Author results

4X21
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THE MAP KINASE JNK3 AS TARGET FOR HALOGEN BONDING
Descriptor:Mitogen-activated protein kinase 10, N-ethyl-4-{[4-(1H-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamide, CHLORIDE ION
Authors:Lange, A., Buettner, F.M., Guenther, M.B., Zimmermann, M.O., Hennig, S., Laufer, S.A., Stehle, T., Boeckler, F.
Deposit date:2014-11-25
Release date:2015-11-11
Last modified:2015-12-02
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond.
J.Am.Chem.Soc., 137, 2015
1XSW
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THE SOLID-STATE NMR STRUCTURE OF KALIOTOXIN
Descriptor:Kaliotoxin 1
Authors:Lange, A., Becker, S., Seidel, K., Giller, K., Pongs, O., Baldus, M.
Deposit date:2004-10-20
Release date:2005-04-05
Last modified:2011-07-13
Method:SOLID-STATE NMR
Cite:A Concept for Rapid Protein-Structure Determination by Solid-State NMR Spectroscopy
Angew.Chem.Int.Ed.Engl., 44, 2005
2L0T
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SOLUTION STRUCTURE OF THE COMPLEX OF UBIQUITIN AND THE VHS DOMAIN OF STAM2
Descriptor:Ubiquitin, Signal transducing adapter molecule 2
Authors:Lange, A., Hoeller, D., Wienk, H., Marcillat, O., Lancelin, J., Walker, O.
Deposit date:2010-07-15
Release date:2010-12-15
Last modified:2012-03-14
Method:SOLUTION NMR
Cite:NMR reveals a different mode of binding of the Stam2 VHS domain to ubiquitin and diubiquitin.
Biochemistry, 50, 2011
2KJ3
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HIGH-RESOLUTION STRUCTURE OF THE HET-S(218-289) PRION IN ITS AMYLOID FORM OBTAINED BY SOLID-STATE NMR
Descriptor:Small s protein
Authors:Van Melckebeke, H., Wasmer, C., Lange, A., AB, E., Loquet, A., Meier, B.H.
Deposit date:2009-05-20
Release date:2010-06-02
Last modified:2011-07-13
Method:SOLID-STATE NMR
Cite:Atomic-Resolution Three-Dimensional Structure of HET-s(218-289) Amyloid Fibrils by Solid-State NMR Spectroscopy
J.Am.Chem.Soc., 132, 2010
2KV7
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NMR SOLUTION STRUCTURE OF A SOLUBLE PRGI MUTANT FROM SALMONELLA TYPHIMURIUM
Descriptor:Protein prgI
Authors:Schmidt, H., Poyraz, O., Seidel, K., Delissen, F., Ader, C., Tenenboim, H., Goosmann, C., Laube, B., Thuenemann, A.F., Zychlinski, A., Baldus, M., Lange, A., Griesinger, C., Kolbe, M.
Deposit date:2010-03-09
Release date:2010-06-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Protein refolding is required for assembly of the type three secretion needle
Nat.Struct.Mol.Biol., 2010
2LPZ
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ATOMIC MODEL OF THE TYPE-III SECRETION SYSTEM NEEDLE
Descriptor:Protein prgI
Authors:Loquet, A., Sgourakis, N.G., Gupta, R., Giller, K., Riedel, D., Goosmann, C., Griesinger, C., Kolbe, M.G., Baker, D., Becker, S., Lange, A.
Deposit date:2012-02-21
Release date:2012-05-16
Last modified:2012-06-27
Method:SOLID-STATE NMR
Cite:Atomic model of the type III secretion system needle.
Nature, 486, 2012
2MEX
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STRUCTURE OF THE TETRAMERIC BUILDING BLOCK OF THE SALMONELLA TYPHIMURIUM PRGI TYPE THREE SECRETION SYSTEM NEEDLE
Descriptor:Protein PrgI
Authors:Loquet, A., Habenstein, B., Chevelkov, V., Giller, K., Becker, S., Lange, A.
Deposit date:2013-10-01
Release date:2013-12-25
Last modified:2014-01-15
Method:SOLID-STATE NMR
Cite:Atomic structure and handedness of the building block of a biological assembly.
J.Am.Chem.Soc., 135, 2013
2MME
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HYBRID STRUCTURE OF THE SHIGELLA FLEXNERI MXIH TYPE THREE SECRETION SYSTEM NEEDLE
Descriptor:MxiH
Authors:Demers, J.P., Habenstein, B., Loquet, A., Vasa, S.K., Becker, S., Baker, D., Lange, A., Sgourakis, N.G.
Deposit date:2014-03-14
Release date:2014-10-08
Method:SOLID-STATE NMR (7.7 Å), ELECTRON MICROSCOPY
Cite:High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy.
Nat Commun, 5, 2014
2MSG
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SOLID-STATE NMR STRUCTURE OF UBIQUITIN
Descriptor:Ubiquitin
Authors:Lakomek, N., Habenstein, B., Loquet, A., Shi, C., Giller, K., Wolff, S., Becker, S., Fasshuber, H., Lange, A.
Deposit date:2014-08-04
Release date:2015-02-18
Last modified:2015-05-13
Method:SOLID-STATE NMR
Cite:Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR.
