Author results

1FC3
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THE CRYSTAL STRUCTURE OF TRANS-ACTIVATION DOMAIN OF THE SPORULATION RESPONSE REGULATOR, SPO0A
Descriptor:SPO0A
Authors:Lewis, R.J., Krzywda, S., Wilkinson, A.J.
Deposit date:2000-07-17
Release date:2000-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The trans-activation domain of the sporulation response regulator Spo0A revealed by X-ray crystallography.
Mol.Microbiol., 38, 2000
1B0N
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SINR PROTEIN/SINI PROTEIN COMPLEX
Descriptor:PROTEIN (SINR PROTEIN), PROTEIN (SINI PROTEIN), ZINC ION
Authors:Lewis, R.J., Brannigan, J.A., Offen, W.A., Smith, I., Wilkinson, A.J.
Deposit date:1998-11-11
Release date:1999-01-13
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex.
J.Mol.Biol., 283, 1998
1DZ3
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DOMAIN-SWAPPING IN THE SPORULATION RESPONSE REGULATOR SPO0A
Descriptor:Stage 0 sporulation protein A, SULFATE ION
Authors:Lewis, R.J., Brannigan, J.A., Muchova, K., Leonard, G., Barak, I., Wilkinson, A.J.
Deposit date:2000-02-15
Release date:2000-04-10
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Domain swapping in the sporulation response regulator Spo0A.
J. Mol. Biol., 297, 2000
1QMP
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PHOSPHORYLATED ASPARTATE IN THE CRYSTAL STRUCTURE OF THE SPORULATION RESPONSE REGULATOR, SPO0A
Descriptor:Stage 0 sporulation protein A, CALCIUM ION
Authors:Lewis, R.J., Brannigan, J.A., Muchova, K., Barak, I., Wilkinson, A.J.
Deposit date:1999-10-04
Release date:1999-11-14
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Phosphorylated aspartate in the structure of a response regulator protein.
J. Mol. Biol., 294, 1999
6GQA
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CELL DIVISION REGULATOR S. PNEUMONIAE GPSB
Descriptor:Cell cycle protein GpsB
Authors:Lewis, R.J., Rutter, Z.J.
Deposit date:2018-06-07
Release date:2019-01-23
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes.
Nat Commun, 10, 2019
6GQN
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CELL DIVISION REGULATOR, S. PNEUMONIAE GPSB, IN COMPLEX WITH PEPTIDE FRAGMENT OF PENICILLIN BINDING PROTEIN PBP2A
Descriptor:Cell cycle protein GpsB, SpPBP2a, SULFATE ION, ...
Authors:Lewis, R.J., Rutter, Z.J.
Deposit date:2018-06-07
Release date:2019-01-23
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes.
Nat Commun, 10, 2019
2VY9
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MOLECULAR ARCHITECTURE OF THE STRESSOSOME, A SIGNAL INTEGRATION AND TRANSDUCTION HUB
Descriptor:ANTI-SIGMA-FACTOR ANTAGONIST
Authors:Marles-Wright, J., Grant, T., Delumeau, O., van Duinen, G., Firbank, S.J., Lewis, P.J., Murray, J.W., Newman, J.A., Quin, M.B., Race, P.R., Rohou, A., Tichelaar, W., van Heel, M., Lewis, R.J.
Deposit date:2008-07-21
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub
Science, 322, 2008
1FSE
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CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS REGULATORY PROTEIN GERE
Descriptor:GERE, GLYCEROL, SULFATE ION
Authors:Ducros, V.M.-A., Lewis, R.J., Verma, C.S., Dodson, E.J., Leonard, G., Turkenburg, J.P., Murshudov, G.N., Wilkinson, A.J., Brannigan, J.A.
Deposit date:2000-09-08
Release date:2001-03-21
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of GerE, the ultimate transcriptional regulator of spore formation in Bacillus subtilis.
J.Mol.Biol., 306, 2001
1TT3
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NMR SOULUTION STRUCTURE OF OMEGA-CONOTOXIN [K10]MVIIA
Descriptor:Omega-conotoxin MVIIa
Authors:Adams, D.J., Smith, A.B., Schroeder, C.I., Yasuda, T., Lewis, R.J.
