Author results

1MX7
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TWO HOMOLOGOUS RAT CELLULAR RETINOL-BINDING PROTEINS DIFFER IN LOCAL STRUCTURE AND FLEXIBILITY
Descriptor:CELLULAR RETINOL-BINDING PROTEIN I, APO
Authors:Lu, J., Cistola, D.P., Li, E.
Deposit date:2002-10-01
Release date:2003-07-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Two Homologous Rat Cellular Retinol-binding Proteins Differ in Local Conformational Flexibility.
J.Mol.Biol., 330, 2003
1MX8
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TWO HOMOLOGOUS RAT CELLULAR RETINOL-BINDING PROTEINS DIFFER IN LOCAL STRUCTURE AND FLEXIBILITY
Descriptor:CELLULAR RETINOL-BINDING PROTEIN I, HOLO, RETINOL
Authors:Lu, J., Cistola, D.P., Li, E.
Deposit date:2002-10-01
Release date:2003-07-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Two homologous rat cellular retinol-binding proteins differ in local conformational flexibility.
J.Mol.Biol., 330, 2003
1EII
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NMR STRUCTURE OF HOLO CELLULAR RETINOL-BINDING PROTEIN II
Descriptor:CELLULAR RETINOL-BINDING PROTEIN II, RETINOL
Authors:Lu, J., Lin, C.L., Tang, C., Ponder, J.W., Kao, J.L., Cistola, D.P., Li, E.
Deposit date:2000-02-25
Release date:2000-08-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Binding of retinol induces changes in rat cellular retinol-binding protein II conformation and backbone dynamics.
J.Mol.Biol., 300, 2000
1B4M
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NMR STRUCTURE OF APO CELLULAR RETINOL-BINDING PROTEIN II, 24 STRUCTURES
Descriptor:CELLULAR RETINOL-BINDING PROTEIN II
Authors:Lu, J., Lin, C.-L., Tang, C., Ponder, J.W., Kao, J.L.F., Cistola, D.P., Li, E.
Deposit date:1998-12-23
Release date:1999-04-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure and dynamics of rat apo-cellular retinol-binding protein II in solution: comparison with the X-ray structure.
J.Mol.Biol., 286, 1999
5XJX
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PRE-FORMED PLANT RECETOR ERL1-TMM COMPLEXE
Descriptor:Protein TOO MANY MOUTHS, LRR receptor-like serine/threonine-protein kinase ERL1
Authors:Chai, J., Lin, G., Zhang, L., Han, Z., Yang, X., Liu, W., Qi, Y., Chang, J., Li, E.
Deposit date:2017-05-04
Release date:2019-01-23
Method:X-RAY DIFFRACTION (3.055 Å)
Cite:A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
4QQN
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PROTEIN ARGININE METHYLTRANSFERASE 3 IN COMPLEX WITH COMPOUND MTV044246
Descriptor:PRMT3 protein, 1-{2-[1-(aminomethyl)cyclohexyl]ethyl}-3-isoquinolin-6-ylurea, GLYCEROL, ...
Authors:Dong, A., Dobrovetsky, E., Tempel, W., He, H., Zhao, K., Smil, D., Landon, M., Luo, X., Chen, Z., Dai, M., Yu, Z., Lin, Y., Zhang, H., Zhao, K., Schapira, M., Brown, P.J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Vedadi, M., Structural Genomics Consortium (SGC)
Deposit date:2014-06-27
Release date:2014-09-17
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3).
J. Med. Chem., 61, 2018
5H19
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EED IN COMPLEX WITH PRC2 ALLOSTERIC INHIBITOR EED162
Descriptor:Polycomb protein EED, Histone-lysine N-methyltransferase EZH2, 5-(furan-2-ylmethylamino)-9-(phenylmethyl)-8,10-dihydro-7H-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile
Authors:Zhao, K., Zhao, M., Luo, X., Zhang, H.
Deposit date:2016-10-08
Release date:2017-01-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
5GSA
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EED IN COMPLEX WITH AN ALLOSTERIC PRC2 INHIBITOR
Descriptor:Polycomb protein EED, Histone-lysine N-methyltransferase EZH2, N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
Authors:Zhao, K., Zhao, M., Luo, X., Zhang, H.
Deposit date:2016-08-15
Release date:2017-02-01
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of
Nat. Chem. Biol., 13, 2017
5H13
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EED IN COMPLEX WITH PRC2 ALLOSTERIC INHIBITOR EED396
Descriptor:Polycomb protein EED, GLYCEROL, PRASEODYMIUM ION, ...
Authors:Zhao, K., Zhao, M., Luo, X., Zhang, H.
Deposit date:2016-10-08
Release date:2017-01-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
5H14
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EED IN COMPLEX WITH AN ALLOSTERIC PRC2 INHIBITOR EED666
Descriptor:Polycomb protein EED, Histone-lysine N-methyltransferase EZH2, GLYCEROL, ...
Authors:Zhao, K., Zhao, M., Luo, X., Zhang, H.
Deposit date:2016-10-08
Release date:2017-01-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
5H15
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EED IN COMPLEX WITH PRC2 ALLOSTERIC INHIBITOR EED709
Descriptor:Polycomb protein EED, Histone-lysine N-methyltransferase EZH2, (3R,4S)-1-[(2-methoxyphenyl)methyl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine
Authors:Zhao, K., Zhao, M., Luo, X., Zhang, H.
