Author results

4X21
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THE MAP KINASE JNK3 AS TARGET FOR HALOGEN BONDING
分子名称:Mitogen-activated protein kinase 10, N-ethyl-4-{[4-(1H-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamide, CHLORIDE ION
著者Lange, A., Buettner, F.M., Guenther, M.B., Zimmermann, M.O., Hennig, S., Laufer, S.A., Stehle, T., Boeckler, F.
登録日2014-11-25
公開日2015-11-11
最終更新日2015-12-02
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond.
J.Am.Chem.Soc., 137, 2015
1XSW
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THE SOLID-STATE NMR STRUCTURE OF KALIOTOXIN
分子名称:Kaliotoxin 1
著者Lange, A., Becker, S., Seidel, K., Giller, K., Pongs, O., Baldus, M.
登録日2004-10-20
公開日2005-04-05
最終更新日2011-07-13
実験手法SOLID-STATE NMR
主引用文献A Concept for Rapid Protein-Structure Determination by Solid-State NMR Spectroscopy
Angew.Chem.Int.Ed.Engl., 44, 2005
2L0T
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SOLUTION STRUCTURE OF THE COMPLEX OF UBIQUITIN AND THE VHS DOMAIN OF STAM2
分子名称:Ubiquitin, Signal transducing adapter molecule 2
著者Lange, A., Hoeller, D., Wienk, H., Marcillat, O., Lancelin, J., Walker, O.
登録日2010-07-15
公開日2010-12-15
最終更新日2012-03-14
実験手法SOLUTION NMR
主引用文献NMR reveals a different mode of binding of the Stam2 VHS domain to ubiquitin and diubiquitin.
Biochemistry, 50, 2011
2KJ3
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HIGH-RESOLUTION STRUCTURE OF THE HET-S(218-289) PRION IN ITS AMYLOID FORM OBTAINED BY SOLID-STATE NMR
分子名称:Small s protein
著者Van Melckebeke, H., Wasmer, C., Lange, A., AB, E., Loquet, A., Meier, B.H.
登録日2009-05-20
公開日2010-06-02
最終更新日2011-07-13
実験手法SOLID-STATE NMR
主引用文献Atomic-Resolution Three-Dimensional Structure of HET-s(218-289) Amyloid Fibrils by Solid-State NMR Spectroscopy
J.Am.Chem.Soc., 132, 2010
2KV7
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NMR SOLUTION STRUCTURE OF A SOLUBLE PRGI MUTANT FROM SALMONELLA TYPHIMURIUM
分子名称:Protein prgI
著者Schmidt, H., Poyraz, O., Seidel, K., Delissen, F., Ader, C., Tenenboim, H., Goosmann, C., Laube, B., Thuenemann, A.F., Zychlinski, A., Baldus, M., Lange, A., Griesinger, C., Kolbe, M.
登録日2010-03-09
公開日2010-06-16
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Protein refolding is required for assembly of the type three secretion needle
Nat.Struct.Mol.Biol., 2010
2LPZ
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ATOMIC MODEL OF THE TYPE-III SECRETION SYSTEM NEEDLE
分子名称:Protein prgI
著者Loquet, A., Sgourakis, N.G., Gupta, R., Giller, K., Riedel, D., Goosmann, C., Griesinger, C., Kolbe, M.G., Baker, D., Becker, S., Lange, A.
登録日2012-02-21
公開日2012-05-16
最終更新日2012-06-27
実験手法SOLID-STATE NMR
主引用文献Atomic model of the type III secretion system needle.
Nature, 486, 2012
2MEX
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STRUCTURE OF THE TETRAMERIC BUILDING BLOCK OF THE SALMONELLA TYPHIMURIUM PRGI TYPE THREE SECRETION SYSTEM NEEDLE
分子名称:Protein PrgI
著者Loquet, A., Habenstein, B., Chevelkov, V., Giller, K., Becker, S., Lange, A.
登録日2013-10-01
公開日2013-12-25
最終更新日2014-01-15
実験手法SOLID-STATE NMR
主引用文献Atomic structure and handedness of the building block of a biological assembly.
J.Am.Chem.Soc., 135, 2013
2MME
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HYBRID STRUCTURE OF THE SHIGELLA FLEXNERI MXIH TYPE THREE SECRETION SYSTEM NEEDLE
分子名称:MxiH
著者Demers, J.P., Habenstein, B., Loquet, A., Vasa, S.K., Becker, S., Baker, D., Lange, A., Sgourakis, N.G.
登録日2014-03-14
公開日2014-10-08
実験手法SOLID-STATE NMR (7.7 Å), ELECTRON MICROSCOPY
主引用文献High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy.
Nat Commun, 5, 2014
2MSG
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SOLID-STATE NMR STRUCTURE OF UBIQUITIN
分子名称:Ubiquitin
著者Lakomek, N., Habenstein, B., Loquet, A., Shi, C., Giller, K., Wolff, S., Becker, S., Fasshuber, H., Lange, A.
登録日2014-08-04
公開日2015-02-18
最終更新日2015-05-13
実験手法SOLID-STATE NMR
主引用文献Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR.
