Author results

1NY7
  • Download 1ny7
  • View 1ny7
Molmil generated image of 1ny7
COWPEA MOSAIC VIRUS (CPMV)
Descriptor:COWPEA MOSAIC VIRUS, SMALL (S) SUBUNIT, LARGE (L) SUBUNIT
Authors:Lin, T., Chen, Z., Usha, R., Stauffacher, C.V., Dai, J.-B., Schmidt, T., Johnson, J.E.
Deposit date:2003-02-11
Release date:2003-03-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Refined Crystal Structure of Cowpea Mosaic Virus at 2.8A Resolution
Virology, 265, 1999
1PGL
  • Download 1pgl
  • View 1pgl
Molmil generated image of 1pgl
BEAN POD MOTTLE VIRUS (BPMV), MIDDLE COMPONENT
Descriptor:5'-R(*AP*GP*UP*CP*UP*C)-3', BEAN POD MOTTLE VIRUS SMALL (S) SUBUNIT, BEAN POD MOTTLE VIRUS LARGE (L) SUBUNIT
Authors:Lin, T., Cavarelli, J., Johnson, J.E.
Deposit date:2003-05-28
Release date:2003-11-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus.
Virology, 314, 2003
1PGW
  • Download 1pgw
  • View 1pgw
Molmil generated image of 1pgw
BEAN POD MOTTLE VIRUS (BPMV), TOP COMPONENT
Descriptor:BEAN POD MOTTLE VIRUS SMALL (S) SUBUNIT, BEAN POD MOTTLE VIRUS LARGE (L) SUBUNIT
Authors:Lin, T., Cavarelli, J., Johnson, J.E.
Deposit date:2003-05-28
Release date:2003-11-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus.
Virology, 314, 2003
3V3E
  • Download 3v3e
  • View 3v3e
Molmil generated image of 3v3e
CRYSTAL STRUCTURE OF THE HUMAN NUR77 LIGAND-BINDING DOMAIN
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Zhang, Q., Shi, C., Yang, K., Chen, Y., Zhan, Y., Wu, Q., Lin, T.
Deposit date:2011-12-13
Release date:2012-09-26
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
Nat.Chem.Biol., 8, 2012
3V3Q
  • Download 3v3q
  • View 3v3q
Molmil generated image of 3v3q
CRYSTAL STRUCTURE OF HUMAN NUR77 LIGAND-BINDING DOMAIN IN COMPLEX WITH ETHYL 2-[2,3,4 TRIMETHOXY-6(1-OCTANOYL)PHENYL]ACETATE
Descriptor:Nuclear receptor subfamily 4 group A member 1, ethyl (2,3,4-trimethoxy-6-octanoylphenyl)acetate, GLYCEROL, ...
Authors:Zhang, Q., Shi, C., Yang, K., Chen, Y., Zhan, Y., Wu, Q., Lin, T.
Deposit date:2011-12-14
Release date:2012-09-26
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
Nat.Chem.Biol., 8, 2012
1F2N
  • Download 1f2n
  • View 1f2n
Molmil generated image of 1f2n
RICE YELLOW MOTTLE VIRUS
Descriptor:CAPSID PROTEIN, CALCIUM ION
Authors:Qu, C., Liljas, L., Opalka, N., Brugidou, C., Yeager, M., Beachy, R.N., Fauquet, C.M., Johnson, J.E., Lin, T.
Deposit date:2000-05-26
Release date:2000-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:3D domain swapping modulates the stability of members of an icosahedral virus group.
Structure Fold.Des., 8, 2000
1F8V
  • Download 1f8v
  • View 1f8v
Molmil generated image of 1f8v
THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA
Descriptor:RNA, MATURE CAPSID PROTEIN BETA, MATURE CAPSID PROTEIN GAMMA, ...
Authors:Tang, L., Johnson, K.N., Ball, L.A., Lin, T., Yeager, M., Johnson, J.E.
Deposit date:2000-07-05
Release date:2000-12-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of pariacoto virus reveals a dodecahedral cage of duplex RNA.
Nat.Struct.Biol., 8, 2001
2BFU
  • Download 2bfu
  • View 2bfu
Molmil generated image of 2bfu
X-RAY STRUCTURE OF CPMV TOP COMPONENT
Descriptor:COWPEA MOSAIC VIRUS, LARGE (L) SUBUNIT, SMALL (S) SUBUNIT
Authors:Ochoa, W.F., Chatterji, A., Lin, T., Johnson, J.E.
Deposit date:2004-12-13
Release date:2005-01-12
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (4 Å)
Cite:Generation and Structural Analysis of Reactive Empty Particles Derived from an Icosahedral Virus.
Chem.Biol., 13, 2006
2JZI
  • Download 2jzi
  • View 2jzi
Molmil generated image of 2jzi
STRUCTURE OF CALMODULIN COMPLEXED WITH THE CALMODULIN BINDING DOMAIN OF CALCINEURIN
Descriptor:Calmodulin, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CALCIUM ION
Authors:Chyan, C., Huang, J., Irene, D., Lin, T.
Deposit date:2008-01-09
Release date:2009-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of Calmodulin complexed with the Calmodulin Binding Domain of Calcineurin
To be Published
4FVB
  • Download 4fvb
  • View 4fvb
Molmil generated image of 4fvb
CRYSTAL STRUCTURE OF EV71 2A PROTEINASE C110A MUTANT
Descriptor:2A proteinase, ZINC ION
Authors:Cai, Q., Muhammad, Y., Liu, W., Gao, Z., Peng, X., Cai, Y., Wu, C., Zheng, Q., Li, J., Lin, T.
