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3USY
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BU of 3usy by Molmil
Crystal structure of Flig (residue 116-343) from H. Pylori
Descriptor: Flagellar motor switch protein
Authors:Lam, K.H, Au, S.W.N.
Deposit date:2011-11-24
Release date:2011-12-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.706 Å)
Cite:Multiple conformations of the FliG C-terminal domain provide insight into flagellar motor switching
Structure, 20, 2012
4FQ0
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BU of 4fq0 by Molmil
Crystal structure of FliG-FliM complex from H. pylori
Descriptor: Flagellar motor switch protein
Authors:Lam, K.H, Au, S.W.N.
Deposit date:2012-06-24
Release date:2013-05-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural basis of FliG-FliM interaction in Helicobacter pylori
Mol.Microbiol., 88, 2013
4GC8
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BU of 4gc8 by Molmil
Crystal structure of FliM middle domain from H. pylori
Descriptor: Flagellar motor switch protein
Authors:Lam, K.H, Au, S.W.N.
Deposit date:2012-07-30
Release date:2013-05-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of FliG-FliM interaction in Helicobacter pylori
Mol.Microbiol., 88, 2013
3GWG
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BU of 3gwg by Molmil
Crystal structure of CheY of Helicobacter pylori
Descriptor: Chemotaxis protein cheY homolog, MAGNESIUM ION, SULFATE ION
Authors:Lam, K.H, Ling, T.K, Au, S.W.
Deposit date:2009-04-01
Release date:2010-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of activated CheY1 from Helicobacter pylori.
J.Bacteriol., 192, 2010
3H1G
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BU of 3h1g by Molmil
Crystal structure of Chey mutant T84A of helicobacter pylori
Descriptor: Chemotaxis protein cheY homolog, MAGNESIUM ION, SULFATE ION
Authors:Lam, K.H, Ling, T.K, Au, S.W.
Deposit date:2009-04-12
Release date:2010-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of activated CheY1 from Helicobacter pylori.
J.Bacteriol., 192, 2010
3H1F
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BU of 3h1f by Molmil
Crystal structure of CheY mutant D53A of Helicobacter pylori
Descriptor: Chemotaxis protein cheY homolog, MAGNESIUM ION, SULFATE ION
Authors:Lam, K.H, Ling, T.K, Au, S.W.
Deposit date:2009-04-12
Release date:2010-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of activated CheY1 from Helicobacter pylori.
J.Bacteriol., 192, 2010
3H1E
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BU of 3h1e by Molmil
Crystal structure of Mg(2+) and BeH(3)(-)-bound CheY of Helicobacter pylori
Descriptor: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein cheY homolog, MAGNESIUM ION, ...
Authors:Lam, K.H, Ling, T.K, Au, S.W.
Deposit date:2009-04-12
Release date:2010-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of activated CheY1 from Helicobacter pylori.
J.Bacteriol., 192, 2010
3USW
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BU of 3usw by Molmil
Crystal structure of FliG (residues 86-343) from H. pylori
Descriptor: Flagellar motor switch protein
Authors:Au, S.W.N, Lam, K.H.
Deposit date:2011-11-24
Release date:2011-12-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Multiple conformations of the FliG C-terminal domain provide insight into flagellar motor switching
Structure, 20, 2012
8FBF
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BU of 8fbf by Molmil
Crystal structure of OrfX2 from Clostridium botulinum E1
Descriptor: Neurotoxin complex component Orf-X2, SULFATE ION
Authors:Lam, K.H, Gao, L.
Deposit date:2022-11-29
Release date:2022-12-21
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of OrfX1, OrfX2 and the OrfX1-OrfX3 complex from the orfX gene cluster of botulinum neurotoxin E1.
Febs Lett., 597, 2023
5XRW
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BU of 5xrw by Molmil
Crystal structure of flagellar motor switch complex from H. pylori
Descriptor: FliN, FliY
Authors:Xue, C, Lam, K.H, Au, S.W.N.
Deposit date:2017-06-10
Release date:2018-06-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three SpoA-domain proteins interact in the creation of the flagellar type III secretion system inHelicobacter pylori.
J.Biol.Chem., 293, 2018
5WUJ
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BU of 5wuj by Molmil
Crystal structure of FliF-FliG complex from H. pylori
Descriptor: Flagellar M-ring protein, Flagellar motor switch protein FliG, GLYCEROL
Authors:Au, S.W, Xue, C, Lam, K.H, Lee, S.H.
