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5SVA
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BU of 5sva by Molmil
Mediator-RNA Polymerase II Pre-Initiation Complex
Descriptor: 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ...
Authors:Robinson, P.J, Bushnell, D.A, Kornberg, R.D.
Deposit date:2016-08-05
Release date:2016-09-28
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (15.3 Å)
Cite:Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell, 166, 2016
8IFG
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BU of 8ifg by Molmil
Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe
Descriptor: Chromatin modification-related protein eaf3, Cph1, Cph2, ...
Authors:Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D.
Deposit date:2023-02-17
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Class I histone deacetylase complex: Structure and functional correlates.
Proc Natl Acad Sci U S A, 120, 2023
2YU9
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BU of 2yu9 by Molmil
RNA polymerase II elongation complex in 150 mm MG+2 with UTP
Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
Authors:Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
Deposit date:2007-04-06
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
Cell(Cambridge,Mass.), 127, 2006
6XP5
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BU of 6xp5 by Molmil
Head-Middle module of Mediator
Descriptor: HEAT, Med22, Mediator of RNA polymerase II transcription subunit 1, ...
Authors:Zhang, H.Q, Chen, D.C, Kornberg, R.D.
Deposit date:2020-07-08
Release date:2021-03-03
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mediator structure and conformation change.
Mol.Cell, 81, 2021
1I6H
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BU of 1i6h by Molmil
RNA POLYMERASE II ELONGATION COMPLEX
Descriptor: 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ...
Authors:Gnatt, A.L, Cramer, P, Kornberg, R.D.
Deposit date:2001-03-02
Release date:2001-04-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
Science, 292, 2001
5FMF
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BU of 5fmf by Molmil
the P-lobe of RNA polymerase II pre-initiation complex
Descriptor: DNA REPAIR HELICASE RAD25, SSL2, DNA REPAIR HELICASE RAD3, ...
Authors:Murakami, K, Tsai, K, Kalisman, N, Bushnell, D.A, Asturias, F.J, Kornberg, R.D.
Deposit date:2015-11-03
Release date:2015-11-25
Last modified:2017-07-12
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of an RNA Polymerase II Pre-Initiation Complex
Proc.Natl.Acad.Sci.USA, 112, 2015
2E2J
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BU of 2e2j by Molmil
RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP
Descriptor: 27-MER DNA template strand, 5'-D(P*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*A)-3', 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3', ...
Authors:Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2E2H
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BU of 2e2h by Molmil
RNA polymerase II elongation complex at 5 mM Mg2+ with GTP
Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
Authors:Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2E2I
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BU of 2e2i by Molmil
RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ...
Authors:Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
1K83
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BU of 1k83 by Molmil
Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin
Descriptor: ALPHA AMANITIN, DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, ...
Authors:Bushnell, D.A, Cramer, P, Kornberg, R.D.
Deposit date:2001-10-22
Release date:2002-02-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Transcription: Alpha-Amanitin-RNA Polymerase II Cocrystal at 2.8 A Resolution.
Proc.Natl.Acad.Sci.USA, 99, 2002
1NIK
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BU of 1nik by Molmil
Wild Type RNA Polymerase II
Descriptor: DNA-directed RNA polymerase I, II and III 23 kDa polypeptide, DNA-directed RNA polymerase II, ...
Authors:Bushnell, D.A, Kornberg, R.D.
Deposit date:2002-12-24
Release date:2003-04-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Complete, 12-subunit RNA Polymerase II at 4.1-A resolution: implications for the initiation of transcription.
Proc.Natl.Acad.Sci.USA, 100, 2003
3K7A
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BU of 3k7a by Molmil
Crystal Structure of an RNA polymerase II-TFIIB complex
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Liu, X, Bushnell, D.A, Wang, D, Calero, G, Kornberg, R.D.
Deposit date:2009-10-12
Release date:2009-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism.
Science, 327, 2010
1I3Q
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BU of 1i3q by Molmil
RNA POLYMERASE II CRYSTAL FORM I AT 3.1 A RESOLUTION
Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ...
Authors:Cramer, P, Bushnell, D.A, Kornberg, R.D.
