Author results

3F7M
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CRYSTAL STRUCTURE OF APO CUTICLE-DEGRADING PROTEASE (VER112) FROM VERTICILLIUM PSALLIOTAE
Descriptor:Alkaline serine protease ver112
Authors:Liang, L., Lou, Z., Ye, F., Meng, Z., Rao, Z., Zhang, K.
Deposit date:2008-11-09
Release date:2009-11-17
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
Faseb J., 24, 2010
3F7O
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CRYSTAL STRUCTURE OF CUTICLE-DEGRADING PROTEASE FROM PAECILOMYCES LILACINUS (PL646)
Descriptor:Serine protease, (ALA)(ALA)(PRO)(VAL), (4S)-4-hydroxy-4-methoxybutanoic acid, ...
Authors:Liang, L., Lou, Z., Meng, Z., Rao, Z., Zhang, K.
Deposit date:2008-11-10
Release date:2009-11-17
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
Faseb J., 24, 2010
4RZK
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CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS HSP20.1 ACD
Descriptor:Small heat shock protein hsp20 family
Authors:Liang, L., Yun, C.H.
Deposit date:2014-12-22
Release date:2015-12-23
Method:X-RAY DIFFRACTION (2.677 Å)
Cite:Crystal structure and function of an unusual dimeric Hsp20.1 provide insight into the thermal protection mechanism of small heat shock proteins.
Biochem.Biophys.Res.Commun., 2015
5XDP
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K11/48-BRANCHED TERAUBIQUITIN
Descriptor:D-ubiquitin, ubiquitin-B
Authors:Liang, L., Gao, S., Tang, S.
Deposit date:2017-03-28
Release date:2017-04-19
Method:X-RAY DIFFRACTION (2.376 Å)
Cite:K11/48-branched teraubiquitin
To Be Published
4R94
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STRUCTURE OF THE NICKASE DOMAIN OF NS1 FROM MVM COMPLEXED WITH MAGNESIUM
Descriptor:Non-structural protein NS1, MAGNESIUM ION
Authors:Liang, L., Zhao, H., Tang, L.
Deposit date:2014-09-03
Release date:2015-01-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.668 Å)
Cite:Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.
Virology, 476C, 2014
5VGT
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X-RAY STRUCTURE OF BACTERIOPHAGE SF6 TAIL ADAPTOR PROTEIN GP7
Descriptor:Gene 7 protein, CALCIUM ION, MAGNESIUM ION
Authors:Tang, L., Liang, L., Zhao, H.
Deposit date:2017-04-11
Release date:2017-12-27
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.776 Å)
Cite:High-resolution structure of podovirus tail adaptor suggests repositioning of an octad motif that mediates the sequential tail assembly.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5GWN
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CRYSTAL STRUCTURE OF HUMAN RCC2
Descriptor:Protein RCC2, SULFATE ION
Authors:Liang, L., Yun, C.H., Yin, Y.X.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.309 Å)
Cite:RCC2 is a novel p53 target in suppressing metastasis.
Oncogene, 37, 2018
5K5X
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CRYSTAL STRUCTURE OF HUMAN PDGFRA
Descriptor:Platelet-derived growth factor receptor alpha, SULFATE ION
Authors:Yan, X.E., Liang, L., Yun, C.H.
Deposit date:2016-05-24
Release date:2016-08-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.168 Å)
Cite:Structural and biochemical studies of the PDGFRA kinase domain
Biochem.Biophys.Res.Commun., 477, 2016
2MI7
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SOLUTION NMR STRUCTURE OF ALPHA3Y
Descriptor:de novo protein a3Y
Authors:Glover, S.D., Jorge, C., Liang, L., Valentine, K.G., Hammarstrom, L., Tommos, C.
Deposit date:2013-12-10
Release date:2014-08-20
Last modified:2015-01-14
Method:SOLUTION NMR
Cite:Photochemical tyrosine oxidation in the structurally well-defined alpha 3Y protein: proton-coupled electron transfer and a long-lived tyrosine radical.
