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4RZK
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BU of 4rzk by Molmil
Crystal structure of Sulfolobus solfataricus Hsp20.1 ACD
Descriptor: Small heat shock protein hsp20 family
Authors:Liang, L, Yun, C.H.
Deposit date:2014-12-22
Release date:2015-12-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.677 Å)
Cite:Crystal structure and function of an unusual dimeric Hsp20.1 provide insight into the thermal protection mechanism of small heat shock proteins.
Biochem.Biophys.Res.Commun., 2015
6JOI
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BU of 6joi by Molmil
Crystal structure of PDGFRA T674I in complex with crenolanib by co-crystallization
Descriptor: 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, Platelet-derived growth factor receptor alpha
Authors:Liang, L, Yan, X.E, Yun, C.H.
Deposit date:2019-03-22
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of PDGFRA T674I in complex with crenolanib by co-crystallization
To Be Published
6JOK
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BU of 6jok by Molmil
Crystal structure of PDGFRA in complex with sunitinib by soaking
Descriptor: CHLORIDE ION, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, Platelet-derived growth factor receptor alpha
Authors:Liang, L, Yan, X.E, Yun, C.H.
Deposit date:2019-03-22
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of PDGFRA in complex with sunitinib by soaking
To Be Published
6JOL
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BU of 6jol by Molmil
Crystal structure of PDGFRA in complex with imatinib by co-crystallization
Descriptor: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Platelet-derived growth factor receptor alpha
Authors:Liang, L, Yan, X.E, Yun, C.H.
Deposit date:2019-03-22
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of PDGFRA in complex with imatinib by co-crystallization
To Be Published
6JOJ
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BU of 6joj by Molmil
Crystal structure of PDGFRA T674I in complex with crenolanib by soaking
Descriptor: 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, CHLORIDE ION, Platelet-derived growth factor receptor alpha, ...
Authors:Liang, L, Yan, X.E, Yun, C.H.
Deposit date:2019-03-22
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of PDGFRA in complex with crenolanib by soaking
To Be Published
3F7O
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BU of 3f7o by Molmil
Crystal structure of Cuticle-Degrading Protease from Paecilomyces lilacinus (PL646)
Descriptor: (MSU)(ALA)(ALA)(PRO)(VAL), CALCIUM ION, Serine protease
Authors:Liang, L, Lou, Z, Meng, Z, Rao, Z, Zhang, K.
Deposit date:2008-11-10
Release date:2009-11-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
Faseb J., 24, 2010
3F7M
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BU of 3f7m by Molmil
Crystal structure of apo Cuticle-Degrading Protease (ver112) from Verticillium psalliotae
Descriptor: Alkaline serine protease ver112
Authors:Liang, L, Lou, Z, Ye, F, Meng, Z, Rao, Z, Zhang, K.
Deposit date:2008-11-09
Release date:2009-11-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
Faseb J., 24, 2010
6KTO
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BU of 6kto by Molmil
Crystal structure of human SHLD3-C-REV7-O-REV7-SHLD2 complex
Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2, Shieldin complex subunit 3
Authors:Liang, L, Yin, Y.
Deposit date:2019-08-28
Release date:2020-04-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.4497633 Å)
Cite:Molecular basis for assembly of the shieldin complex and its implications for NHEJ.
Nat Commun, 11, 2020
5XDP
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BU of 5xdp by Molmil
K11/48-branched teraubiquitin
Descriptor: D-ubiquitin, ubiquitin-B
Authors:Liang, L, Gao, S, Tang, S.
Deposit date:2017-03-28
Release date:2017-04-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.376 Å)
Cite:K11/48-branched teraubiquitin
To Be Published
4R94
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BU of 4r94 by Molmil
Structure of the nickase domain of NS1 from MVM complexed with magnesium
Descriptor: MAGNESIUM ION, Non-structural protein NS1
Authors:Liang, L, Zhao, H, Tang, L.
Deposit date:2014-09-03
Release date:2015-01-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.668 Å)
Cite:Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.
Virology, 476C, 2014
5VGT
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BU of 5vgt by Molmil
X-ray structure of bacteriophage Sf6 tail adaptor protein gp7
Descriptor: CALCIUM ION, Gene 7 protein, MAGNESIUM ION
Authors:Tang, L, Liang, L, Zhao, H.
Deposit date:2017-04-11
Release date:2017-12-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.776 Å)
Cite:High-resolution structure of podovirus tail adaptor suggests repositioning of an octad motif that mediates the sequential tail assembly.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5GWN
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BU of 5gwn by Molmil
Crystal structure of human RCC2
Descriptor: Protein RCC2, SULFATE ION
Authors:Liang, L, Yun, C.H, Yin, Y.X.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.309 Å)
Cite:RCC2 is a novel p53 target in suppressing metastasis.
