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3FV5
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Crystal Structure of E. coli Topoisomerase IV co-complexed with inhibitor
Descriptor: 1-(4-acetyl-6-pyridin-3-yl-1H-benzimidazol-2-yl)-3-ethylurea, DNA topoisomerase 4 subunit B
Authors:Wei, Y, Charifson, P, LeTiran, A.
Deposit date:2009-01-15
Release date:2010-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design and syntheses of novel C7-derived-aminobenzimidazole ureas: bacterial gyrase/topoisomerase IV inhibitors with potent Gram-positve antibacterial activity
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