Author results

1QHM
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ESCHERICHIA COLI PYRUVATE FORMATE LYASE LARGE DOMAIN
分子名称:PYRUVATE FORMATE-LYASE
著者Leppanen, V.-M., Merckel, M.C., Ollis, D.L., Wong, K.K., Kozarich, J.W., Goldman, A.
登録日1999-05-19
公開日2000-05-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase.
Structure Fold.Des., 7, 1999
1JOF
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NEUROSPORA CRASSA 3-CARBOXY-CIS,CIS-MUCOANTE LACTONIZING ENZYME
分子名称:CARBOXY-CIS,CIS-MUCONATE CYCLASE, SULFATE ION, BETA-MERCAPTOETHANOL, ...
著者Kajander, T., Merckel, M.C., Thompson, A., Deacon, A.M., Mazur, P., Kozarich, J.W., Goldman, A.
登録日2001-07-28
公開日2002-04-12
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of Neurospora crassa 3-carboxy-cis,cis-muconate lactonizing enzyme, a beta propeller cycloisomerase.
Structure, 10, 2002
1MDR
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THE ROLE OF LYSINE 166 IN THE MECHANISM OF MANDELATE RACEMASE FROM PSEUDOMONAS PUTIDA: MECHANISTIC AND CRYSTALLOGRAPHIC EVIDENCE FOR STEREOSPECIFIC ALKYLATION BY (R)-ALPHA-PHENYLGLYCIDATE
分子名称:MANDELATE RACEMASE, MAGNESIUM ION, ATROLACTIC ACID (2-PHENYL-LACTIC ACID)
著者Landro, J.A., Gerlt, J.A., Kozarich, J.W., Koo, C.W., Shah, V.J., Kenyon, G.L., Neidhart, D.J., Fujita, S., Petsko, G.A.
登録日1993-11-19
公開日1994-08-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The role of lysine 166 in the mechanism of mandelate racemase from Pseudomonas putida: mechanistic and crystallographic evidence for stereospecific alkylation by (R)-alpha-phenylglycidate.
Biochemistry, 33, 1994
1MNS
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ON THE ROLE OF LYSINE 166 IN THE MECHANISM OF MANDELATE RACEMASE FROM PSEUDOMONAS PUTIDA: MECHANISTIC AND CRYSTALLOGRAPHIC EVIDENCE FOR STEREOSPECIFIC ALKYLATION BY (R)-ALPHA-PHENYLGLYCIDATE
分子名称:MANDELATE RACEMASE, MAGNESIUM ION, ATROLACTIC ACID (2-PHENYL-LACTIC ACID)
著者Neidhart, D.J., Landro, J.A., Kozarich, J.W.
登録日1993-07-06
公開日1993-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The role of lysine 166 in the mechanism of mandelate racemase from Pseudomonas putida: mechanistic and crystallographic evidence for stereospecific alkylation by (R)-alpha-phenylglycidate.
Biochemistry, 33, 1994
1MZO
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CRYSTAL STRUCTURE OF PYRUVATE FORMATE-LYASE WITH PYRUVATE
分子名称:Pyruvate formate-lyase, TRIETHYLENE GLYCOL, PYRUVIC ACID
著者Lehtio, L., Leppanen, V.-M., Kozarich, J.W., Goldman, A.
登録日2002-10-09
公開日2002-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of Escherichia coli pyruvate formate-lyase with pyruvate.
Acta Crystallogr.,Sect.D, 58, 2002
1RE5
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CRYSTAL STRUCTURE OF 3-CARBOXY-CIS,CIS-MUCONATE LACTONIZING ENZYME FROM PSEUDOMONAS PUTIDA
分子名称:3-carboxy-cis,cis-muconate cycloisomerase, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CITRIC ACID
著者Yang, J., Wang, Y., Woolridge, E.M., Petsko, G.A., Kozarich, J.W., Ringe, D.
登録日2003-11-06
公開日2004-06-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of 3-Carboxy-cis,cis-muconate Lactonizing Enzyme from Pseudomonas putida, a Fumarase Class II Type Cycloisomerase: Enzyme Evolution in Parallel Pathways.
Biochemistry, 43, 2004
1A8T
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METALLO-BETA-LACTAMASE IN COMPLEX WITH L-159,061
分子名称:METALLO-BETA-LACTAMASE, ZINC ION, 2-BUTYL-6-HYDROXY-3-[2'-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-3H-QUINAZOLIN-4-ONE
著者Fitzgerald, P.M.D., Toney, J.H., Grover, N., Vanderwall, D.
登録日1998-03-23
公開日1998-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-beta-lactamase.
Chem.Biol., 5, 1998
1DTN
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MANDELATE RACEMASE MUTANT D270N CO-CRYSTALLIZED WITH (S)-ATROLACTATE
分子名称:MANDELATE RACEMASE, MAGNESIUM ION, ATROLACTIC ACID (2-PHENYL-LACTIC ACID)
著者Clifton, J.G., Petsko, G.A.
登録日1996-03-28
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of the reaction catalyzed by mandelate racemase: importance of electrophilic catalysis by glutamic acid 317.
Biochemistry, 34, 1995
1MDL
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MANDELATE RACEMASE MUTANT K166R CO-CRYSTALLIZED WITH (R)-MANDELATE
分子名称:MANDELATE RACEMASE, MAGNESIUM ION, (R)-MANDELIC ACID, ...
著者Clifton, J.G., Petsko, G.A.
登録日1996-03-29
公開日1996-10-14
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the K166R mutant.
Biochemistry, 34, 1995
1MRA
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MANDELATE RACEMASE MUTANT D270N CO-CRYSTALLIZED WITH (S)-ATROLACTATE
分子名称:MANDELATE RACEMASE, MAGNESIUM ION, ATROLACTIC ACID (2-PHENYL-LACTIC ACID)
著者Clifton, J.G., Petsko, G.A.
登録日1996-03-12
公開日1996-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the D270N mutant.
Biochemistry, 35, 1996
4L7F
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CO-CRYSTAL STRUCTURE OF JNK1 AND AX13587
分子名称:Mitogen-activated protein kinase 8, N-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide
著者Walter, R.L., Ranieri, G.M., Riggs, A.M., Weissig, H., Li, B., Shreder, K.R.
登録日2013-06-13
公開日2013-08-21
最終更新日2013-10-09
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Hit-to-lead optimization and kinase selectivity of imidazo[1,2-a]quinoxalin-4-amine derived JNK1 inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013