Deposit date:2004-06-21
Release date:2004-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
J.Biol.Chem., 278, 2003
1TTK
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NMR SOLUTION STRUCTURE OF OMEGA-CONOTOXIN MVIIA, A N-TYPE CALCIUM CHANNEL BLOCKER
Descriptor:Omega-conotoxin MVIIa
Authors:Adams, D.J., Smith, A.B., Schroeder, C.I., Yasuda, T., Lewis, R.J.
Deposit date:2004-06-22
Release date:2004-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
J.Biol.Chem., 278, 2003
2MHK
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E. COLI LPOA N-TERMINAL DOMAIN
Descriptor:Penicillin-binding protein activator LpoA
Authors:Jean, N.L., Bougault, C., Lodge, A., Derouaux, A., Callens, G., Egan, A., Lewis, R.J., Vollmer, W., Simorre, J.
Deposit date:2013-11-26
Release date:2014-06-25
Last modified:2014-07-23
Method:SOLUTION NMR
Cite:Elongated Structure of the Outer-Membrane Activator of Peptidoglycan Synthesis LpoA: Implications for PBP1A Stimulation.
Structure, 22, 2014
1A0M
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1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI
Descriptor:ALPHA-CONOTOXIN [TYR15]-EPI
Authors:Hu, S.-H., Loughnan, M., Miller, R., Weeks, C.M., Blessing, R.H., Alewood, P.F., Lewis, R.J., Martin, J.L.
Deposit date:1997-12-03
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The 1.1 A resolution crystal structure of [Tyr15]EpI, a novel alpha-conotoxin from Conus episcopatus, solved by direct methods.
Biochemistry, 37, 1998
1A39
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HUMICOLA INSOLENS ENDOCELLULASE EGI S37W, P39W DOUBLE-MUTANT
Descriptor:ENDOGLUCANASE I, N-ACETYL-D-GLUCOSAMINE
Authors:Davies, G.J., Ducros, V., Lewis, R.J., Borchert, T.V., Schulein, M.
Deposit date:1998-01-28
Release date:1999-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Oligosaccharide specificity of a family 7 endoglucanase: insertion of potential sugar-binding subsites.
J.Biotechnol., 57, 1997
1AV3
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POTASSIUM CHANNEL BLOCKER KAPPA CONOTOXIN PVIIA FROM C. PURPURASCENS, NMR, 20 STRUCTURES
Descriptor:KAPPA-PVIIA
Authors:Scanlon, M.J., Naranjo, D., Thomas, L., Alewood, P.F., Lewis, R.J., Craik, D.J.
Deposit date:1997-09-24
Release date:1998-10-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA.
Structure, 5, 1997
1CNN
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OMEGA-CONOTOXIN MVIIC FROM CONUS MAGUS
Descriptor:OMEGA-CONOTOXIN MVIIC
Authors:Nielsen, K.J., Adams, D., Thomas, L., Bond, T., Alewood, P.F., Craik, D.J., Lewis, R.J.
Deposit date:1999-05-20
Release date:2000-05-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels.
J.Mol.Biol., 289, 1999
1E3A
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A SLOW PROCESSING PRECURSOR PENICILLIN ACYLASE FROM ESCHERICHIA COLI
Descriptor:PENICILLIN AMIDASE ALPHA SUBUNIT, PENICILLIN AMIDASE BETA SUBUNIT, CALCIUM ION, ...
Authors:Hewitt, L., Kasche, V., Lummer, K., Lewis, R.J., Murshudov, G.N., Verma, C.S., Dodson, G.G., Wilson, K.S.
Deposit date:2000-06-07
Release date:2000-11-29
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a Slow Processing Precursor Penicillin Acylase from Escherichia Coli Reveals the Linker Peptide Blocking the Active-Site Cleft
J.Mol.Biol., 302, 2000
1H4X
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STRUCTURE OF THE BACILLUS CELL FATE DETERMINANT SPOIIAA IN THE PHOSPHORYLATED FORM
Descriptor:ANTI-SIGMA F FACTOR ANTAGONIST, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Seavers, P.R., Lewis, R.J., Brannigan, J.A., Verschueren, K.H.G., Murshudov, G.N., Wilkinson, A.J.
