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6O8C
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CRYSTAL STRUCTURE OF STING CTT IN COMPLEX WITH TBK1
分子名称:Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide
著者Li, P., Zhao, B., Du, F.
登録日2019-03-09
公開日2019-05-22
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
6O8B
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CRYSTAL STRUCTURE OF STING CTD IN COMPLEX WITH TBK1
分子名称:Stimulator of interferon genes protein, Serine/threonine-protein kinase TBK1, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide
著者Li, P., Zhao, B., Du, F.
登録日2019-03-09
公開日2019-05-22
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
6O3N
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CROSS-ALPHA AMYLOID-LIKE STRUCTURE ALPHAAMA
分子名称:Cross-alpha Amyloid-like Structure alphaAmA
著者Zhang, S.-Q., Liu, L., DeGrado, W.F.
登録日2019-02-26
公開日2019-03-13
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Designed peptides that assemble into cross-alpha amyloid-like structures
Nat. Chem. Biol., 14, 2018
6NQD
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CRYO-EM STRUCTURE OF T/F100 SOSIP.664 HIV-1 ENV TRIMER IN COMPLEX WITH 8ANC195 FAB
分子名称:T/F100 Env gp120, T/F100 Env gp41, 8ANC195 G52K5 heavy chain, ...
著者Fang, Q., Rossmann, M.G.
登録日2019-01-21
公開日2019-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer.
Nat Commun, 10, 2019
6NN3
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STRUCTURE OF PARVOVIRUS B19 DECORATED WITH FAB MOLECULES FROM A HUMAN ANTIBODY
分子名称:VP2 of B19 parvovirus, Fab monoclonal antibody 860-55D, heavy chain, ...
著者Rossmann, M.G., Sun, Y., Klose, T., Liu, Y.
登録日2019-01-14
公開日2019-02-13
最終更新日2019-05-01
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structure of Parvovirus B19 Decorated by Fabs from a Human Antibody.
J. Virol., 93, 2019
6NHV
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SINGLE PARTICLE RECONSTRUCTION OF DARPIN AND ITS BOUND GFP ON A SYMMETRIC SCAFFOLD
分子名称:superfolder GFP, DARP14 - Subunit B, Subunit A-DARPin
著者Liu, Y., Huynh, D., Yeates, T.O.
登録日2018-12-24
公開日2019-05-08
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A 3.8 angstrom resolution cryo-EM structure of a small protein bound to an imaging scaffold.
Nat Commun, 10, 2019
6NHT
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SINGLE PARTICLE RECONSTRUCTION OF THE SYMMETRIC CORE AN ENGINEERED PROTEIN SCAFFOLD
分子名称:DARP14 - Subunit A with DARPin, DARP14 - Subunit B
著者Liu, Y., Huynh, D., Yeates, T.O.
登録日2018-12-23
公開日2019-05-08
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A 3.8 angstrom resolution cryo-EM structure of a small protein bound to an imaging scaffold.
Nat Commun, 10, 2019
6NCL
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NEAR-ATOMIC STRUCTURE OF ICOSAHEDRALLY AVERAGED PBCV-1 CAPSID
分子名称:P14, P9, P10, ...
著者Fang, Q., Rossmann, M.G.
登録日2018-12-11
公開日2019-01-30
最終更新日2019-02-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Near-atomic structure of a giant virus.
Nat Commun, 10, 2019
6MZM
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HUMAN TFIID BOUND TO PROMOTER DNA AND TFIIA
分子名称:Transcription initiation factor TFIID subunit 1, TAF1, Transcription initiation factor TFIID subunit 2, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZL
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HUMAN TFIID CANONICAL STATE
分子名称:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 3, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (23 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZI
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CRYOEM STRUCTURE OF HUMAN ENTEROVIRUS D68 EXPANDED 1 PARTICLE (PH 6.5, 4 DEGREES CELSIUS, 3 MIN)
分子名称:viral protein 1, viral protein 3, viral protein 2, ...
著者Liu, Y., Rossmann, M.G.
登録日2018-11-05
公開日2018-12-19
最終更新日2019-01-09
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MZD
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HUMAN TFIID LOBE A CANONICAL
分子名称:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 3, Transcription initiation factor TFIID subunit 4, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZC
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HUMAN TFIID BC CORE
分子名称:Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 4, Transcription initiation factor TFIID subunit 5, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MLC
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PHD6 DOMAIN OF MLL3 IN COMPLEX WITH HISTONE H4
分子名称:Histone-lysine N-methyltransferase 2C, Histone H4, ZINC ION, ...
著者Dong, A., Liu, Y., Qin, S., Lei, M., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2018-09-27
公開日2018-10-24
最終更新日2019-01-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.
