James, D., Li, C., Zhao, Y., Spence, J.C.H., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
登録日2016-05-18
公開日2016-09-21
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
5H3K
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CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN FROM SYNECHOCYSTIS
分子名称:Slr0280 protein
著者Dong, L.-L., Wu, D.
登録日2016-10-25
公開日2017-10-25
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Crystal structure of a hypothetical protein from Synechocystis
To Be Published
5F9P
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CRYSTAL STRUCTURE STUDY OF ANTHRONE OXIDASE-LIKE PROTEIN
分子名称:Anthrone oxidase-like protein, GLYCEROL
著者Gao, X., Wu, D., Fan, K., Liu, Z.-J.
登録日2015-12-10
公開日2016-12-14
最終更新日2018-07-18
実験手法X-RAY DIFFRACTION (2.078 Å)
主引用文献Structure and Function of a C-C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis
ACS Chem. Biol., 12, 2017
5BPJ
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ALL THREE CA(2+)-BINDING LOOPS OF LIGHT-SENSITIVE CTENOPHORE PHOTOPROTEIN BEROVIN BIND MAGNESIUM IONS: THE SPATIAL STRUCTURE OF MG(2+)-LOADED APO-BEROVIN
分子名称:Apoberovin 1, MAGNESIUM ION
著者Burakova, L.P., Natashin, P.V., Malikova, N.P., Niu, F., Vysotski, E.S., Liu, Z.-J.
登録日2015-05-28
公開日2015-12-30
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (1.756 Å)
主引用文献All Ca(2+)-binding loops of light-sensitive ctenophore photoprotein berovin bind magnesium ions: The spatial structure of Mg(2+)-loaded apo-berovin.
J. Photochem. Photobiol. B, Biol., 154, 2016
4QGU
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PROTEIN DOMAIN COMPLEX WITH SSDNA
分子名称:Gamma-interferon-inducible protein 16, DNA (5'-D(P*AP*GP*GP*CP*CP*GP*GP*CP*GP*TP*GP*A)-3')
著者Ni, X., Ru, H., Zhao, L., Shaw, N., Ding, W., Songying, O., Liu, Z.-J.
登録日2014-05-25
公開日2015-06-17
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.545 Å)
主引用文献New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16.
J Mol Cell Biol, 8, 2016
4O8U
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STRUCTURE OF PF2046
分子名称:Uncharacterized protein PF2046
著者Su, J., Liu, Z.-J.
登録日2013-12-30
公開日2014-04-30
実験手法X-RAY DIFFRACTION (2.345 Å)
主引用文献Crystal structure of a novel non-Pfam protein PF2046 solved using low resolution B-factor sharpening and multi-crystal averaging methods
Protein Cell, 1, 2010
4M7R
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CRYSTAL STRUCTURE OF THE N-TERMINAL METHYLTRANSFERASE-LIKE DOMAIN OF ANAMORSIN
分子名称:Anamorsin, MERCURY (II) ION
著者Song, G., Liu, Z.-J.
登録日2013-08-12
公開日2013-10-30
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Crystal structure of the N-terminal methyltransferase-like domain of anamorsin
Proteins, 2013
4JBM
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STRUCTURE OF MURINE DNA BINDING PROTEIN BOUND WITH DS DNA
分子名称:Interferon-inducible protein AIM2, DNA (5'-D(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3')
著者Ru, H., Ni, X., Crowley, C., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.218 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBK
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MOLECULAR BASIS FOR ABROGATION OF ACTIVATION OF PRO-INFLAMMATORY CYTOKINES
分子名称:Interferon-activable protein 202, DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3')
著者Ru, H., Ni, X., Crowley, C., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.963 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBJ
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STRUCTURAL MIMICRY FOR FUNCTIONAL ANTAGONISM
分子名称:Interferon-activable protein 202
著者Ru, H., Ni, X., Ma, F., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.692 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4FC7
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STUDIES ON DCR SHED NEW LIGHT ON PEROXISOMAL BETA-OXIDATION: CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF PDCR
分子名称:Peroxisomal 2,4-dienoyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, COENZYME A
著者Hua, T., Wu, D., Wang, J., Shaw, N., Liu, Z.-J.