Oncogene, 37, 2018
5K5X
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BU of 5k5x by Molmil
Crystal structure of human PDGFRA
Descriptor: Platelet-derived growth factor receptor alpha, SULFATE ION
Authors:Yan, X.E, Liang, L, Yun, C.H.
Deposit date:2016-05-24
Release date:2016-08-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.168 Å)
Cite:Structural and biochemical studies of the PDGFRA kinase domain
Biochem.Biophys.Res.Commun., 477, 2016
7MEY
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BU of 7mey by Molmil
Structure of yeast Ubr1 in complex with Ubc2 and monoubiquitinated N-degron
Descriptor: 2-(ethylamino)ethane-1-thiol, E3 ubiquitin-protein ligase UBR1, Monoubiquitinated N-degron, ...
Authors:Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M.
Deposit date:2021-04-08
Release date:2021-11-24
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural insights into Ubr1-mediated N-degron polyubiquitination.
Nature, 600, 2021
7MEX
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BU of 7mex by Molmil
Structure of yeast Ubr1 in complex with Ubc2 and N-degron
Descriptor: E3 ubiquitin-protein ligase UBR1, N-degron, Ubiquitin, ...
Authors:Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M.
Deposit date:2021-04-08
Release date:2021-11-24
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural insights into Ubr1-mediated N-degron polyubiquitination.
Nature, 600, 2021
2MI7
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BU of 2mi7 by Molmil
Solution NMR structure of alpha3Y
Descriptor: de novo protein a3Y
Authors:Glover, S.D, Jorge, C, Liang, L, Valentine, K.G, Hammarstrom, L, Tommos, C.
Deposit date:2013-12-10
Release date:2014-08-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Photochemical tyrosine oxidation in the structurally well-defined alpha 3Y protein: proton-coupled electron transfer and a long-lived tyrosine radical.
J.Am.Chem.Soc., 136, 2014
6JBM
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BU of 6jbm by Molmil
Crystal structure of the TRIM14 PRYSPRY domain
Descriptor: SULFATE ION, Tripartite motif-containing protein 14
Authors:Yin, Y.X, Yu, Y, Liang, L.
Deposit date:2019-01-26
Release date:2020-03-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The TRIM14 PRYSPRY domain mediates protein interaction via its basic interface.
Febs Lett., 593, 2019
2LXY
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BU of 2lxy by Molmil
NMR structure of 2-MERCAPTOPHENOL-ALPHA3C
Descriptor: 2-MERCAPTOPHENOL, 2-mercaptophenol-alpha3C
Authors:Tommos, C, Valentine, K.G, Martinez-Rivera, M.C, Liang, L, Moorman, V.R.
Deposit date:2012-09-06
Release date:2013-02-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Reversible phenol oxidation and reduction in the structurally well-defined 2-Mercaptophenol-alpha(3)C protein.
Biochemistry, 52, 2013
8JE1
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BU of 8je1 by Molmil
An asymmetry dimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complexed with BEX2
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ...
Authors:Dai, Z, Liang, L, Yin, Y.X.
Deposit date:2023-05-15
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 2024
8JE2
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BU of 8je2 by Molmil
Cryo-EM structure of neddylated Cul2-Rbx1-EloBC-FEM1B complexed with FNIP1-FLCN
Descriptor: Cullin-2, Elongin-B, Elongin-C, ...
Authors:Dai, Z, Liang, L, Yin, Y.X.
Deposit date:2023-05-15
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 2024
8IJ1
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BU of 8ij1 by Molmil
Protomer 1 and 2 of the asymmetry trimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complex
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ...
Authors:Dai, Z, Liang, L, Yin, Y.X.
Deposit date:2023-02-24
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 2024
6A32
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BU of 6a32 by Molmil
Crystal structure of PDGFRA kinase domain mutant T674I
Descriptor: Platelet-derived growth factor receptor alpha
Authors:Yan, X.E, Liang, L, Yun, C.H.
Deposit date:2018-06-14
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structure of PDGFRA kinase domain mutant T674I
To Be Published
4WUM
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BU of 4wum by Molmil
X-ray crystal structure of Chalcone Synthase from Freesia hybrida
Descriptor: Chalcone synthase
Authors:Almqvist, J, Jiang, W.S, Wang, L, Huang, Y.
Deposit date:2014-11-02
Release date:2014-11-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Molecular and Biochemical Analysis of Chalcone Synthase from Freesia hybrid in Flavonoid Biosynthetic Pathway.
Plos One, 10, 2015
8WGW
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BU of 8wgw by Molmil
Local refinement of RBD-ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Wei, X, Zhang, Z.
Deposit date:2023-09-22
Release date:2024-02-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.
Nat.Immunol., 2024
8WGV
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BU of 8wgv by Molmil
BA.2(S375) Spike (S6P)/hACE2 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Wei, X, Zhang, Z.
Deposit date:2023-09-22
Release date:2024-02-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.
Nat.Immunol., 2024

 

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