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3GHG
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BU of 3ghg by Molmil
Crystal Structure of Human Fibrinogen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A knob, B knob, ...
Authors:Doolittle, R.F, Kollman, J.M, Sawaya, M.R, Pandi, L, Riley, M.
Deposit date:2009-03-03
Release date:2009-05-19
Last modified:2023-05-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of human fibrinogen.
Biochemistry, 48, 2009
5U3C
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BU of 5u3c by Molmil
CryoEM structure of the CTP synthase filament at 4.6 Angstrom resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE
Authors:Kollman, J.M, Lynch, E.M.
Deposit date:2016-12-01
Release date:2017-04-26
Last modified:2017-06-21
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Human CTP synthase filament structure reveals the active enzyme conformation.
Nat. Struct. Mol. Biol., 24, 2017
5U6R
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BU of 5u6r by Molmil
E. coli CTP synthase CC mutant filament (product-bound)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE
Authors:Kollman, J.M, Lynch, E.M.
Deposit date:2016-12-08
Release date:2017-04-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Human CTP synthase filament structure reveals the active enzyme conformation.
Nat. Struct. Mol. Biol., 24, 2017
8G8F
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BU of 8g8f by Molmil
Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; extended filament segment reconstruction
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, ...
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-02-17
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
8G9B
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BU of 8g9b by Molmil
Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-02-21
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
8FOZ
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BU of 8foz by Molmil
Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; filament assembly interface reconstruction
Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-01-03
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
8FUZ
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BU of 8fuz by Molmil
Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; filament assembly interface reconstruction
Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-01-18
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
6BQW
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BU of 6bqw by Molmil
AlfA Filament bound to AMPPNP
Descriptor: Bacterial actin AlfA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Usluer, G.D, Kollman, J.M, DiMaio, F.
Deposit date:2017-11-28
Release date:2018-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of the bacterial actin AlfA reveals unique assembly and ATP-binding interactions and the absence of a conserved subdomain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8TRN
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BU of 8trn by Molmil
Actin 1 from T. gondii in filaments bound to MgADP and jasplakinolide
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, Jasplakinolide, ...
Authors:Hvorecny, K.L, Sladewski, T.E, Heaslip, A.T, Kollman, J.M.
Deposit date:2023-08-09
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover.
Nat Commun, 15, 2024
8TRM
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BU of 8trm by Molmil
Actin 1 from T. gondii in filaments bound to MgADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION
Authors:Hvorecny, K.L, Sladewski, T.E, Heaslip, A.T, Kollman, J.M.
Deposit date:2023-08-09
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover.
Nat Commun, 15, 2024
8U7V
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BU of 8u7v by Molmil
Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, interface-centered
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-15
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
8U7M
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BU of 8u7m by Molmil
Human retinal variant phosphomimetic IMPDH1(595)-S477D free octamer bound by GTP, ATP, IMP, and NAD+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-15
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
8U8O
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BU of 8u8o by Molmil
Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, octamer-centered
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, ...
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-18
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
8U7Q
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BU of 8u7q by Molmil
Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, octamer-centered
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-15
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
8U8Y
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BU of 8u8y by Molmil
Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, interface-centered
Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-18
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
7UNG
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BU of 7ung by Molmil
48-nm repeat of the human respiratory doublet microtubule
Descriptor: Cilia- and flagella-associated protein 161, Cilia- and flagella-associated protein 20, Cilia- and flagella-associated protein 45, ...
Authors:Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A.
Deposit date:2022-04-11
Release date:2022-10-05
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UN1
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BU of 7un1 by Molmil
8-nm repeat of the human sperm tip singlet microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A.
Deposit date:2022-04-08
Release date:2022-10-05
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (6 Å)
Cite:SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RKH
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BU of 7rkh by Molmil
Yeast CTP Synthase (URA8) tetramer bound to ATP/UTP at neutral pH
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, MAGNESIUM ION, ...
Authors:Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M.
Deposit date:2021-07-22
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Elife, 10, 2021
7RMV
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BU of 7rmv by Molmil
Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, URIDINE 5'-TRIPHOSPHATE
Authors:Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M.
Deposit date:2021-07-28
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Elife, 10, 2021
7RMO
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BU of 7rmo by Molmil
Yeast CTP Synthase (Ura7) Bundle bound to Products at low pH
Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE
Authors:Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M.
Deposit date:2021-07-27
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Elife, 10, 2021
7RMK
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BU of 7rmk by Molmil
Yeast CTP Synthase (Ura7) Bundle bound to substrates at low pH
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, URIDINE 5'-TRIPHOSPHATE
Authors:Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M.
Deposit date:2021-07-27
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Elife, 10, 2021
7RNL
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BU of 7rnl by Molmil
Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates
Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M.
Deposit date:2021-07-29
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Elife, 10, 2021
7RL5
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BU of 7rl5 by Molmil
Yeast CTP Synthase (URA8) filament bound to CTP at low pH
Descriptor: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE
Authors:Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M.
Deposit date:2021-07-23
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Elife, 10, 2021
7RMC
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BU of 7rmc by Molmil
Yeast CTP Synthase (Ura7) filament bound to CTP at low pH
Descriptor: CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE
Authors:Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M.
Deposit date:2021-07-27
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Elife, 10, 2021
7RL0
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BU of 7rl0 by Molmil
Yeast CTP Synthase (URA8) Filament bound to ATP/UTP at low pH
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, MAGNESIUM ION, ...
Authors:Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M.
Deposit date:2021-07-22
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Elife, 10, 2021

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PDB entries from 2024-03-27

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