登録日2012-05-24
公開日2012-07-04
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal beta-oxidation of unsaturated fatty acids
J.Biol.Chem., 287, 2012
4FC6
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STUDIES ON DCR SHED NEW LIGHT ON PEROXISOMAL BETA-OXIDATION: CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF PDCR
分子名称:Peroxisomal 2,4-dienoyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, HEXANOYL-COENZYME A
著者Hua, T., Wu, D., Wang, J., Shaw, N., Liu, Z.-J.
登録日2012-05-24
公開日2012-07-04
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal beta-oxidation of unsaturated fatty acids
J.Biol.Chem., 287, 2012
4EF5
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CRYSTAL STRUCTURE OF STING CTD
分子名称:Transmembrane protein 173
著者Ouyang, S., Ru, H., Shaw, N., Jiang, Y., Niu, F., Zhu, Y., Qiu, W., Li, Y., Liu, Z.-J.
登録日2012-03-29
公開日2012-05-16
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4EF4
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CRYSTAL STRUCTURE OF STING CTD COMPLEX WITH C-DI-GMP
分子名称:Transmembrane protein 173, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION
著者Ouyang, S., Ru, H., Shaw, N., Jiang, Y., Niu, F., Zhu, Y., Qiu, W., Li, Y., Liu, Z.-J.
登録日2012-03-29
公開日2012-05-16
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4DKS
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A SPINDLE-SHAPED VIRUS PROTEIN (CHYMOTRYPSIN TREATED)
分子名称:Probable integrase
著者Ouyang, S., Liang, W., Huang, L., Liu, Z.-J.
登録日2012-02-04
公開日2012-05-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase
Acta Crystallogr.,Sect.D, 68, 2012
4B04
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN DUSP26 (C152S)
分子名称:DUAL SPECIFICITY PROTEIN PHOSPHATASE 26
著者Won, E.-Y., Lee, D.Y., Park, S.G., Yokoyama, S., Kim, S.J., Chi, S.-W.
登録日2012-06-28
公開日2013-05-29
最終更新日2013-06-05
実験手法X-RAY DIFFRACTION (2.205 Å)
主引用文献High-Resolution Crystal Structure of the Catalytic Domain of Human Dual-Specificity Phosphatase 26
Acta Crystallogr.,Sect.D, 69, 2013
3VCF
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SSV1 INTEGRASE C-TERMINAL CATALYTIC DOMAIN (174-335AA)
分子名称:Probable integrase
著者Ouyang, S., Liang, W., Huang, L., Liu, Z.-J.
登録日2012-01-04
公開日2012-05-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase
Acta Crystallogr.,Sect.D, 68, 2012
3UX9
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STRUCTURAL INSIGHTS INTO A HUMAN ANTI-IFN ANTIBODY EXERTING THERAPEUTIC POTENTIAL FOR SYSTEMIC LUPUS ERYTHEMATOSUS
分子名称:Interferon alpha-1/13, ScFv antibody
著者Ouyang, S., Zhao, L.X., Liang, W., Shaw, N., Liu, Z.-J., Liang, M.-F.
登録日2011-12-04
公開日2012-02-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
J.Mol.Med., 2012
3O2Y
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STRUCTURE-FUNCTION ANALYSIS OF HUMAN L-PROSTAGLANDIN D SYNTHASE BOUND WITH FATTY ACID
分子名称:Prostaglandin-H2 D-isomerase, OLEIC ACID, PALMITIC ACID, ...
著者Zhou, Y., Shaw, N., Li, Y., Zhao, Y., Zhang, R., Liu, Z.-J.
登録日2010-07-23
公開日2010-09-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid
To be Published