Deposit date:2001-02-15
Release date:2001-04-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science, 292, 2001
1I50
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BU of 1i50 by Molmil
RNA POLYMERASE II CRYSTAL FORM II AT 2.8 A RESOLUTION
Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ...
Authors:Cramer, P, Bushnell, D.A, Kornberg, R.D.
Deposit date:2001-02-23
Release date:2001-04-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science, 292, 2001
7YFN
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BU of 7yfn by Molmil
Core module of the NuA4 complex in S. cerevisiae
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ARP4 isoform 1, Actin, ...
Authors:Ji, L.T, Zhao, L.X, Xu, K, Gao, H.H, Zhou, Y, Kornberg, R.D, Zhang, H.Q.
Deposit date:2022-07-08
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the NuA4 histone acetyltransferase complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
7YFP
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BU of 7yfp by Molmil
The NuA4 histone acetyltransferase complex from S. cerevisiae
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ARP4 isoform 1, Actin, ...
Authors:Ji, L.T, Zhao, L.X, Xu, K, Gao, H.H, Zhou, Y, Kornberg, R.D, Zhang, H.Q.
Deposit date:2022-07-08
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of the NuA4 histone acetyltransferase complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
2NVX
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BU of 2nvx by Molmil
RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP
Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
Authors:Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
Deposit date:2006-11-13
Release date:2006-12-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
4GWP
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BU of 4gwp by Molmil
Structure of the Mediator Head Module from S. cerevisiae
Descriptor: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ...
Authors:Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D.
Deposit date:2012-09-03
Release date:2012-10-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GWQ
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BU of 4gwq by Molmil
Structure of the Mediator Head Module from S. cerevisiae in complex with the carboxy-terminal domain (CTD) of RNA Polymerase II Rpb1 subunit
Descriptor: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, ...
Authors:Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D.
Deposit date:2012-09-03
Release date:2012-10-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II.
Proc.Natl.Acad.Sci.USA, 109, 2012
3RJ1
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BU of 3rj1 by Molmil
Architecture of the Mediator Head module
Descriptor: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ...
Authors:Imasaki, T, Calero, G, Cai, G, Tsai, K.L, Yamada, K, Cardelli, F, Erdjument-Bromage, H, Tempst, P, Berger, I, Kornberg, G.L, Asturias, F.J, Kornberg, R.D, Takagi, Y.
Deposit date:2011-04-14
Release date:2011-07-27
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Architecture of the Mediator head module.
Nature, 475, 2011
1R9T
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BU of 1r9t by Molmil
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MISMATCHED NUCLEOTIDE
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA nontemplate strand, DNA template strand, ...
Authors:Westover, K.D, Bushnell, D.A, Kornberg, R.D.
Deposit date:2003-10-30
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell(Cambridge,Mass.), 119, 2004
1R5U
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BU of 1r5u by Molmil
RNA POLYMERASE II TFIIB COMPLEX
Descriptor: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ...
Authors:Bushnell, D.A, Westover, K.D, Davis, R, Kornberg, R.D.
Deposit date:2003-10-13
Release date:2004-02-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms.
Science, 303, 2004
1R9S
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BU of 1r9s by Molmil
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE
Descriptor: DNA strand, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ...
Authors:Westover, K.D, Bushnell, D.A, Kornberg, R.D.
Deposit date:2003-10-30
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell(Cambridge,Mass.), 119, 2004
1SFO
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BU of 1sfo by Molmil
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX
Descriptor: DNA STRAND, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ...
Authors:Westover, K.D, Bushnell, D.A, Kornberg, R.D.
Deposit date:2004-02-20
Release date:2004-03-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II
Science, 303, 2004
1TBP
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BU of 1tbp by Molmil
CRYSTAL STRUCTURE OF YEAST TATA-BINDING PROTEIN AND MODEL FOR INTERACTION WITH DNA
Descriptor: TATA-BINDING PROTEIN
Authors:Chasman, D.I, Flaherty, K.M, Sharp, P.A, Kornberg, R.D.
Deposit date:1993-08-02
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of yeast TATA-binding protein and model for interaction with DNA.
Proc.Natl.Acad.Sci.USA, 90, 1993

 

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