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5JVD
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TUBULIN-TUB092 COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Canela, M.-D., Noppen, S., Bueno, O., Prota, A.E., Bargsten, K., Saez-Calvo, G., Jimeno, M.-L., Benkheil, M., Ribatti, D., Velazquez, S., Camarasa, M.-J., Diaz, J.F., Steinmetz, M.O., Priego, E.-M., Perez-Perez, M.-J., Liekens, S.
登録日2016-05-11
公開日2016-06-08
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Antivascular and antitumor properties of the tubulin-binding chalcone TUB091.
Oncotarget, 8, 2017
2J0F
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STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN
分子名称:THYMIDINE PHOSPHORYLASE, THYMINE
著者El Omari, K., Bronckaers, A., Liekens, S., Perez-Perez, M.J., Balzarini, J., Stammers, D.K.
登録日2006-08-02
公開日2006-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural Basis for Non-Competitive Product Inhibition in Human Thymidine Phosphorylase: Implications for Drug Design.
Biochem.J., 399, 2006
5OUG
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HUMANIZED ALPHA-ACHBP (ACETYLCHOLINE BINDING PROTEIN) IN COMPLEX WITH LOBELINE AND ALLOSTERIC BINDER FRAGMENT 4.
分子名称:Humanized alpha-AChBP, Alpha-Lobeline, N-ACETYL-D-GLUCOSAMINE, ...
著者Delbart, F., Gruss, F., Ulens, C.
登録日2017-08-23
公開日2017-12-20
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献An allosteric binding site of the alpha 7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.
J. Biol. Chem., 293, 2018
5OUH
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HUMANIZED ALPHA-ACHBP (ACETYLCHOLINE BINDING PROTEIN) IN COMPLEX WITH LOBELINE.
分子名称:Acetylcholine binding protein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Delbart, F., Gruss, F., Ulens, C.
登録日2017-08-23
公開日2017-11-29
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An allosteric binding site of the alpha 7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.
J. Biol. Chem., 293, 2018
5OUI
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HUMANIZED ALPHA-ACHBP (ACETYLCHOLINE BINDING PROTEIN) IN COMPLEX WITH ALLOSTERIC BINDER FRAGMENT CU2017
分子名称:Acetylcholine binding protein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Delbart, F., Gruss, F., Ulens, C.
登録日2017-08-23
公開日2017-11-29
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献An allosteric binding site of the alpha 7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.
J. Biol. Chem., 293, 2018
4R5P
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) WITH DNA AND A NUCLEOSIDE TRIPHOSPHATE MIMIC ALPHA-CARBOXY NUCLEOSIDE PHOSPHONATE INHIBITOR
分子名称:HIV-1 reverse transcriptase, p66 subunit, p51 subunit, ...
著者Das, K., Martinez, S.E., Arnold, E.
登録日2014-08-21
公開日2015-03-11
最終更新日2015-04-01
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics.
Proc.Natl.Acad.Sci.USA, 112, 2015
6FKJ
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TUBULIN-TUB075 COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Prota, A.E., Steinmetz, M.O., Priego, E.-M.
登録日2018-01-24
公開日2018-03-21
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.
Sci Rep, 8, 2018
6FKL
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TUBULIN-TUB015 COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Prota, A.E., Steinmetz, M.O., Priego, E.-M.
登録日2018-01-24
公開日2018-03-21
実験手法X-RAY DIFFRACTION (2.098 Å)
主引用文献High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.
Sci Rep, 8, 2018