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1Y98
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BU of 1y98 by Molmil
Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ...
Authors:Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A.
Deposit date:2004-12-14
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex.
Biochemistry, 44, 2005
1QKL
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BU of 1qkl by Molmil
hRPABC14.4, essential subunit of human RNA polymerases I, II and III
Descriptor: DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE
Authors:Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G.
Deposit date:1999-07-26
Release date:1999-11-07
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases
Nat.Struct.Biol., 6, 1999
1GQ4
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BU of 1gq4 by Molmil
STRUCTURAL DETERMINANTS OF THE NHERF INTERACTION WITH BETA2AR AND PDGFR
Descriptor: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50
Authors:Karthikeyan, S, Leung, T, Ladias, J.A.A.
Deposit date:2001-11-19
Release date:2002-05-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors
J.Biol.Chem., 277, 2002
1GQ5
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BU of 1gq5 by Molmil
Structural Determinants of the NHERF Interaction with beta2-AR and PDGFR
Descriptor: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50
Authors:Karthikeyan, S, Leung, T, Ladias, J.A.A.
Deposit date:2001-11-20
Release date:2002-11-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors
J.Biol.Chem., 277, 2002
3BYA
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BU of 3bya by Molmil
Structure of a Calmodulin Complex
Descriptor: CALCIUM ION, Calmodulin, Glutamate [NMDA] receptor subunit zeta-1 peptide
Authors:Birrane, G, Soni, A, Ladias, J.A.A.
Deposit date:2008-01-15
Release date:2009-01-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of a Calmodulin Complex
To be Published
1I92
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BU of 1i92 by Molmil
STRUCTURAL BASIS OF THE NHERF PDZ1-CFTR INTERACTION
Descriptor: CHLORIDE ION, NA+/H+ EXCHANGE REGULATORY CO-FACTOR
Authors:Karthikeyan, S, Leung, T, Ladias, J.A.A.
Deposit date:2001-03-16
Release date:2001-06-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator.
J.Biol.Chem., 276, 2001
2NTE
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BU of 2nte by Molmil
Crystal Structure of the BARD1 BRCT Domains
Descriptor: 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ...
Authors:Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A.
Deposit date:2006-11-07
Release date:2007-06-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the BARD1 BRCT domains.
Biochemistry, 46, 2007
2OEI
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BU of 2oei by Molmil
Crystal structure of human FE65-WW domain in complex with human Mena peptide
Descriptor: Amyloid beta A4 protein-binding family B member 1, poly-proline peptide
Authors:Meiyappan, M, Birrane, G, Ladias, J.A.A.
Deposit date:2006-12-29
Release date:2007-07-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural Basis for Polyproline Recognition by the FE65 WW Domain.
J.Mol.Biol., 372, 2007
3CMY
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BU of 3cmy by Molmil
Structure of a homeodomain in complex with DNA
Descriptor: 1,2-ETHANEDIOL, 5'-D(*DAP*DCP*DAP*DTP*DAP*DAP*DP*DCP*DGP*DAP*DTP*DTP*DAP*DC)-3', 5'-D(*DTP*DGP*DTP*DAP*DAP*DTP*DCP*DGP*DAP*DTP*DTP*DAP*DTP*DG)-3', ...
Authors:Birrane, G, Ladias, J.A.A, Soni, A.
Deposit date:2008-03-24
Release date:2009-02-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for DNA Recognition by the Human PAX3 Homeodomain.
Biochemistry, 48, 2009
4IGK
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BU of 4igk by Molmil
Structure of human BRCA1 BRCT in complex with ATRIP peptide
Descriptor: ATRIP peptide, Breast cancer type 1 susceptibility protein, GLYCEROL
Authors:Liu, X, Ladias, J.A.A.
Deposit date:2012-12-17
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for the BRCA1 BRCT Interaction with the Proteins ATRIP and BAAT1.
Biochemistry, 52, 2013
4IFI
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BU of 4ifi by Molmil
Structure of human BRCA1 BRCT in complex with BAAT peptide
Descriptor: ACETATE ION, BAAT peptide, Breast cancer type 1 susceptibility protein
Authors:Liu, X, Ladias, J.A.A.
Deposit date:2012-12-14
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for the BRCA1 BRCT Interaction with the Proteins ATRIP and BAAT1.
Biochemistry, 52, 2013
1G9O
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BU of 1g9o by Molmil
FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR
Descriptor: NHE-RF
Authors:Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A.
Deposit date:2000-11-26
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains.
J.Mol.Biol., 308, 2001
2I53
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BU of 2i53 by Molmil
Crystal structure of Cyclin K
Descriptor: ACETATE ION, Cyclin K
Authors:Baek, K, Brown, R.S, Birrane, G, Ladias, J.A.A.
Deposit date:2006-08-23
Release date:2007-01-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Human Cyclin K, a Positive Regulator of Cyclin-dependent Kinase 9.
J.Mol.Biol., 366, 2007
2IDH
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BU of 2idh by Molmil
Crystal Structure of human FE65 WW domain
Descriptor: Amyloid beta A4 protein-binding family B member 1, SULFATE ION, TETRAETHYLENE GLYCOL
Authors:Meiyappan, M, Birrane, G, Ladias, J.A.A.
Deposit date:2006-09-15
Release date:2007-07-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural Basis for Polyproline Recognition by the FE65 WW Domain.
J.Mol.Biol., 372, 2007
2ING
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BU of 2ing by Molmil
X-ray Structure of the BRCA1 BRCT mutant M1775K
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Birrane, G, Soni, A, Ladias, J.A.A.
Deposit date:2006-10-07
Release date:2007-09-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Eur.J.Hum.Genet., 16, 2008
2KG2
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BU of 2kg2 by Molmil
Solution structure of a PDZ protein
Descriptor: Tax1-binding protein 3
Authors:Durney, M.A, Birrane, G, Anklin, C, Soni, A, Ladias, J.A.A.
Deposit date:2009-03-02
Release date:2010-01-19
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:Solution structure of the human Tax-interacting protein-1.
J.Biomol.Nmr, 45, 2009

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