J.Am.Chem.Soc., 136, 2014
2LXY
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NMR STRUCTURE OF 2-MERCAPTOPHENOL-ALPHA3C
Descriptor:2-mercaptophenol-alpha3C, 2-MERCAPTOPHENOL
Authors:Tommos, C., Valentine, K.G., Martinez-Rivera, M.C., Liang, L., Moorman, V.R.
Deposit date:2012-09-06
Release date:2013-02-27
Last modified:2013-06-19
Method:SOLUTION NMR
Cite:Reversible phenol oxidation and reduction in the structurally well-defined 2-Mercaptophenol-alpha(3)C protein.
Biochemistry, 52, 2013
3MYG
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AURORA A KINASE COMPLEXED WITH SCH 1473759
Descriptor:Serine/threonine-protein kinase 6, TETRAETHYLENE GLYCOL, 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol
Authors:Hruza, A., Prosis, W., Ramanathan, L.
Deposit date:2010-05-10
Release date:2010-07-21
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core.
ACS Med Chem Lett, 1, 2010
3WRN
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MINUTE VIRUS OF MICE NON-STRUCTURAL PROTEIN-1N-TERMINAL NUCLEASE DOMAIN REVEALS A UNIQUE ZN2+ COORDINATION IN THE ACTIVE SITE POCKET AND SHOWS A NOVEL MODE OF DNA RECOGNITION AT THE ORIGIN OF REPLICATION
Descriptor:Non-capsid protein NS-1, SODIUM ION, ZINC ION
Authors:Tewary, S.K., Zhao, H., Tang, L.
Deposit date:2014-02-27
Release date:2015-01-21
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.
Virology, 476C, 2014
3WRO
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MINUTE VIRUS OF MICE NON-STRUCTURAL PROTEIN-1N-TERMINAL NUCLEASE DOMAIN REVEALS A UNIQUE ZN2+ COORDINATION IN THE ACTIVE SITE POCKET AND SHOWS A NOVEL MODE OF DNA RECOGNITION AT THE ORIGIN OF REPLICATION
Descriptor:Non-capsid protein NS-1, MANGANESE (II) ION
Authors:Tewary, S.K., Zhao, H., Tang, L.
Deposit date:2014-02-27
Release date:2015-01-21
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.
Virology, 476C, 2014
3WRQ
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MINUTE VIRUS OF MICE NON-STRUCTURAL PROTEIN-1N-TERMINAL NUCLEASE DOMAIN REVEALS A UNIQUE ZN2+ COORDINATION IN THE ACTIVE SITE POCKET AND SHOWS A NOVEL MODE OF DNA RECOGNITION AT THE ORIGIN OF REPLICATION
Descriptor:Non-capsid protein NS-1, NICKEL (II) ION
Authors:Tewary, S.K., Zhao, H., Tang, L.
Deposit date:2014-02-27
Release date:2015-01-21
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.
Virology, 476C, 2014
3WRR
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MINUTE VIRUS OF MICE NON-STRUCTURAL PROTEIN-1N-TERMINAL NUCLEASE DOMAIN REVEALS A UNIQUE ZN2+ COORDINATION IN THE ACTIVE SITE POCKET AND SHOWS A NOVEL MODE OF DNA RECOGNITION AT THE ORIGIN OF REPLICATION
Descriptor:Non-capsid protein NS-1, COPPER (II) ION
Authors:Tewary, S.K., Zhao, H., Tang, L.
Deposit date:2014-02-27
Release date:2015-01-21
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.
Virology, 476C, 2014
3WRS
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MINUTE VIRUS OF MICE NON-STRUCTURAL PROTEIN-1N-TERMINAL NUCLEASE DOMAIN REVEALS A UNIQUE ZN2+ COORDINATION IN THE ACTIVE SITE POCKET AND SHOWS A NOVEL MODE OF DNA RECOGNITION AT THE ORIGIN OF REPLICATION
Descriptor:Non-capsid protein NS-1, COBALT (II) ION
Authors:Tewary, S.K., Zhao, H., Tang, L.
Deposit date:2014-02-27
Release date:2015-01-21
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.