Deposit date:2016-10-08
Release date:2017-01-25
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
5H17
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EED IN COMPLEX WITH PRC2 ALLOSTERIC INHIBITOR EED210
Descriptor:Polycomb protein EED, Histone-lysine N-methyltransferase EZH2, (3R,4aS,10aS)-6-methoxy-3-[(3-methoxyphenyl)methyl]-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline
Authors:Zhao, K., Zhao, M., Luo, X., Zhang, H.
Deposit date:2016-10-08
Release date:2017-01-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
1F03
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SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C
Descriptor:CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Wu, Y.B., Lu, J., Qian, C.M., Tang, W.X., Li, E.C., Wang, J.F., Wang, Y.H., Wang, W.H., Lu, J.X., Xie, Y., Huang, Z.X.
Deposit date:2000-05-14
Release date:2000-06-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c.
Eur.J.Biochem., 268, 2001
1F04
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SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C
Descriptor:CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Wu, Y.B., Lu, J., Qian, C.M., Tang, W.X., Li, E.C., Wang, J.F., Wang, Y.H., Wang, W.H., Lu, J.X., Xie, Y., Huang, Z.X.
Deposit date:2000-05-14
Release date:2000-06-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c.
Eur.J.Biochem., 268, 2001
3TG4
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STRUCTURE OF SMYD2 IN COMPLEX WITH SAM
Descriptor:N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ZINC ION, ...
Authors:Zhao, K., Wang, L.
Deposit date:2011-08-17
Release date:2011-08-31
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation
J.Biol.Chem., 2011
3TG5
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STRUCTURE OF SMYD2 IN COMPLEX WITH P53 AND SAH
Descriptor:N-lysine methyltransferase SMYD2, Cellular tumor antigen p53, GLYCEROL, ...
Authors:Zhao, K., Wang, L.
Deposit date:2011-08-17
Release date:2011-08-31
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation
J.Biol.Chem., 2011
5WUK
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CRYSTAL STRUCTURE OF EED [G255D] IN COMPLEX WITH EZH2 PEPTIDE AND EED226 COMPOUND
Descriptor:Polycomb protein EED, Histone-lysine N-methyltransferase EZH2, GLYCEROL, ...
Authors:Chen, Z.
Deposit date:2016-12-19
Release date:2017-05-03
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Split luciferase-based biosensors for characterizing EED binders
Anal. Biochem., 522, 2017
5XPI
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STRUCTURE OF UHRF1 TTD IN COMPLEX WITH NV01
Descriptor:E3 ubiquitin-protein ligase UHRF1, N-[3-(diethylamino)propyl]-2-(12-methyl-9-oxidanylidene-5-thia-1,10,11-triazatricyclo[6.4.0.0^2,6]dodeca-2(6),3,7,11-tetraen-10-yl)ethanamide
Authors:Luo, X., Zhao, K.
Deposit date:2017-06-02
Release date:2018-04-25
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain
SLAS Discov, 23, 2018
3T9T
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CRYSTAL STRUCTURE OF BTK MUTANT (F435T,K596R) COMPLEXED WITH IMIDAZO[1,5-A]QUINOXALINE
Descriptor:Tyrosine-protein kinase ITK/TSK, (2Z)-4-(dimethylamino)-N-{7-fluoro-4-[(2-methylphenyl)amino]imidazo[1,5-a]quinoxalin-8-yl}-N-methylbut-2-enamide, GLYCEROL
Authors:Han, S., Caspers, N.
Deposit date:2011-08-03
Release date:2011-10-12
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis.
Bioorg.Med.Chem.Lett., 21, 2011
5XJO
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PLANT RECEPTOR ERL1-TMM IN COMPLEX WITH PEPTIDE EPF1
Descriptor:LRR receptor-like serine/threonine-protein kinase ERL1, Protein EPIDERMAL PATTERNING FACTOR 1, Protein TOO MANY MOUTHS
Authors:Chai, J., Lin, G., Zhang, L., Han, Z., Shpak, E.D., Yang, X.
Deposit date:2017-05-03
Release date:2019-01-23
Method:X-RAY DIFFRACTION (2.626 Å)
Cite:A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
5XKJ
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CRYSTAL STRUCTURE OF PLANT RECEPTOR ERL1-TMM IN COMPLEXE WITH EPF2
Descriptor:Protein TOO MANY MOUTHS, Protein EPIDERMAL PATTERNING FACTOR 2, LRR receptor-like serine/threonine-protein kinase ERL1
Authors:Chai, J., Lin, G.
Deposit date:2017-05-07
Release date:2019-01-23
Method:X-RAY DIFFRACTION (3.475 Å)
Cite:A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
5XKN
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CRYSTAL STRUCTURE OF PLANT RECEPTOR ERL2 IN COMPLEXE WITH EPFL4
Descriptor:EPIDERMAL PATTERNING FACTOR-like protein 4, LRR receptor-like serine/threonine-protein kinase ERL2
Authors:Chai, J., Lin, G.
Deposit date:2017-05-08
Release date:2019-01-23
Method:X-RAY DIFFRACTION (3.651 Å)
Cite:A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017