Author results

4UX5
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STRUCTURE OF DNA COMPLEX OF PCG2
Descriptor:TRANSCRIPTION FACTOR MBP1, 5'-D(*CP*AP*AP*TP*GP*AP*CP*GP*CP*GP*TP*AP*AP*GP)-3', 5'-D(*CP*TP*TP*AP*CP*GP*CP*GP*TP*CP*AP*TP*TP*GP)-3'
Authors:Liu, J., Huang, J., Zhao, Y., Liu, H., Wang, D., Yang, J., Zhao, W., Taylor, I.A., Peng, Y.
Deposit date:2014-08-19
Release date:2015-01-14
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of DNA Recognition by Pcg2 Reveals a Novel DNA Binding Mode for Winged Helix-Turn-Helix Domains.
Nucleic Acids Res., 43, 2015
5YJ8
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IDENTIFICATION OF A SMALL MOLECULE INHIBITOR FOR THE TUDOR DOMAIN OF TDRD3
Descriptor:Tudor domain-containing protein 3, 5-(aminomethyl)-1,3-dimethyl-benzimidazol-2-one, SULFATE ION
Authors:Liu, J., Ruan, K.
Deposit date:2017-10-09
Release date:2018-05-02
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:Structural plasticity of the TDRD3 Tudor domain probed by a fragment screening hit.
FEBS J., 285, 2018
5GP0
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CRYSTAL STRUCTURE OF GERANIOL-NUDX1 COMPLEX
Descriptor:Nudix hydrolase 1, GLYCEROL, GERANYL DIPHOSPHATE
Authors:Liu, J., Guan, Z., Zou, T., Yin, P.
Deposit date:2016-07-30
Release date:2017-10-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis.
Mol Plant, 11, 2018
5WWD
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CRYSTAL STRUCTURE OF ATNUDX1
Descriptor:Nudix hydrolase 1, GLYCEROL, METHOXYETHANE, ...
Authors:Liu, J., Guan, Z., Yan, L., Zou, T., Yin, P.
Deposit date:2016-12-31
Release date:2017-11-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.386 Å)
Cite:Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis.
Mol Plant, 11, 2018
5WY6
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CRYSTAL STRUCTURE OF ATNUDX1 (E56A)
Descriptor:Nudix hydrolase 1, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Liu, J., Guan, Z., Yan, L., Zou, T., Yin, P.
Deposit date:2017-01-11
Release date:2017-11-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.779 Å)
Cite:Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis.
Mol Plant, 11, 2018
1JCC
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CRYSTAL STRUCTURE OF A NOVEL ALANINE-ZIPPER TRIMER AT 1.7 A RESOLUTION, V13A,L16A,V20A,L23A,V27A,M30A,V34A MUTATIONS
Descriptor:MAJOR OUTER MEMBRANE LIPOPROTEIN, ZINC ION
Authors:Liu, J., Dai, J., Lu, M.
Deposit date:2001-06-08
Release date:2003-06-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Zinc-Mediated Helix Capping in A Triple-Helical Protein
Biochemistry, 42, 2003
1STZ
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CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN AT 2.2 A RESOLUTION
Descriptor:Heat-inducible transcription repressor hrcA homolog
Authors:Liu, J., Adams, P.D., Shin, D.-H., Huang, C., Yokota, H., Jancarik, J., Kim, R., Kim, S.-H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-03-25
Release date:2004-08-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a heat-inducible transcriptional repressor HrcA from Thermotoga maritima: structural insight into DNA binding and dimerization.
J.Mol.Biol., 350, 2005
1SU0
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CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN AT 2.3 A RESOLUTION
Descriptor:NifU like protein IscU, ZINC ION
Authors:Liu, J., Oganesyan, N., Shin, D.-H., Jancarik, J., Pufan, R., Yokota, H., Kim, R., Kim, S.-H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-03-25
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural characterization of an iron-sulfur cluster assembly protein IscU in a zinc-bound form.
Proteins, 59, 2005
2L3T
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SOLUTION STRUCTURE OF TANDEM SH2 DOMAIN FROM SPT6
Descriptor:Transcription elongation factor SPT6
Authors:Liu, J., Zhang, J., Wu, J., Shi, Y.
Deposit date:2010-09-22
Release date:2011-06-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the tandem SH2 domains from Spt6 and their binding to the phosphorylated RNA polymerase II C-terminal domain
To be Published
2LKO
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STRUCTURAL BASIS OF PHOSPHOINOSITIDE BINDING TO KINDLIN-2 PLECKSTRIN HOMOLOGY DOMAIN IN REGULATING INTEGRIN ACTIVATION
Descriptor:Fermitin family homolog 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE
Authors:Liu, J., Fukuda, K., Xu, Z.
Deposit date:2011-10-17
Release date:2011-10-26
Last modified:2011-12-28
Method:SOLUTION NMR
Cite:Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation.
J.Biol.Chem., 286, 2011
2MTP
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THE STRUCTURE OF FILAMIN REPEAT 21 BOUND TO INTEGRIN
Descriptor:Filamin-A, Integrin alpha-IIb, Integrin beta-3
Authors:Liu, J., Qin, J.
Deposit date:2014-08-28
Release date:2015-04-01
Last modified:2015-07-01
Method:SOLUTION NMR
Cite:Structural mechanism of integrin inactivation by filamin.