Deposit date:2012-06-29
Release date:2013-06-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational Plasticity of 2A Proteinase from Enterovirus 71
J.Virol., 87, 2013
4FVD
  • Download 4fvd
  • View 4fvd
Molmil generated image of 4fvd
CRYSTAL STRUCTURE OF EV71 2A PROTEINASE C110A MUTANT IN COMPLEX WITH SUBSTRATE
Descriptor:2A proteinase, 10-mer peptide from 2A proteinase, ZINC ION
Authors:Cai, Q., Muhammad, Y., Liu, W., Gao, Z., Peng, X., Cai, Y., Wu, C., Zheng, Q., Li, J., Lin, T.
Deposit date:2012-06-29
Release date:2013-06-19
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Conformational Plasticity of 2A Proteinase from Enterovirus 71
J.Virol., 87, 2013
4GHQ
  • Download 4ghq
  • View 4ghq
Molmil generated image of 4ghq
CRYSTAL STRUCTURE OF EV71 3C PROTEINASE
Descriptor:3C proteinase
Authors:Chen, C., Wu, C., Cai, Q., Li, N., Peng, X., Cai, Y., Yin, K., Chen, X., Wang, X., Zhang, R., Liu, L., Chen, S., Li, J., Lin, T.
Deposit date:2012-08-08
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
4GHT
  • Download 4ght
  • View 4ght
Molmil generated image of 4ght
CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH AG7088
Descriptor:3C proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
Authors:Chen, C., Wu, C., Cai, Q., Li, N., Peng, X., Cai, Y., Yin, K., Chen, X., Wang, X., Zhang, R., Liu, L., Chen, S., Li, J., Lin, T.
Deposit date:2012-08-08
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
4JGV
  • Download 4jgv
  • View 4jgv
Molmil generated image of 4jgv
CRYSTAL STRUCTURE OF HUMAN NUR77 LIGAND-BINDING DOMAIN IN COMPLEX WITH THPN
Descriptor:Nuclear receptor subfamily 4 group A member 1, 1-(3,4,5-trihydroxyphenyl)nonan-1-one, GLYCEROL
Authors:Zhang, Q., Li, F., Li, A., Tian, X., Wan, W., Wan, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-03-04
Release date:2013-12-18
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.
Nat.Chem.Biol., 10, 2014
4KZI
  • Download 4kzi
  • View 4kzi
Molmil generated image of 4kzi
CRYSTAL STRUCTURE OF TR3 LBD IN COMPLEX WITH DPDO
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL, 1-(3,5-dimethoxyphenyl)decan-1-one
Authors:Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-05-30
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
4KZJ
  • Download 4kzj
  • View 4kzj
Molmil generated image of 4kzj
CRYSTAL STRUCTURE OF TR3 LBD L449W MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-05-30
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
4KZM
  • Download 4kzm
  • View 4kzm
Molmil generated image of 4kzm
CRYSTAL STRUCTURE OF TR3 LBD S553A MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-05-30
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
4R6M
  • Download 4r6m
  • View 4r6m
Molmil generated image of 4r6m
CRYSTAL STRUCTURE OF DNA DUPLEX CONTAINING TWO CONSECUTIVE MERCURY-MEDIATED BASE PAIRS
Descriptor:DNA (5'-D(P*GP*GP*AP*CP*TP*TP*CP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*GP*TP*TP*GP*TP*CP*C)-3'), MERCURY (II) ION
Authors:Xu, C.Y., Yu, F., Wang, L.H., Zhao, Y., Lin, T., Fan, C.H., He, J.H.
Deposit date:2014-08-26
Release date:2015-09-02
Method:X-RAY DIFFRACTION (2.357 Å)
Cite:Crystal Structure of DNA Duplex Containing Two Consecutive Mercury-mediated Base Pairs
To be Published
4RZF
  • Download 4rzf
  • View 4rzf
Molmil generated image of 4rzf
CRYSTAL STRUCTURE ANALYSIS OF THE NUR77 LIGAND BINDING DOMAIN, S441W MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
Deposit date:2014-12-21
Release date:2015-03-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
4RZG
  • Download 4rzg
  • View 4rzg
Molmil generated image of 4rzg
CRYSTAL STRUCTURE ANALYSIS OF THE DNPA-BOUNDED NUR77 LIGAND BINDING DOMAIN
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL, pentyl (3,5-dihydroxy-2-nonanoylphenyl)acetate
Authors:Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
Deposit date:2014-12-21
Release date:2015-03-18
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
5C1U
  • Download 5c1u
  • View 5c1u
Molmil generated image of 5c1u
CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND XB
Descriptor:3C proteinase, Nalpha-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-enoyl}-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C1X
  • Download 5c1x
  • View 5c1x
Molmil generated image of 5c1x
CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND VIII
Descriptor:3C proteinase, Nalpha-[(benzyloxy)carbonyl]-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C1Y
  • Download 5c1y
  • View 5c1y
Molmil generated image of 5c1y
CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 1
Descriptor:3C proteinase, N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-Nalpha-[(propan-2-yloxy)carbonyl]-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C20
  • Download 5c20
  • View 5c20
Molmil generated image of 5c20
CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 2
Descriptor:3C proteinase, Nalpha-[(2-methylpropoxy)carbonyl]-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5DP3
  • Download 5dp3
  • View 5dp3
Molmil generated image of 5dp3
CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 2
Descriptor:3C proteinase, ethyl (4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-[(3-phenylpropanoyl)amino]pent-2-enoate
Authors:Wu, C., Zhang, L., Li, P., Cai, Q., Peng, X., Li, N., Cai, Y., Li, J., Lin, T.
Deposit date:2015-09-12
Release date:2016-03-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
<123>