Deposit date:2016-12-19
Release date:2017-12-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the FliF-FliG complex from Helicobacter pylori yields insight into the assembly of the motor MS-C ring in the bacterial flagellum
J. Biol. Chem., 293, 2018
2G4D
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BU of 2g4d by Molmil
Crystal structure of human SENP1 mutant (C603S) in complex with SUMO-1
Descriptor: SENP1 protein, Small ubiquitin-related modifier 1
Authors:Xu, Z, Chau, S.F, Lam, K.H, Au, S.W.N.
Deposit date:2006-02-22
Release date:2006-10-17
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the SENP1 mutant C603S-SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease
Biochem.J., 398, 2006
7LZP
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BU of 7lzp by Molmil
LC/A-JPU-B9-JPU-A11-JPU-G11
Descriptor: Botulinum neurotoxin A light chain, JPU-A11, JPU-B9, ...
Authors:Lam, K, Jin, R.
Deposit date:2021-03-10
Release date:2021-12-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
Plos Pathog., 18, 2022
7M1H
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BU of 7m1h by Molmil
Crystal structure of LC/A-JPU-C10-JPU-D12-JPU-B8-JPU-G3-ciA-F12-ciA-D12
Descriptor: Botulinum neurotoxin A light chain, JPU-B8, JPU-C10, ...
Authors:Lam, K, Jin, R.
Deposit date:2021-03-13
Release date:2021-12-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
Plos Pathog., 18, 2022
7NA9
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BU of 7na9 by Molmil
Crystal structure of BoNT/B-LC-JSG-C1
Descriptor: 1,2-ETHANEDIOL, Botulinum neurotoxin type B, JSG-C1, ...
Authors:Lam, K, Jin, R.
Deposit date:2021-06-20
Release date:2021-12-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
Plos Pathog., 18, 2022
6DKK
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BU of 6dkk by Molmil
Structure of BoNT
Descriptor: Botulinum neurotoxin type A, PHOSPHATE ION
Authors:Lam, K, Jin, R.
Deposit date:2018-05-29
Release date:2018-12-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1.
Nat Commun, 9, 2018
7K7Y
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BU of 7k7y by Molmil
Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E9
Descriptor: Botulinum neurotoxin type E, JLE-E9
Authors:Lam, K, Jin, R.
Deposit date:2020-09-24
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells.
Toxins, 12, 2020
7K84
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BU of 7k84 by Molmil
Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E5
Descriptor: Botulinum neurotoxin type E, JLE-E5, SULFATE ION, ...
Authors:Lam, K, Jin, R.
Deposit date:2020-09-25
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells.
Toxins, 12, 2020
7L6V
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BU of 7l6v by Molmil
Crystal structure of BoNT/A-LC-JPU-A5-JPU-C1-JPU-H7-JPU-D12-ciA-F12
Descriptor: 1,2-ETHANEDIOL, BoNT/A, JPU-A5, ...
Authors:Lam, K, Jin, R.
Deposit date:2020-12-24
Release date:2021-12-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
Plos Pathog., 18, 2022
7T5F
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BU of 7t5f by Molmil
Botulinum neurotoxin Type B Light Chain complexed with nanobodies JLJ-G3 and JNE-B10
Descriptor: Botulinum neurotoxin type B, IODIDE ION, JLJ-G3, ...
Authors:Jin, R, Lam, K.-H.
Deposit date:2021-12-12
Release date:2021-12-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
Plos Pathog., 18, 2022
5WIX
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BU of 5wix by Molmil
Crystal structure of P47 of Clostridium botulinum E1
Descriptor: p-47 protein
Authors:Lam, K, Liu, S, Qi, R, Jin, R.
Deposit date:2017-07-20
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein.
Toxicon, 147, 2018
6BVD
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BU of 6bvd by Molmil
Structure of Botulinum Neurotoxin Serotype HA Light Chain
Descriptor: ACETATE ION, CALCIUM ION, Light Chain, ...
Authors:Jin, R, Lam, K.
Deposit date:2017-12-12
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural and biochemical characterization of the protease domain of the mosaic botulinum neurotoxin type HA.
Pathog Dis, 76, 2018
6MHJ
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BU of 6mhj by Molmil
Structure of BoNT mutant
Descriptor: Botulinum neurotoxin type A, PHOSPHATE ION
Authors:Lam, K, Jin, R.
Deposit date:2018-09-18
Release date:2018-12-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.019 Å)
Cite:A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1.
Nat Commun, 9, 2018
5JMC
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BU of 5jmc by Molmil
Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C
Descriptor: Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
5JLV
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BU of 5jlv by Molmil
Receptor binding domain of Botulinum neurotoxin A in complex with human glycosylated SV2C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016

 

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