Author results

4RKW
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CRYSTAL STRUCTURE OF DJ-1
Descriptor:Protein DJ-1
Authors:Liddington, R.C.
Deposit date:2014-10-14
Release date:2015-08-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models.
J.Neurosci., 34, 2014
4RKY
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CRYSTAL STRUCTURE OF DJ-1 ISOFORM X1
Descriptor:Protein DJ-1
Authors:Liddington, R.C.
Deposit date:2014-10-14
Release date:2015-08-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models.
J.Neurosci., 34, 2014
1A37
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14-3-3 PROTEIN ZETA BOUND TO PS-RAF259 PEPTIDE
Descriptor:14-3-3 PROTEIN ZETA, PS-RAF259 PEPTIDE LSQRQRST(SEP)TPNVHM
Authors:Petosa, C., Masters, S.C., Pohl, J., Wang, B., Fu, H., Liddington, R.C.
Deposit date:1998-01-28
Release date:1999-03-02
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove.
J.Biol.Chem., 273, 1998
1A38
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14-3-3 PROTEIN ZETA BOUND TO R18 PEPTIDE
Descriptor:14-3-3 PROTEIN ZETA, R18 PEPTIDE (PHCVPRDLSWLDLEANMCLP)
Authors:Petosa, C., Masters, S.C., Pohl, J., Wang, B., Fu, H., Liddington, R.C.
Deposit date:1998-01-28
Release date:1999-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove.
J.Biol.Chem., 273, 1998
1IJK
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THE VON WILLEBRAND FACTOR MUTANT (I546V) A1 DOMAIN-BOTROCETIN COMPLEX
Descriptor:von Willebrand factor, Botrocetin
Authors:Fukuda, K., Doggett, T.A., Bankston, L.A., Cruz, M.A., Diacovo, T.G., Liddington, R.C.
Deposit date:2001-04-26
Release date:2002-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of von Willebrand factor activation by the snake toxin botrocetin.
Structure, 10, 2002
1AB4
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59KDA FRAGMENT OF GYRASE A FROM E. COLI
Descriptor:GYRASE A
Authors:Cabral, J.H.M., Maxwell, A., Liddington, R.C.
Deposit date:1997-02-03
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the breakage-reunion domain of DNA gyrase.
Nature, 388, 1997
1ACC
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ANTHRAX PROTECTIVE ANTIGEN
Descriptor:ANTHRAX PROTECTIVE ANTIGEN, CALCIUM ION
Authors:Petosa, C., Liddington, R.C.
Deposit date:1997-02-05
Release date:1998-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the anthrax toxin protective antigen.
Nature, 385, 1997
1AOX
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I DOMAIN FROM INTEGRIN ALPHA2-BETA1
Descriptor:INTEGRIN ALPHA 2 BETA, MAGNESIUM ION
Authors:Emsley, J., King, S.L., Bergelson, J.M., Liddington, R.C.
Deposit date:1997-07-13
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the I domain from integrin alpha2beta1.
J.Biol.Chem., 272, 1997
1F0C
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STRUCTURE OF THE VIRAL SERPIN CRMA
Descriptor:ICE INHIBITOR, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:Renatus, M., Zhou, Q., Stennicke, H.R., Snipas, S.J., Turk, D., Bankston, L.A., Liddington, R.C., Salvesen, G.S.
Deposit date:2000-05-15
Release date:2000-09-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structure of the apoptotic suppressor CrmA in its cleaved form.
Structure Fold.Des., 8, 2000
1I3O
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CRYSTAL STRUCTURE OF THE COMPLEX OF XIAP-BIR2 AND CASPASE 3
Descriptor:CASPASE 3, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, ZINC ION
Authors:Riedl, S.J., Renatus, M., Schwarzenbacher, R., Zhou, Q., Sun, C., Fesik, S.W., Liddington, R.C., Salvesen, G.S.
Deposit date:2001-02-15
Release date:2001-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the inhibition of caspase-3 by XIAP.
Cell(Cambridge,Mass.), 104, 2001
1IJB
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THE VON WILLEBRAND FACTOR MUTANT (I546V) A1 DOMAIN
Descriptor:von Willebrand factor
Authors:Fukuda, K., Doggett, T.A., Bankston, L.A., Cruz, M.A., Diacovo, T.G., Liddington, R.C.
Deposit date:2001-04-25
Release date:2002-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of von Willebrand factor activation by the snake toxin botrocetin.
