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5WUV
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CRYSTAL STRUCTURE OF CERTOLIZUMAB FAB
Descriptor:light chain, heavy chain
Authors:Heo, Y.S., Lee, J.U., Son, J.Y., Shin, W., Yoo, K.Y.
Deposit date:2016-12-21
Release date:2017-06-07
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Int J Mol Sci, 18, 2017
5WUX
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TNFALPHA-CERTOLIZUMAB FAB
Descriptor:heavy, light, Tumor necrosis factor alpha
Authors:Heo, Y.S., Lee, J.U.
Deposit date:2016-12-21
Release date:2017-06-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Int J Mol Sci, 18, 2017
5GGQ
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CRYSTAL STRUCTURE OF NIVOLUMAB FAB FRAGMENT
Descriptor:nivolumab light chain, nivolumab heavy chain
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGR
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PD-1 IN COMPLEX WITH NIVOLUMAB FAB
Descriptor:heavy chain, light chain, Programmed cell death protein 1
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGS
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PD-1 IN COMPLEX WITH PEMBROLIZUMAB FAB
Descriptor:heavy chain, light chain, Programmed cell death protein 1
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGT
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PD-L1 IN COMPLEX WITH BMS-936559 FAB
Descriptor:Programmed cell death 1 ligand 1, IgG H chain, IGK@ protein
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGU
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CRYSTAL STRUCTURE OF TREMELIMUMAB FAB
Descriptor:heavy chain, light chain
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.292 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5GGV
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CTLA-4 IN COMPLEX WITH TREMELIMUMAB FAB
Descriptor:light chain, heavy chain, Cytotoxic T-lymphocyte protein 4
Authors:Heo, Y.S.
Deposit date:2016-06-16
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
5Y9J
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BAFF IN COMPLEX WITH BELIMUMAB
Descriptor:belibumab light chain, belimumab heavy chain, Tumor necrosis factor ligand superfamily member 13B
Authors:Heo, Y.-S., Shin, W.
Deposit date:2017-08-25
Release date:2018-02-21
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Nat Commun, 9, 2018
5Y9K
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STRUCTURE OF THE BELIMUMAB FAB FRAGMENT
Descriptor:belimumab light chain, belimumab heavy chain
Authors:Heo, Y.-S., Shin, W.
Deposit date:2017-08-25
Release date:2018-02-21
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Nat Commun, 9, 2018
4Y7I
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CRYSTAL STRUCTURE OF MTMR8
Descriptor:Myotubularin-related protein 8, PHOSPHATE ION
Authors:Yoo, K., Lee, J., Son, J., Shin, W., Im, D., Heo, Y.S.
Deposit date:2015-02-15
Release date:2015-07-15
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structure of the catalytic phosphatase domain of MTMR8: implications for dimerization, membrane association and reversible oxidation.
Acta Crystallogr.,Sect.D, 71, 2015
169963
PDB entries from 2020-10-14