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6IGC
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CRYSTAL STRUCTURE OF HPV58/33/52 CHIMERIC L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGD
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CRYSTAL STRUCTURE OF HPV58/33 CHIMERIC L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGE
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CRYSTAL STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 33 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-12-05
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
6IGF
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CRYSTAL STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 52 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Song, S., He, M.Z., Gu, Y., Li, S.W.
Deposit date:2018-09-25
Release date:2018-11-28
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
5J6R
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CRYSTAL STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 59 L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Yan, X.D., Yu, H., Gu, Y., Li, S.W.
Deposit date:2016-04-05
Release date:2016-05-18
Last modified:2016-07-06
Method:X-RAY DIFFRACTION (4.011 Å)
Cite:The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction.
Structure, 24, 2016
5JB1
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PSEUDO-ATOMIC STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 59 L1 VIRUS-LIKE PARTICLE
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Yan, X.D., Yu, H., Zheng, Q.B., Gu, Y., Li, S.W.
Deposit date:2016-04-13
Release date:2016-05-18
Last modified:2017-10-18
Method:ELECTRON MICROSCOPY (6 Å)
Cite:The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction.
Structure, 24, 2016
5X3P
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CRYSTAL STRUCTURE OF THE UBX DOMAIN OF HUMAN UBXD7
Descriptor:UBX domain-containing protein 7
Authors:Jiang, T., Li, Z., Wang, Y., Xu, M.
Deposit date:2017-02-06
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase
Biochem. Biophys. Res. Commun., 486, 2017
5X4L
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CRYSTAL STRUCTURE OF THE UBX DOMAIN OF HUMAN UBXD7 IN COMPLEX WITH P97 N DOMAIN
Descriptor:Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 7
Authors:Jiang, T., Li, Z., Wang, Y., Xu, M.
Deposit date:2017-02-13
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase
Biochem. Biophys. Res. Commun., 486, 2017
5TC1
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IN SITU STRUCTURES OF THE GENOME AND GENOME-DELIVERY APPARATUS IN SSRNA BACTERIOPHAGE MS2
Descriptor:Capsid protein, Maturation protein, phage MS2 genome
Authors:Dai, X.H., Li, Z.H., Lai, M., Shu, S., Du, Y.S., Zhou, Z.H., Sun, R.
Deposit date:2016-09-13
Release date:2016-12-07
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus.
Nature, 541, 2017
3WC9
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND, FSPP
Descriptor:Squalene synthase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-26
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCA
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, FSPP
Descriptor:Farnesyltransferase, putative, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ...
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Oldfield, E., Guo, R.T.
Deposit date:2013-05-26
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCB
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, BPH1237
Descriptor:Farnesyltransferase, putative, hydrogen [(1R)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-hydroxy-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCC
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, E5700
Descriptor:Farnesyltransferase, putative, (3R)-3-({2-benzyl-6-[(3R,4S)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridin-3-yl}ethynyl)-1-azabicyclo[2.2.2]octan-3-ol
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCD
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND, WC-9
Descriptor:Squalene synthase, 2-(4-phenoxyphenoxy)ethyl thiocyanate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCE
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, ER119884
Descriptor:Farnesyltransferase, putative, (3R)-3-{[2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl]ethynyl}-1-azabicyclo[2.2.2]octan-3-ol
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCF
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND,BPH1218
Descriptor:Squalene synthase, hydrogen [(1S)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCG
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, BPH1344
Descriptor:Farnesyltransferase, putative, hydrogen [(1R)-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCH
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND BPH1237
Descriptor:Squalene synthase, hydrogen [(1R)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-hydroxy-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCI
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND,BPH1325
Descriptor:Squalene synthase, hydrogen [(1R)-1-hydroxy-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCJ
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND,E5700
Descriptor:Squalene synthase, (3R)-3-({2-benzyl-6-[(3R,4S)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridin-3-yl}ethynyl)-1-azabicyclo[2.2.2]octan-3-ol
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCL
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND,BPH1344
Descriptor:Squalene synthase, hydrogen [(1R)-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-28
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCM
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND, ER119884
Descriptor:Squalene synthase, (3R)-3-{[2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl]ethynyl}-1-azabicyclo[2.2.2]octan-3-ol
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-28
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
5Y9C
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CRYSTAL STRUCTURE OF HPV58 PENTAMER IN COMPLEX WITH THE FAB FRAGMENT OF ANTIBODY A12A3
Descriptor:Major capsid protein L1, heavy chain of Fab fragment of antibody A12A3, light chain of Fab fragment of antibody A12A3
Authors:Li, S.W., Li, Z.H.
Deposit date:2017-08-24
Release date:2017-10-25
Method:X-RAY DIFFRACTION (3.443 Å)
Cite:Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
5Y9E
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CRYSTAL STRUCTURE OF HPV58 PENTAMER
Descriptor:Major capsid protein L1, GLYCEROL, MAGNESIUM ION
Authors:Li, S.W., Li, Z.H.
Deposit date:2017-08-24
Release date:2017-10-25
Method:X-RAY DIFFRACTION (2.042 Å)
Cite:Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
5Y9F
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CRYSTAL STRUCTURE OF HPV59 PENTAMER IN COMPLEX WITH THE FAB FRAGMENT OF ANTIBODY 28F10
Descriptor:Major capsid protein L1, light chains of Fab fragment of antibody 28F10, heavy chain of Fab fragment of antibody 28F10
Authors:Li, S.W., Li, Z.H.
Deposit date:2017-08-24
Release date:2017-10-25
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
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