Protein Sci., 24, 2015
2N7H
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HYBRID STRUCTURE OF THE TYPE 1 PILUS OF UROPATHOGENIC E.COLI
分子名称:FimA
著者Habenstein, B., Loquet, A., Giller, K., Vasa, S., Becker, S., Habeck, M., Lange, A.
登録日2015-09-11
公開日2015-09-23
最終更新日2015-10-14
実験手法SOLID-STATE NMR
主引用文献Hybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coli.
Angew.Chem.Int.Ed.Engl., 54, 2015
2X9C
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CRYSTAL STRUCTURE OF A SOLUBLE PRGI MUTANT FROM SALMONELLA TYPHIMURIUM
分子名称:PROTEIN PRGI
著者Poyraz, O., Schmidt, H., Seidel, K., Delissen, F., Ader, C., Tenenboim, H., Goosmann, C., Laube, B., Thuenemann, A.F., Zychlinsky, A., Baldus, M., Lange, A., Griesinger, C., Kolbe, M.
登録日2010-03-15
公開日2010-06-16
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Protein Refolding is Required for Assembly of the Type Three Secretion Needle
Nat.Struct.Mol.Biol., 17, 2010
2RNM
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STRUCTURE OF THE HET-S(218-289) PRION IN ITS AMYLOID FORM OBTAINED BY SOLID-STATE NMR
分子名称:Small s protein
著者Wasmer, C., Lange, A., Van Melckebeke, H., Siemer, A., Riek, R., Meier, B.H.
登録日2008-01-24
公開日2008-04-01
最終更新日2015-07-08
実験手法SOLUTION NMR
主引用文献Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core
Science, 319, 2008
1UN0
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CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN COMPLEX WITH A NUP2P N-TERMINAL FRAGMENT
分子名称:IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2
著者Matsuura, Y., Lange, A., Harreman, M.T., Corbett, A.H., Stewart, M.
登録日2003-09-03
公開日2003-10-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for Nup2P Function in Cargo Release and Karyopherin Recycling in Nuclear Import
Embo J., 22, 2003
2N3D
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ATOMIC STRUCTURE OF THE CYTOSKELETAL BACTOFILIN BACA REVEALED BY SOLID-STATE NMR
分子名称:Bactofilin A
著者Shi, C., Fricke, P., Lin, L., Chevelkov, V., Wegstroth, M., Giller, K., Becker, S., Thanbichler, M., Lange, A.
登録日2015-05-29
公開日2015-12-16
最終更新日2016-02-03
実験手法SOLID-STATE NMR
主引用文献Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR.
Sci Adv, 1, 2015
2UVS
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HIGH RESOLUTION SOLID-STATE NMR STRUCTURE OF KALIOTOXIN
分子名称:POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.1
著者Korukottu, J., Lange, A., Vijayan, V., Schneider, R., Pongs, O., Becker, S., Baldus, M., Zweckstetter, M.
登録日2007-03-14
公開日2008-05-27
最終更新日2011-07-13
実験手法SOLID-STATE NMR
主引用文献Conformational Plasticity in Ion Channel Recognition of a Peptide Toxin
To be Published
3JC8
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ARCHITECTURAL MODEL OF THE TYPE IVA PILUS MACHINE IN A PILIATED STATE
分子名称:PilA, Type IV-A pilus assembly ATPase PilB, Type 4 fimbrial assembly protein PilC, ...
著者Chang, Y.-W., Rettberg, L.A., Jensen, G.J.
登録日2015-11-24
公開日2016-03-16
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY
主引用文献Architecture of the type IVa pilus machine.
Science, 351, 2016
3JC9
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ARCHITECTURAL MODEL OF THE TYPE IVA PILUS MACHINE IN A NON-PILIATED STATE
分子名称:PilA, PilC, PilN, ...
著者Chang, Y.-W., Rettberg, L.A., Jensen, G.J.
登録日2015-11-24
公開日2016-03-16
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY
主引用文献Architecture of the type IVa pilus machine.
Science, 351, 2016
3ND2
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STRUCTURE OF YEAST IMPORTIN-BETA (KAP95P)
分子名称:Importin subunit beta-1
著者Forwood, J.K., Kobe, B.
登録日2010-06-06
公開日2010-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Quantitative Structural Analysis of Importin-beta Flexibility: Paradigm for Solenoid Protein Structures
Structure, 18, 2010
2MUS
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HADDOCK CALCULATED MODEL OF LIN5001 BOUND TO THE HET-S AMYLOID
分子名称:Heterokaryon incompatibility protein s, 3''',4'-bis(carboxymethyl)-2,2':5',2'':5'',2''':5''',2''''-quinquethiophene-5,5''''-dicarboxylic acid
著者Hermann, U.S., Schuetz, A.K., Shirani, H., Saban, D., Nuvolone, M., Huang, D.H., Li, B., Ballmer, B., Aslund, A.K.O., Mason, J.J., Rushing, E., Budka, H., Hammarstrom, P., Bockmann, A., Caflisch, A., Meier, B.H., Nilsson, P.K.R., Hornemann, S., Aguzzi, A.
登録日2014-09-16
公開日2017-02-01
最終更新日2018-06-13
実験手法SOLUTION NMR
主引用文献Structure-based drug design identifies polythiophenes as antiprion compounds.
Sci Transl Med, 7, 2015