8GY0
 
 | | Agrocybe pediades linalool sunthase (Ap.LS) | | Descriptor: | Terpene synthase | | Authors: | Rehka, T, Sharma, D, Lin, F, Lim, C, Choong, Y.K, Chacko, J, Zhang, C. | | Deposit date: | 2022-09-21 | | Release date: | 2023-04-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.988 Å) | | Cite: | Structural Understanding of Fungal Terpene Synthases for the Formation of Linear or Cyclic Terpene Products.
Acs Catalysis, 13, 2023
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2XA8
 | | Crystal structure of the Fab domain of omalizumab at 2.41A | | Descriptor: | OMALIZUMAB HEAVY CHAIN, OMALIZUMAB LIGHT CHAIN | | Authors: | Huang, C.H, Hung, F.H.A, Lim, C, Chang, T.W, Ma, C. | | Deposit date: | 2010-03-30 | | Release date: | 2011-05-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Structural and Physical Basis for Anti-IgE Therapy.
Sci Rep, 5, 2015
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4LKX
 | | Humanized antibody 4B12 Fab complexed with a CemX segment | | Descriptor: | CemX segment, Fab fragment heavy chain, Fab fragment light chain | | Authors: | Chu, H.M, Wright, J, Chan, Y.H, Lin, C.J, Chang, T.W, Lim, C. | | Deposit date: | 2013-07-09 | | Release date: | 2014-01-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations.
Nat Commun, 5, 2014
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6X1H
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6X1G
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6W6W
 | | Cryo-EM structure of CST bound to telomeric single-stranded DNA | | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | | Authors: | Lim, C, Barbour, A.T, Zaug, A.J, Goodrich, K.J, McKay, A.E, Wuttke, D.S, Cech, T.R. | | Deposit date: | 2020-03-17 | | Release date: | 2020-06-03 | | Last modified: | 2020-06-17 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The structure of human CST reveals a decameric assembly bound to telomeric DNA.
Science, 368, 2020
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8D0B
 | | Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template | | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | | Authors: | He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. | | Deposit date: | 2022-05-26 | | Release date: | 2022-06-22 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | Structures of the human CST-Pol alpha-primase complex bound to telomere templates.
Nature, 608, 2022
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8D0K
 | | Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template - PRIM2C advanced PIC | | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | | Authors: | He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. | | Deposit date: | 2022-05-26 | | Release date: | 2022-06-22 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (4.27 Å) | | Cite: | Structures of the human CST-Pol alpha-primase complex bound to telomere templates.
Nature, 608, 2022
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8D96
 | | Human DNA polymerase alpha/primase elongation complex I bound to primer/template | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... | | Authors: | He, Q, Baranovskiy, A, Lim, C, Tahirov, T. | | Deposit date: | 2022-06-09 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structures of human primosome elongation complexes.
Nat.Struct.Mol.Biol., 30, 2023
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8D9D
 | | Human DNA polymerase-alpha/primase elongation complex II bound to primer/template | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... | | Authors: | He, Q, Baranovskiy, A, Lim, C, Tahirov, T. | | Deposit date: | 2022-06-09 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Structures of human primosome elongation complexes.
Nat.Struct.Mol.Biol., 30, 2023
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6PWY
 | | Structure of C. elegans ZK177.8, SAMHD1 ortholog | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Lim, C.S, Maehigashi, T, Wade, L.R, Bowen, N, Knecht, K, Xiong, Y, Kim, B. | | Deposit date: | 2019-07-24 | | Release date: | 2020-07-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | ZK177.8 of Caenorhabditis elegans:
Aicardi-Goutieres Syndrome SAMHD1 Ortholog
To Be Published
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5ZLQ
 | | Crystal Structure of C1orf123 | | Descriptor: | UPF0587 protein C1orf123, ZINC ION | | Authors: | Furukawa, Y, Lim, C.T, Tosha, T. | | Deposit date: | 2018-03-29 | | Release date: | 2018-10-10 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Identification of a novel zinc-binding protein, C1orf123, as an interactor with a heavy metal-associated domain
PLoS ONE, 13, 2018
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6UPU
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6UPS
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5XQH
 | | Crystal structure of truncated human Rogdi | | Descriptor: | Protein rogdi homolog | | Authors: | Lee, H, Lee, C. | | Deposit date: | 2017-06-07 | | Release date: | 2017-07-12 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | The crystal structure of human Rogdi provides insight into the causes of Kohlschutter-Tonz Syndrome
Sci Rep, 7, 2017
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5XQI
 | | Crystal structure of full-length human Rogdi | | Descriptor: | Protein rogdi homolog | | Authors: | Lee, H, Lee, C. | | Deposit date: | 2017-06-07 | | Release date: | 2017-07-12 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of human Rogdi provides insight into the causes of Kohlschutter-Tonz Syndrome
Sci Rep, 7, 2017
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7FAD
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7SV4
 | | Crystal structure of SpaA-SLH in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAc-(1->3)-4,6-Pyr-beta-D-ManNAcOMe | | Descriptor: | GLYCEROL, Surface (S-) layer glycoprotein, methyl 2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl-(1->4)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)-2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranoside | | Authors: | Legg, M.S.G, Evans, S.V. | | Deposit date: | 2021-11-18 | | Release date: | 2022-03-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue.
J.Biol.Chem., 298, 2022
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7SV6
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7SV3
 | | Crystal structure of SpaA-SLH in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAcOMe | | Descriptor: | Surface (S-) layer glycoprotein, methyl 2-acetamido-4-O-{2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranoside | | Authors: | Legg, M.S.G, Evans, S.V. | | Deposit date: | 2021-11-18 | | Release date: | 2022-03-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue.
J.Biol.Chem., 298, 2022
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7SV5
 | | Crystal structure of SpaA-SLH/G109A in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAcOMe | | Descriptor: | GLYCEROL, Surface (S-) layer glycoprotein, methyl 2-acetamido-4-O-{2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranoside | | Authors: | Legg, M.S.G, Evans, S.V. | | Deposit date: | 2021-11-18 | | Release date: | 2022-03-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue.
J.Biol.Chem., 298, 2022
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4Y00
 | | Crystal Structure of Human TDP-43 RRM1 Domain with D169G Mutation in Complex with an Unmodified Single-stranded DNA | | Descriptor: | DNA (5'-D(P*TP*TP*GP*AP*GP*CP*GP*T)-3'), TAR DNA-binding protein 43 | | Authors: | Chiang, C.H, Kuo, P.H, Yang, W.Z, Yuan, H.S. | | Deposit date: | 2015-02-05 | | Release date: | 2016-02-10 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
Sci Rep, 6, 2016
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4Y0F
 | | Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA | | Descriptor: | DNA (5'-D(*GP*TP*TP*GP*AP*GP*CP*GP*TP*T)-3'), TAR DNA-binding protein 43 | | Authors: | Chiang, C.H, Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yuan, H.S. | | Deposit date: | 2015-02-06 | | Release date: | 2016-02-10 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.648 Å) | | Cite: | Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
Sci Rep, 6, 2016
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7DA6
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5E7S
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