Deposit date:2001-05-15
Release date:2001-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structure of the Bacillus Cell Fate Determinant Spoiiaa in Phosphorylated and Unphosphorylated Forms
Structure, 9, 2001
1H4Y
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STRUCTURE OF THE ANTI-SIGMA FACTOR ANTAGONIST SPOIIAA IN ITS UNPHOSPHORYLATED FORM
Descriptor:ANTI-SIGMA F FACTOR ANTAGONIST
Authors:Seavers, P.R., Lewis, R.J., Brannigan, J.A., Verschueren, K.H.G., Murshudov, G.N., Wilkinson, A.J.
Deposit date:2001-05-16
Release date:2001-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structure of the Bacillus Cell Fate Determinant Spoiiaa in Phosphorylated and Unphosphorylated Forms
Structure, 9, 2001
1H4Z
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STRUCTURE OF THE ANTI-SIGMA FACTOR ANTAGONIST SPOIIAA IN ITS UNPHOSPHORYLATED FORM
Descriptor:ANTI-SIGMA F FACTOR ANTAGONIST
Authors:Seavers, P.R., Lewis, R.J., Brannigan, J.A., Verschueren, K.H.G., Murshudov, G.N., Wilkinson, A.J.
Deposit date:2001-05-16
Release date:2001-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structure of the Bacillus Cell Fate Determinant Spoiiaa in Phosphorylated and Unphosphorylated Forms
Structure, 9, 2001
1IEN
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SOLUTION STRUCTURE OF TIA
Descriptor:PROTEIN TIA
Authors:Sharpe, I.A., Gehrmann, J., Loughnan, M.L., Thomas, L., Adams, D.A., Atkins, A., Palant, E., Craik, D.J., Adams, D.J., Alewood, P.F., Lewis, R.J.
Deposit date:2001-04-10
Release date:2002-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nat.Neurosci., 4, 2001
1IEO
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SOLUTION STRUCTURE OF MRIB-NH2
Descriptor:PROTEIN MRIB-NH2
Authors:Sharpe, I.A., Gehrmann, J., Loughnan, M.L., Thomas, L., Adams, D.A., Atkins, A., Palant, E., Craik, D.J., Adams, D.J., Alewood, P.F., Lewis, R.J.
Deposit date:2001-04-10
Release date:2002-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nat.Neurosci., 4, 2001
1MTQ
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF ALPHA-CONOTOXIN GID BY NMR SPECTROSCOPY
Descriptor:alpha-conotoxin GID
Authors:Nicke, A., Loughnan, M.L., Millard, E.L., Alewood, P.F., Adams, D.J., Daly, N.L., Craik, D.J., Lewis, R.J.
Deposit date:2002-09-22
Release date:2003-02-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Isolation, Structure, and Activity of GID, a Novel alpha 4/7-Conotoxin with an Extended N-terminal Sequence
J.BIOL.CHEM., 278, 2003
1MVI
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N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA, NMR, 15 STRUCTURES
Descriptor:MVIIA
Authors:Nielsen, K.J., Thomas, L., Lewis, R.J., Alewood, P.F., Craik, D.J.
Deposit date:1996-08-02
Release date:1997-08-12
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.
J.Mol.Biol., 263, 1996
1MVJ
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N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA NMR, 15 STRUCTURES
Descriptor:SVIB
Authors:Nielsen, K.J., Thomas, L., Lewis, R.J., Alewood, P.F., Craik, D.J.
Deposit date:1996-08-02
Release date:1997-08-12
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.
J.Mol.Biol., 263, 1996
1ONT
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NMDA RECEPTOR ANTAGONIST, CONANTOKIN-T, NMR, 17 STRUCTURES
Descriptor:CONANTOKIN-T
Authors:Skjaerbaek, N., Nielsen, K.J., Lewis, R.J., Alewood, P.F., Craik, D.J.
Deposit date:1996-08-27
Release date:1997-09-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
J.Biol.Chem., 272, 1997