Nat Commun, 10, 2019
6M98
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CRYSTAL STRUCTURE OF THE HIGH-AFFINITY COPPER TRANSPORTER CTR1 IN COMPLEX WITH CU(I)
分子名称:Chimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562, COPPER (I) ION, ZINC ION
著者Ren, F., Yuan, P.
登録日2018-08-22
公開日2019-04-03
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献X-ray structures of the high-affinity copper transporter Ctr1.
Nat Commun, 10, 2019
6M97
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CRYSTAL STRUCTURE OF THE HIGH-AFFINITY COPPER TRANSPORTER CTR1
分子名称:Chimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562, HEXATANTALUM DODECABROMIDE, ZINC ION
著者Ren, F., Yuan, P.
登録日2018-08-22
公開日2019-04-03
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献X-ray structures of the high-affinity copper transporter Ctr1.
Nat Commun, 10, 2019
6JU3
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO CRNA PROMOTER IN CLASS 2
分子名称:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
著者Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
登録日2019-04-12
公開日2019-06-12
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insight into RNA synthesis by influenza D polymerase
To Be Published
6JU2
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO CRNA PROMOTER IN CLASS 1
分子名称:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
著者Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
登録日2019-04-12
公開日2019-06-12
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Structural insight into RNA synthesis by influenza D polymerase
To Be Published
6J0Z
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CRYSTAL STRUCTURE OF ALPK
分子名称:Putative angucycline-like polyketide oxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Wang, W., Liu, Y., Liang, H.
登録日2018-12-27
公開日2019-03-06
実験手法X-RAY DIFFRACTION (2.889 Å)
主引用文献Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin
Biochem. Biophys. Res. Commun., 510, 2019
6IXM
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CRYSTAL STRUCTURE OF THE KETONE REDUCTASE CHKRED20 FROM THE GENOME OF CHRYSEOBACTERIUM SP. CA49 COMPLEXED WITH NAD
分子名称:Short-chain dehydrogenase reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Zhao, F.J., Jin, Y., Liu, Z.C., Wang, G.G., Wu, Z.L.
登録日2018-12-11
公開日2019-04-03
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structure-guided engineering of ChKRED20 from Chryseobacterium sp. CA49 for asymmetric reduction of aryl ketoesters.
Enzyme Microb. Technol., 125, 2019
6IQD
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CRYSTAL STRUCTURE OF ALCOHOL DEHYDROGENASE FROM GEOBACILLUS STEAROTHERMOPHILUS
分子名称:Alcohol dehydrogenase, ZINC ION
著者Xue, S., Feng, Y., Guo, X., Zhao, Z.
登録日2018-11-07
公開日2019-06-05
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Characterization of the substrate scope of an alcohol dehydrogenase commonly used as methanol dehydrogenase.
Bioorg.Med.Chem.Lett., 29, 2019
6IH8
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CRYSTAL STRUCTURE OF PHOSPHITE DEHYDROGENASE MUTANT I151R/P176R/M207A FROM RALSTONIA SP. 4506
分子名称:Phosphite dehydrogenase
著者Song, X., Feng, Y., Liu, Y., Zhao, Z.
登録日2018-09-28
公開日2019-03-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9, 2019
6IH6
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PHOSPHITE DEHYDROGENASE MUTANT I151R/P176R/M207A FROM RALSTONIA SP. 4506 IN COMPLEX WITH NON-NATURAL COFACTOR NICOTINAMIDE CYTOSINE DINUCLEOTIDE
分子名称:Phosphite dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate
著者Song, X., Feng, Y., Liu, Y., Zhao, Z.
登録日2018-09-28
公開日2019-03-13
実験手法X-RAY DIFFRACTION (2.491 Å)
主引用文献Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9, 2019
6IH5
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CRYSTAL STRUCTURE OF PHOSPHITE DEHYDROGENASE MUTANT I151R/P176E FROM RALSTONIA SP. 4506 IN COMPLEX WITH NON-NATURAL COFACTOR NICOTINAMIDE CYTOSINE DINUCLEOTIDE
分子名称:Phosphite dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate
著者Song, X., Feng, Y., Liu, Y., Zhao, Z.
登録日2018-09-28
公開日2019-03-13
実験手法X-RAY DIFFRACTION (2.468 Å)
主引用文献Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9, 2019
6IH4
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CRYSTAL STRUCTURE OF PHOSPHITE DEHYDROGENASE MUTANT I151R/P176E FROM RALSTONIA SP. 4506
分子名称:Phosphite dehydrogenase
著者Song, X., Feng, Y., Liu, Y., Zhao, Z.
登録日2018-09-28
公開日2019-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9, 2019