Author results

1MR4
  • Download 1mr4
  • View 1mr4
Molmil generated image of 1mr4
SOLUTION STRUCTURE OF NAD1 FROM NICOTIANA ALATA
Descriptor:Nicotiana alata plant defensin 1 (NaD1)
Authors:Lay, F.T., Schirra, H.J., Scanlon, M.J., Anderson, M.A., Craik, D.J.
Deposit date:2002-09-18
Release date:2003-09-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Three-dimensional Solution Structure of NaD1, a New Floral Defensin from Nicotiana alata and its Application to a Homology Model of the Crop Defense Protein alfAFP
J.MOL.BIOL., 325, 2003
4AAZ
  • Download 4aaz
  • View 4aaz
Molmil generated image of 4aaz
X-RAY STRUCTURE OF NICOTIANA ALATA DEFENSIN 1 NAD1
Descriptor:FLOWER-SPECIFIC DEFENSIN, 1,2-ETHANEDIOL, PHOSPHATE ION
Authors:Lay, F.T., Mills, G.D., Hulett, M.D., Kvansakul, M.
Deposit date:2011-12-06
Release date:2012-04-25
Last modified:2012-08-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity.
J.Biol.Chem., 287, 2012
4AB0
  • Download 4ab0
  • View 4ab0
Molmil generated image of 4ab0
X-RAY CRYSTAL STRUCTURE OF NICOTIANA ALATA DEFENSIN NAD1
Descriptor:FLOWER-SPECIFIC DEFENSIN, PHOSPHATE ION
Authors:Mills, G.D., Lay, F.T., Hulett, M.D., Kvansakul, M.
Deposit date:2011-12-06
Release date:2012-04-25
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.636 Å)
Cite:Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity.
J.Biol.Chem., 287, 2012
4CQK
  • Download 4cqk
  • View 4cqk
Molmil generated image of 4cqk
CRYSTAL STRUCTURE OF LIGAND-BOUND NAD1
Descriptor:FLOWER-SPECIFIC DEFENSIN, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, SULFATE ION, ...
Authors:Lay, F.T., Mills, G.M., Poon, I.K.H., Baxter, A.A., Hulett, M.D., Kvansakul, M.
Deposit date:2014-02-17
Release date:2014-04-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Phosphoinositide-Mediated Oligomerization of a Defensin Induces Cell Lysis.
Elife, 3, 2014
1N4N
  • Download 1n4n
  • View 1n4n
Molmil generated image of 1n4n
STRUCTURE OF THE PLANT DEFENSIN PHD1 FROM PETUNIA HYBRIDA
Descriptor:floral defensin-like protein 1
Authors:Janssen, B.J.C., Schirra, H.J., Lay, F.T., Anderson, M.A., Craik, D.J.
Deposit date:2002-11-01
Release date:2003-11-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds
Biochemistry, 42, 2003
4UJ0
  • Download 4uj0
  • View 4uj0
Molmil generated image of 4uj0
CRYSTAL STRUCTURE OF THE TOMATO DEFENSIN TPP3
Descriptor:FLOWER-SPECIFIC GAMMA-THIONIN-LIKE PROTEIN/ACIDIC PROTEIN, ACETATE ION
Authors:Richter, V., Lay, F.T., Hulett, M.D., Kvansakul, M.
Deposit date:2015-04-07
Release date:2015-04-15
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Tomato Defensin Tpp3 Binds Phosphatidylinositol (4,5)-Bisphosphate Via a Conserved Dimeric Cationic Grip Conformation to Mediate Cell Lysis.
Mol.Cell.Biol., 35, 2015
5KK4
  • Download 5kk4
  • View 5kk4
Molmil generated image of 5kk4
CRYSTAL STRUCTURE OF THE PLANT DEFENSIN NSD7 BOUND TO PHOSPHATIDIC ACID
Descriptor:NsD7, 1,2-ETHANEDIOL, SULFATE ION, ...
Authors:Kvansakul, M., Hulett, M.D., Lay, F.T.
Deposit date:2016-06-21
Release date:2016-10-05
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.
Proc.Natl.Acad.Sci.USA, 113, 2016
5VYP
  • Download 5vyp
  • View 5vyp
Molmil generated image of 5vyp
CRYSTAL STRUCTURE OF THE PLANT DEFENSIN NSD7 BOUND TO PIP2
Descriptor:Defensin NsD7, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, SULFATE ION, ...
Authors:Jarva, M., Lay, F.T., Hulett, M., Kvansakul, M.
Deposit date:2017-05-25
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type.
FEBS Lett., 591, 2017
6B55
  • Download 6b55
  • View 6b55
Molmil generated image of 6b55
CRYSTAL STRUCTURE OF THE PLANT DEFENSIN NAD1 COMPLEXED WITH PHOSPHATIDIC ACID
Descriptor:Flower-specific defensin, 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, PHOSPHATE ION, ...
Authors:Jarva, M., Phan, K., Humble, C., Lay, F.T., Hulett, M., Kvansakul, M.
Deposit date:2017-09-28
Release date:2018-05-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.
Nat Commun, 9, 2018
6CS9
  • Download 6cs9
  • View 6cs9
Molmil generated image of 6cs9
CRYSTAL STRUCTURE OF HUMAN BETA-DEFENSIN 2 IN COMPLEX WITH PIP2
Descriptor:Beta-defensin 4A, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Jarva, M., Phan, K., Lay, F.T., Humble, C., Hulett, M., Kvansakul, M.
Deposit date:2018-03-20
Release date:2018-07-25
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Human beta-defensin 2 killsCandida albicansthrough phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization.
Sci Adv, 4, 2018