Virology, 476C, 2014
4DXD
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STAPHYLOCOCCAL AUREUS FTSZ IN COMPLEX WITH 723
Descriptor:Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, 3-[(6-chloro[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide
Authors:Lu, J., Soisson, S.M.
Deposit date:2012-02-27
Release date:2012-05-23
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics.
Sci Transl Med, 4, 2012
4PP4
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MINUTE VIRUS OF MICE NON-STRUCTURAL PROTEIN-1N-TERMINAL NUCLEASE DOMAIN REVEALS A UNIQUE ZN2+ COORDINATION IN THE ACTIVE SITE POCKET AND SHOWS A NOVEL MODE OF DNA RECOGNITION AT THE ORIGIN OF REPLICATION
Descriptor:Non-capsid protein NS-1, BETA-MERCAPTOETHANOL, SODIUM ION
Authors:Tewary, S.K., Zhao, H., Tang, L.
Deposit date:2014-02-26
Release date:2015-01-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding.
Virology, 476C, 2014
4WUM
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X-RAY CRYSTAL STRUCTURE OF CHALCONE SYNTHASE FROM FREESIA HYBRIDA
Descriptor:Chalcone synthase
Authors:Almqvist, J., Jiang, W.S., Wang, L., Huang, Y.
Deposit date:2014-11-02
Release date:2014-11-12
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Molecular and Biochemical Analysis of Chalcone Synthase from Freesia hybrid in Flavonoid Biosynthetic Pathway.
Plos One, 10, 2015
6ISU
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CRYSTAL STRUCTURE OF LYS27-LINKED DI-UBIQUITIN IN COMPLEX WITH ITS SELECTIVE INTERACTING PROTEIN UCHL3
Descriptor:Ubiquitin carboxyl-terminal hydrolase isozyme L3, Ubiquitin
Authors:Ding, S., Pan, M., Zheng, Q., Ren, Y., Hong, D.
Deposit date:2018-11-19
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.866 Å)
Cite:Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains.
Angew. Chem. Int. Ed. Engl., 58, 2019
5C5P
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CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR
Descriptor:Tankyrase-2, ZINC ION, (3R)-3-(1-hydroxy-2-methylpropan-2-yl)-1,3,4,5-tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one, ...
Authors:Lukacs, C.M., Janson, C.A.
Deposit date:2015-06-21
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
Acs Med.Chem.Lett., 6, 2015
5C5Q
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CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR
Descriptor:Tankyrase-2, ZINC ION, (3R)-10-methyl-3-(propan-2-yl)-1,3,4,5-tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one, ...
Authors:Lukacs, C.M., Janson, C.A.
Deposit date:2015-06-21
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
Acs Med.Chem.Lett., 6, 2015
5C5R
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CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR
Descriptor:Tankyrase-2, ZINC ION, (7R)-2-hydroxy-7-(propan-2-yl)-7,8-dihydro-5H-pyrano[4,3-b]pyridine-3-carbonitrile, ...
Authors:Lukacs, C.M., Janson, C.A.
Deposit date:2015-06-21
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
Acs Med.Chem.Lett., 6, 2015
2RHI
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CRYSTAL STRUCTURE OF THE 3-MBT DOMAIN FROM HUMAN L3MBTL1 IN COMPLEX WITH H1.5K27ME2 AT 1.66 ANGSTROM
Descriptor:Lethal(3)malignant brain tumor-like protein, Histone H1.5, TETRAETHYLENE GLYCOL, ...
Authors:Li, H., Patel, D.J.
Deposit date:2007-10-09
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2RHU
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CRYSTAL STRUCTURE OF THE 3-MBT REPEATS FROM HUMAN L3MBTL1 BOUND TO DIMETHYL-LYSINE AND IN CHIMERA WITH HISTONE H3.3(28-34)
Descriptor:Lethal(3)malignant brain tumor-like protein, SULFATE ION, N-DIMETHYL-LYSINE, ...
Authors:Li, H., Patel, D.J.
Deposit date:2007-10-09
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
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