Protein Sci., 24, 2015
2N7H
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HYBRID STRUCTURE OF THE TYPE 1 PILUS OF UROPATHOGENIC E.COLI
Descriptor:FimA
Authors:Habenstein, B., Loquet, A., Giller, K., Vasa, S., Becker, S., Habeck, M., Lange, A.
Deposit date:2015-09-11
Release date:2015-09-23
Last modified:2015-10-14
Method:SOLID-STATE NMR
Cite:Hybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coli.
Angew.Chem.Int.Ed.Engl., 54, 2015
2X9C
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CRYSTAL STRUCTURE OF A SOLUBLE PRGI MUTANT FROM SALMONELLA TYPHIMURIUM
Descriptor:PROTEIN PRGI
Authors:Poyraz, O., Schmidt, H., Seidel, K., Delissen, F., Ader, C., Tenenboim, H., Goosmann, C., Laube, B., Thuenemann, A.F., Zychlinsky, A., Baldus, M., Lange, A., Griesinger, C., Kolbe, M.
Deposit date:2010-03-15
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Protein Refolding is Required for Assembly of the Type Three Secretion Needle
Nat.Struct.Mol.Biol., 17, 2010
2RNM
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STRUCTURE OF THE HET-S(218-289) PRION IN ITS AMYLOID FORM OBTAINED BY SOLID-STATE NMR
Descriptor:Small s protein
Authors:Wasmer, C., Lange, A., Van Melckebeke, H., Siemer, A., Riek, R., Meier, B.H.
Deposit date:2008-01-24
Release date:2008-04-01
Last modified:2015-07-08
Method:SOLUTION NMR
Cite:Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core
Science, 319, 2008
1UN0
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CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN COMPLEX WITH A NUP2P N-TERMINAL FRAGMENT
Descriptor:IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2
Authors:Matsuura, Y., Lange, A., Harreman, M.T., Corbett, A.H., Stewart, M.
Deposit date:2003-09-03
Release date:2003-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Nup2P Function in Cargo Release and Karyopherin Recycling in Nuclear Import
Embo J., 22, 2003
2N3D
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ATOMIC STRUCTURE OF THE CYTOSKELETAL BACTOFILIN BACA REVEALED BY SOLID-STATE NMR
Descriptor:Bactofilin A
Authors:Shi, C., Fricke, P., Lin, L., Chevelkov, V., Wegstroth, M., Giller, K., Becker, S., Thanbichler, M., Lange, A.
Deposit date:2015-05-29
Release date:2015-12-16
Last modified:2016-02-03
Method:SOLID-STATE NMR
Cite:Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR.
Sci Adv, 1, 2015
2UVS
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HIGH RESOLUTION SOLID-STATE NMR STRUCTURE OF KALIOTOXIN
Descriptor:POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.1
Authors:Korukottu, J., Lange, A., Vijayan, V., Schneider, R., Pongs, O., Becker, S., Baldus, M., Zweckstetter, M.
Deposit date:2007-03-14
Release date:2008-05-27
Last modified:2011-07-13
Method:SOLID-STATE NMR
Cite:Conformational Plasticity in Ion Channel Recognition of a Peptide Toxin
To be Published
3JC8
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ARCHITECTURAL MODEL OF THE TYPE IVA PILUS MACHINE IN A PILIATED STATE
Descriptor:PilA, Type IV-A pilus assembly ATPase PilB, Type 4 fimbrial assembly protein PilC, ...
Authors:Chang, Y.-W., Rettberg, L.A., Jensen, G.J.
Deposit date:2015-11-24
Release date:2016-03-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY
Cite:Architecture of the type IVa pilus machine.
Science, 351, 2016
3JC9
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ARCHITECTURAL MODEL OF THE TYPE IVA PILUS MACHINE IN A NON-PILIATED STATE
Descriptor:PilA, PilC, PilN, ...
Authors:Chang, Y.-W., Rettberg, L.A., Jensen, G.J.
Deposit date:2015-11-24
Release date:2016-03-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY
Cite:Architecture of the type IVa pilus machine.
Science, 351, 2016
3ND2
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STRUCTURE OF YEAST IMPORTIN-BETA (KAP95P)
Descriptor:Importin subunit beta-1
Authors:Forwood, J.K., Kobe, B.
Deposit date:2010-06-06
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Quantitative Structural Analysis of Importin-beta Flexibility: Paradigm for Solenoid Protein Structures
Structure, 18, 2010
2MUS
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HADDOCK CALCULATED MODEL OF LIN5001 BOUND TO THE HET-S AMYLOID
Descriptor:Heterokaryon incompatibility protein s, 3''',4'-bis(carboxymethyl)-2,2':5',2'':5'',2''':5''',2''''-quinquethiophene-5,5''''-dicarboxylic acid
Authors:Hermann, U.S., Schuetz, A.K., Shirani, H., Saban, D., Nuvolone, M., Huang, D.H., Li, B., Ballmer, B., Aslund, A.K.O., Mason, J.J., Rushing, E., Budka, H., Hammarstrom, P., Bockmann, A., Caflisch, A., Meier, B.H., Nilsson, P.K.R., Hornemann, S., Aguzzi, A.
Deposit date:2014-09-16
Release date:2017-02-01
Last modified:2018-06-13
Method:SOLUTION NMR
Cite:Structure-based drug design identifies polythiophenes as antiprion compounds.
Sci Transl Med, 7, 2015