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2KZG
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BU of 2kzg by Molmil
A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution
Descriptor: Pre-mRNA-processing factor 40 homolog A
Authors:Korzhnev, D.M, Religa, T.L, Banachewicz, W, Fersht, A.R, Kay, L.E.
Deposit date:2010-06-17
Release date:2010-09-29
Last modified:2014-01-01
Method:SOLUTION NMR
Cite:A transient and low-populated protein-folding intermediate at atomic resolution.
Science, 329, 2010
2L9V
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BU of 2l9v by Molmil
NMR structure of the FF domain L24A mutant's folding transition state
Descriptor: Pre-mRNA-processing factor 40 homolog A
Authors:Korzhnev, D.M, Vernon, R.M, Religa, T.L, Hansen, A, Baker, D, Fersht, A.R, Kay, L.E.
Deposit date:2011-02-24
Release date:2011-09-28
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:Nonnative interactions in the FF domain folding pathway from an atomic resolution structure of a sparsely populated intermediate: an NMR relaxation dispersion study.
J.Am.Chem.Soc., 133, 2011
6WS5
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BU of 6ws5 by Molmil
Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT
Descriptor: 3-[(Z)-(2,3-difluorophenyl)diazenyl]pyridine-2,6-diamine, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ...
Authors:McPherson, K.S, Korzhnev, D.M.
Deposit date:2020-04-30
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.472 Å)
Cite:Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
Chemmedchem, 16, 2021
6WS0
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BU of 6ws0 by Molmil
Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT
Descriptor: DNA polymerase zeta catalytic subunit, DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B
Authors:McPherson, K.S, Korzhnev, D.M.
Deposit date:2020-04-30
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
Chemmedchem, 16, 2021
2LKS
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BU of 2lks by Molmil
Ff11-60
Descriptor: Pre-mRNA-processing factor 40 homolog A
Authors:Barette, J, Velyvis, A, Religa, T.L, Korzhnev, D.M, Kay, L.E.
Deposit date:2011-10-19
Release date:2012-01-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Cross-Validation of the Structure of a Transiently Formed and Low Populated FF Domain Folding Intermediate Determined by Relaxation Dispersion NMR and CS-Rosetta.
J.Phys.Chem.B, 116, 2012
6BCD
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BU of 6bcd by Molmil
Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014)
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
Deposit date:2017-10-20
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BC8
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BU of 6bc8 by Molmil
Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex
Descriptor: ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ...
Authors:Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
Deposit date:2017-10-20
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BI7
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BU of 6bi7 by Molmil
Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y.
Deposit date:2017-11-01
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1RQU
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BU of 1rqu by Molmil
NMR structure of L7 dimer from E.coli
Descriptor: 50S ribosomal protein L7/L12
Authors:Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
Deposit date:2003-12-07
Release date:2004-03-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:From structure and dynamics of protein L7/L12 to molecular switching in ribosome.
J.Biol.Chem., 279, 2004
1RQS
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BU of 1rqs by Molmil
NMR structure of C-terminal domain of ribosomal protein L7 from E.coli
Descriptor: 50S ribosomal protein L7/L12
Authors:Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
Deposit date:2003-12-07
Release date:2004-03-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:From structure and dynamics of protein L7/L12 to molecular switching in ribosome.
J.Biol.Chem., 279, 2004
1RQT
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BU of 1rqt by Molmil
NMR structure of dimeric N-terminal domain of ribosomal protein L7 from E.coli
Descriptor: 50S ribosomal protein L7/L12
Authors:Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
Deposit date:2003-12-07
Release date:2004-03-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:From structure and dynamics of protein L7/L12 to molecular switching in ribosome.
J.Biol.Chem., 279, 2004
1RQV
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BU of 1rqv by Molmil
Spatial model of L7 dimer from E.coli with one hinge region in helical state
Descriptor: 50S ribosomal protein L7/L12
Authors:Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
Deposit date:2003-12-07
Release date:2004-03-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:From structure and dynamics of protein L7/L12 to molecular switching in ribosome
J.Biol.Chem., 279, 2004
2M85
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BU of 2m85 by Molmil
PHD Domain from Human SHPRH
Descriptor: E3 ubiquitin-protein ligase SHPRH, ZINC ION
Authors:Machado, L.E.S.F, Pustovalova, Y, Pozhidaeva, A, Almeida, F.C.L, Bezsonova, I, Korzhnev, D.M.
Deposit date:2013-05-07
Release date:2013-08-14
Last modified:2013-09-11
Method:SOLUTION NMR
Cite:PHD domain from human SHPRH.
J.Biomol.Nmr, 56, 2013
2M2I
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BU of 2m2i by Molmil
NMR solution structure of BRCT domain of yeast REV1
Descriptor: DNA repair protein REV1
Authors:Pustovalova, Y, Maciejewski, M.W, Korzhnev, D.M.