Nat.Struct.Mol.Biol., 22, 2015
3C2G
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CRYSTAL COMPLEX OF SYS-1/POP-1 AT 2.5A RESOLUTION
Descriptor:Sys-1 protein, Pop-1 8-residue peptide
Authors:Liu, J., Phillips, B.T., Amaya, M.F., Kimble, J., Xu, W.
Deposit date:2008-01-24
Release date:2008-05-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The C. elegans SYS-1 protein is a bona fide beta-catenin.
Dev.Cell, 14, 2008
3C2H
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CRYSTAL STRUCTURE OF SYS-1 AT 2.6A RESOLUTION
Descriptor:Sys-1 protein, CITRATE ANION, GLYCEROL
Authors:Liu, J., Phillips, B.T., Amaya, M.F., Kimble, J., Xu, W.
Deposit date:2008-01-25
Release date:2008-05-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The C. elegans SYS-1 protein is a bona fide beta-catenin.
Dev.Cell, 14, 2008
3I6G
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NEWLY IDENTIFIED EPITOPE MN2 FROM SARS-COV M PROTEIN COMPLEXED WITHHLA-A*0201
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Liu, J.
Deposit date:2009-07-07
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes.
J.INFECT.DIS., 202, 2010
3I6K
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NEWLY IDENTIFIED EPITOPE FROM SARS-COV MEMBRANE PROTEIN COMPLEXED WITH HLA-A*0201
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Liu, J., Sun, Y., Qi, J., Chu, F., Wu, H., Gao, F., Li, T., Yan, J., Gao, G.F.
Deposit date:2009-07-07
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202, 2010
3J3R
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2014-10-22
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
3J3S
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2015-01-21
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3T
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2015-01-21
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3U
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2015-01-21
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3TCP
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTO-ONCOGENE TYROSINE-PROTEIN KINASE MER IN COMPLEX WITH INHIBITOR UNC569
Descriptor:Tyrosine-protein kinase Mer, 1-[(trans-4-aminocyclohexyl)methyl]-N-butyl-3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine, CHLORIDE ION, ...
Authors:Liu, J., Yang, C., Simpson, C., DeRyckere, D., Van Deusen, A., Miley, M., Kireev, D.B., Norris-Drouin, J., Sather, S., Hunter, D., Patel, H.S., Janzen, W.P., Machius, M., Johnson, G., Earp, H.S., Graham, D.K., Frye, S., Wang, X.
Deposit date:2011-08-09
Release date:2012-06-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia.
ACS Med Chem Lett, 3, 2012
3TO2
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STRUCTURE OF HLA-A*0201 COMPLEXED WITH PEPTIDE MD3-C9 DERIVED FROM A CLUSTERING REGION OF RESTRICTED CYTOTOXIC T LYMPHOCYTE EPITOPE FROM SARS-COV M PROTEIN
Descriptor:MHC class I antigen, Beta-2-microglobulin, Md3-C9 peptide derived from Membrane glycoprotein
Authors:Liu, J., Qi, J., Gao, F., Yan, J., Gao, G.F.
Deposit date:2011-09-03
Release date:2012-08-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Functional and Structural Definition of a Clustering Region of HLA-A2-restricted Cytotoxic T Lymphocyte Epitopes
Sci.Technology Rev., 29, 2011
4DFH
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CRYSTAL STRUCTURE OF CELL ADHESION MOLECULE NECTIN-2/CD112 VARIABLE DOMAIN
Descriptor:Poliovirus receptor-related protein 2
Authors:Liu, J., Qian, X., Chen, Z., Xu, X., Gao, F., Zhang, S., Zhang, R., Qi, J., Gao, G.F., Yan, J.
Deposit date:2012-01-23
Release date:2012-06-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
4DFI
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CRYSTAL STRUCTURE OF CELL ADHESION MOLECULE NECTIN-2/CD112 MUTANT FAMP
Descriptor:Poliovirus receptor-related protein 2
Authors:Liu, J., Qian, X., Chen, Z., Xu, X., Gao, F., Zhang, S., Zhang, R., Qi, J., Gao, G.F., Yan, J.
Deposit date:2012-01-23
Release date:2012-06-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
4F7M
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CRYSTAL STRUCTURE OF HLA-A*2402 COMPLEXED WITH A NEWLY IDENTIFIED PEPTIDE FROM 2009 H1N1 PA (649-658)
Descriptor:HLA class I histocompatibility antigen, A-24 alpha chain, Beta-2-microglobulin, ...
Authors:Liu, J., Zhang, S., Tan, S., Yi, Y., Wu, B., Zhu, F., Wang, H., Qi, J., George, F.G.
Deposit date:2012-05-16
Release date:2012-10-10
Last modified:2012-12-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
4F7P
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CRYSTAL STRUCTURE OF HLA-A*2402 COMPLEXED WITH A NEWLY IDENTIFIED PEPTIDE FROM 2009H1N1 PB1 (496-505)
Descriptor:HLA class I histocompatibility antigen, A-24 alpha chain, Beta-2-microglobulin, ...
Authors:Liu, J., Zhang, S., Tan, S., Yi, Y., Wu, B., Zhu, F., Wang, H., Qi, J., Gao, G.F.
Deposit date:2012-05-16
Release date:2012-10-10
Last modified:2012-12-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012