Author results

1G9M
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HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, ...
Authors:Kwong, P.D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:2000-11-24
Release date:2000-12-27
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1G9N
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HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, ...
Authors:Kwong, P.D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:2000-11-25
Release date:2000-12-27
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1BUN
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STRUCTURE OF BETA2-BUNGAROTOXIN: POTASSIUM CHANNEL BINDING BY KUNITZ MODULES AND TARGETED PHOSPHOLIPASE ACTION
Descriptor:BETA2-BUNGAROTOXIN, SODIUM ION
Authors:Kwong, P.D., Mcdonald, N.Q., Sigler, P.B., Hendrickson, W.A.
Deposit date:1995-10-15
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of beta 2-bungarotoxin: potassium channel binding by Kunitz modules and targeted phospholipase action.
Structure, 3, 1995
1GC1
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HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY
Descriptor:ENVELOPE PROTEIN GP120, CD4, ANTIBODY 17B, ...
Authors:Kwong, P.D., Wyatt, R., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:1998-06-15
Release date:1998-07-08
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
Nature, 393, 1998
3SE8
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC03 IN COMPLEX WITH HIV-1 GP120
Descriptor:HIV-1 Clade AE strain 93TH057 gp120, Heavy chain of antibody VRC03, Light chain of antibody VRC03, ...
Authors:Kwong, P.D., Zhou, T.
Deposit date:2011-06-10
Release date:2011-08-10
Last modified:2012-08-15
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Science, 333, 2011
3SE9
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY VRC-PG04 IN COMPLEX WITH HIV-1 GP120
Descriptor:HIV-1 Clade AE strain 93TH057 gp120, Heavy chain of antibody VRC-PG04, Light chain of antibody VRC-PG04, ...
Authors:Kwong, P.D., Zhou, T.
Deposit date:2011-06-10
Release date:2011-08-10
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Science, 333, 2011
1RZJ
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HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, ...
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZK
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HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, ...
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
4JPW
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY 12A21 IN COMPLEX WITH HIV-1 STRAIN 93TH057 GP120 MUTANT
Descriptor:HIV-1 CLADE A/E STRAIN 73TH057 GP120 WITH MUTATION H375S, HEAVY CHAIN OF ANTIBODY 12A21, LIGHT CHAIN OF ANTIBODY 12A21, ...
Authors:Acharya, P., Luongo, T., Zhou, T., Kwong, P.D.
Deposit date:2013-03-19
Release date:2013-04-17
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.
Cell(Cambridge,Mass.), 153, 2013
1NCG
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STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Descriptor:N-CADHERIN, YTTERBIUM (III) ION
Authors:Shapiro, L., Fannon, A.M., Kwong, P.D., Thompson, A., Lehmann, M.S., Grubel, G., Legrand, J.-F., Als-Nielsen, J., Colman, D.R., Hendrickson, W.A.
Deposit date:1995-03-23
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995
1NCH
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STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Descriptor:N-CADHERIN, YTTERBIUM (III) ION
Authors:Shapiro, L., Fannon, A.M., Kwong, P.D., Thompson, A., Lehmann, M.S., Grubel, G., Legrand, J.-F., Als-Nielsen, J., Colman, D.R., Hendrickson, W.A.
Deposit date:1995-03-23
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995
1NCI
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STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Descriptor:N-CADHERIN, URANYL (VI) ION
Authors:Shapiro, L., Fannon, A.M., Kwong, P.D., Thompson, A., Lehmann, M.S., Grubel, G., Legrand, J.-F., Als-Nielsen, J., Colman, D.R., Hendrickson, W.A.
Deposit date:1995-03-23
Release date:1995-07-10
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995
1PS5
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STRUCTURE OF THE MONOCLINIC C2 FORM OF HEN EGG-WHITE LYSOZYME AT 2.0 ANGSTROMS RESOLUTION
Descriptor:Lysozyme C, SULFATE ION
Authors:Majeed, S., Ofek, G., Belachew, A., Huang, C., Zhou, T., Kwong, P.D.
Deposit date:2003-06-20
Release date:2003-09-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enhancing Protein Crystallization through Precipitant Synergy
Structure, 11, 2003
1RZ7
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CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 48D
Descriptor:Fab 48d light chain, Fab 48d heavy chain, GLYCEROL
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZ8
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CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B
Descriptor:Fab 17b light chain, Fab 17b heavy chain
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZF
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CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY E51
Descriptor:Fab E51 light chain, Fab E51 heavy chain, GLYCEROL, ...
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZG
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CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120 REACTIVE ANTIBODY 412D
Descriptor:Fab 412d light chain, Fab 412d heavy chain, SUCROSE, ...
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZI
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CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 47E FAB
Descriptor:Fab 47e light chain, Fab 47e heavy chain
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1TJG
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CRYSTAL STRUCTURE OF THE BROADLY NEUTRALIZING ANTI-HIV-1 ANTIBODY 2F5 IN COMPLEX WITH A GP41 7MER EPITOPE
Descriptor:FAB 2F5 Light Chain, FAB 2F5 Heavy Chain, Envelope glycoprotein GP41, ...
Authors:Ofek, G., Tang, M., Sambor, A., Katinger, H., Mascola, J.R., Wyatt, R., Kwong, P.D.
Deposit date:2004-06-04
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanistic analysis of the Anti-Human Immunodeficiency Virus Type 1 antibody 2F5 in complex with its gp41 epitope
J.Virol., 78, 2004
1TJH
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CRYSTAL STRUCTURE OF THE BROADLY NEUTRALIZING ANTI-HIV-1 ANTIBODY 2F5 IN COMPLEX WITH A GP41 11MER EPITOPE
Descriptor:anti-HIV-1 antibody 2F5 Light Chain, anti-HIV-1 antibody 2F5 Heavy Chain, Envelope glycoprotein GP41, ...
Authors:Ofek, G., Tang, M., Sambor, A., Katinger, H., Mascola, J.R., Wyatt, R., Kwong, P.D.
Deposit date:2004-06-04
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
J.Virol., 78, 2004
1TJI
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CRYSTAL STRUCTURE OF THE BROADLY NEUTRALIZING ANTI-HIV-1 ANTIBODY 2F5 IN COMPLEX WITH A GP41 17MER EPITOPE
Descriptor:anti-HIV-1 antibody 2F5 Light Chain, anti-HIV-1 antibody 2F5 Heavy Chain, Envelope Glycoprotein GP41, ...
Authors:Ofek, G., Tang, M., Sambor, A., Katinger, H., Mascola, J.R., Wyatt, R., Kwong, P.D.
Deposit date:2004-06-04
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and mechanistic analysis of the Anti-Human Immunodeficiency Virus type 1 antibody 2F5 in complex with its gp41 epitope
J.Virol., 78, 2004
1WIO
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TETRAGONAL CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1WIP
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, MONOCLINIC CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1WIQ
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TRIGONAL CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1YYL
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CRYSTAL STRUCTURE OF CD4M33, A SCORPION-TOXIN MIMIC OF CD4, IN COMPLEX WITH HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN AND ANTI-HIV-1 ANTIBODY 17B
Descriptor:Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120), antibody 17b light chain, antibody 17b heavy chain, ...
Authors:Huang, C.C., Stricher, F., Martin, L., Decker, J.M., Majeed, S., Barthe, P., Hendrickson, W.A., Robinson, J., Roumestand, C., Sodroski, J., Wyatt, R., Shaw, G.M., Vita, C., Kwong, P.D.
Deposit date:2005-02-25
Release date:2005-05-03
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.
Structure, 13, 2005