Deposit date:2012-12-21
Release date:2013-01-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR mapping of PCNA interaction with translesion synthesis DNA polymerase Rev1 mediated by Rev1-BRCT domain.
J.Mol.Biol., 425, 2013
2MRE
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BU of 2mre by Molmil
NMR structure of the Rad18-UBZ/ubiquitin complex
Descriptor: E3 ubiquitin-protein ligase RAD18, Polyubiquitin-C, ZINC ION
Authors:Rizzo, A.A, Salerno, P.E, Bezsonova, I, Korzhnev, D.M.
Deposit date:2014-07-03
Release date:2014-10-22
Last modified:2014-10-29
Method:SOLUTION NMR
Cite:NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response.
Biochemistry, 53, 2014
2MRF
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BU of 2mrf by Molmil
NMR structure of the ubiquitin-binding zinc finger (UBZ) domain from human Rad18
Descriptor: E3 ubiquitin-protein ligase RAD18, ZINC ION
Authors:Rizzo, A.A, Salerno, P.E, Bezsonova, I, Korzhnev, D.M.
Deposit date:2014-07-03
Release date:2014-10-01
Last modified:2014-10-08
Method:SOLUTION NMR
Cite:NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response.
Biochemistry, 53, 2014
4S0N
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BU of 4s0n by Molmil
Crystal Structure of HLTF HIRAN Domain bound to DNA
Descriptor: 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', GLYCEROL, Helicase-like transcription factor, ...
Authors:Chavez, D.A, Eichman, B.F.
Deposit date:2015-01-02
Release date:2015-05-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.
Mol.Cell, 58, 2015
8EPT
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BU of 8ept by Molmil
UBE3A isoform 2 AZUL domain
Descriptor: Ubiquitin-protein ligase E3A, ZINC ION
Authors:Bregnard, T.A, Bezsonova, I.
Deposit date:2022-10-06
Release date:2023-07-05
Method:SOLUTION NMR
Cite:Differences in structure, dynamics and Zn-coordination between isoforms of human ubiquitin ligase UBE3A
To Be Published
8ENP
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BU of 8enp by Molmil
UBE3A isoform 3 AZUL
Descriptor: Isoform III of Ubiquitin-protein ligase E3A, ZINC ION
Authors:Bregnard, T.A, Bezsonova, I.
Deposit date:2022-09-30
Release date:2023-10-18
Method:SOLUTION NMR
Cite:Differences in structure, dynamics and Zn-coordination between isoforms of human ubiquitin ligase UBE3A
To Be Published
2LSK
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BU of 2lsk by Molmil
C-terminal domain of human REV1 in complex with DNA-polymerase H (eta)
Descriptor: DNA polymerase eta, DNA repair protein REV1
Authors:Pozhidaeva, A, Pustovalova, Y, Bezsonova, I, Korzhnev, D.
Deposit date:2012-05-01
Release date:2012-06-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase eta.
Biochemistry, 51, 2012
2LSY
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BU of 2lsy by Molmil
Structure of the C-terminal domain from human REV1
Descriptor: DNA repair protein REV1
Authors:Pozhidaeva, A, Pustovalova, Y, Bezsonova, I, Korzhnev, D.
Deposit date:2012-05-09
Release date:2012-06-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase eta.
Biochemistry, 51, 2012
2MZN
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BU of 2mzn by Molmil
NMR structure of the HLTF HIRAN domain in its DNA-bound conformation
Descriptor: Helicase-like transcription factor
Authors:Korzhnev, D, Eldirany, S.
Deposit date:2015-02-18
Release date:2015-07-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.
Mol.Cell, 58, 2015
2N1G
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BU of 2n1g by Molmil
Structure of C-terminal domain of human polymerase Rev1 in complex with PolD3 RIR-motif
Descriptor: DNA polymerase delta subunit 3, DNA repair protein REV1
Authors:Pustovalova, Y, Korzhnev, D.
Deposit date:2015-04-01
Release date:2016-04-13
Last modified:2016-04-20
Method:SOLUTION NMR
Cite:Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Pol zeta Suggests a Mechanism of Polymerase Exchange upon Rev1/Pol zeta-Dependent Translesion Synthesis.
Biochemistry, 55, 2016
2QNJ
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BU of 2qnj by Molmil
Kinase and Ubiquitin-associated domains of MARK3/Par-1
Descriptor: MAP/microtubule affinity-regulating kinase 3
Authors:Murphy, J.M, Ceccarelli, D.F.J, Sicheri, F, Pawson, T.
Deposit date:2007-07-18
Release date:2007-09-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain
Proc.Natl.Acad.Sci.Usa, 104, 2007

217705

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