Structure, 10, 2002
1J7N
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ANTHRAX TOXIN LETHAL FACTOR
Descriptor:Lethal Factor precursor, SULFATE ION, ZINC ION
Authors:Pannifer, A.D., Wong, T.Y., Schwarzenbacher, R., Renatus, M., Petosa, C., Collier, R.J., Bienkowska, J., Lacy, D.B., Park, S., Leppla, S.H., Hanna, P., Liddington, R.C.
Deposit date:2001-05-17
Release date:2001-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1JKY
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CRYSTAL STRUCTURE OF THE ANTHRAX LETHAL FACTOR (LF): WILD-TYPE LF COMPLEXED WITH THE N-TERMINAL SEQUENCE OF MAPKK2
Descriptor:Lethal Factor, mitogen-activated protein kinase kinase 2
Authors:Pannifer, A.D., Wong, T.Y., Schwarzenbacher, R., Renatus, M., Petosa, C., Collier, R.J., Bienkowska, J., Lacy, D.B., Park, S., Leppla, S.H., Hanna, P., Liddington, R.C.
Deposit date:2001-07-13
Release date:2001-11-07
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1JXQ
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STRUCTURE OF CLEAVED, CARD DOMAIN DELETED CASPASE-9
Descriptor:Caspase-9, benzoxycarbonyl-Val-Ala-Asp-fluoromethyl ketone Inhibitor
Authors:Renatus, M., Stennicke, H.R., Scott, F.L., Liddington, R.C., Salvesen, G.S.
Deposit date:2001-09-08
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dimer formation drives the activation of the cell death protease caspase 9.
Proc.Natl.Acad.Sci.USA, 98, 2001
1K40
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CRYSTAL STRUCTURE OF THE FAT DOMAIN OF FOCAL ADHESION KINASE
Descriptor:adhesion kinase
Authors:Hayashi, I., Vuori, K., Liddington, R.C.
Deposit date:2001-10-04
Release date:2002-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin
Nat.Struct.Biol., 9, 2002
1MF7
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INTEGRIN ALPHA M I DOMAIN
Descriptor:INTEGRIN ALPHA M
Authors:McCleverty, C.J., Liddington, R.C.
Deposit date:2002-08-09
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
1MIX
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CRYSTAL STRUCTURE OF A FERM DOMAIN OF TALIN
Descriptor:Talin
Authors:Garcia-Alvarez, B., de Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MIZ
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor:integrin beta3, TALIN
Authors:Garcia-Alvarez, B., de Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MK7
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor:Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B., De Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MK9
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor:Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B., De Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1N9Z
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INTEGRIN ALPHA M I DOMAIN MUTANT
Descriptor:Integrin alpha-M, MAGNESIUM ION
Authors:McCleverty, C.J., Liddington, R.C.
Deposit date:2002-11-26
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
1NA5
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INTEGRIN ALPHA M I DOMAIN
Descriptor:Integrin alpha-M
Authors:McCleverty, C.J., Liddington, R.C.
Deposit date:2002-11-26
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
1OTW
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CRYSTAL STRUCTURE OF PQQC IN COMPLEX WITH PQQ AND A PUTATIVE H2O2
Descriptor:Coenzyme PQQ synthesis protein C, PYRROLOQUINOLINE QUINONE, HYDROGEN PEROXIDE
Authors:Magnusson, O.T., Toyama, H., Saeki, M., Rojas, A., Reed, J.C., Liddington, R.C., Klinman, J.P., Schwarzenbacher, R.
Deposit date:2003-03-23
Release date:2004-05-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
1PWP
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CRYSTAL STRUCTURE OF THE ANTHRAX LETHAL FACTOR COMPLEXED WITH SMALL MOLECULE INHIBITOR NSC 12155
Descriptor:Lethal factor, ZINC ION, N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA
Authors:Wong, T.Y., Schwarzenbacher, R., Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification of small molecule inhibitors of anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1PWQ
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CRYSTAL STRUCTURE OF ANTHRAX LETHAL FACTOR COMPLEXED WITH THIOACETYL-TYR-PRO-MET-AMIDE, A METAL-CHELATING PEPTIDYL SMALL MOLECULE INHIBITOR
Descriptor:Lethal factor, ZINC ION, N-(SULFANYLACETYL)TYROSYLPROLYLMETHIONINAMIDE
Authors:Wong, T.Y., Schwarzenbacher, R., Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004