Author results

3QHT
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CRYSTAL STRUCTURE OF THE MONOBODY YSMB-1 BOUND TO YEAST SUMO
Descriptor:Ubiquitin-like protein SMT3, Monobody ySMB-1, GLYCEROL
Authors:Koide, S., Gilbreth, R.N.
Deposit date:2011-01-26
Release date:2011-05-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design.
Proc.Natl.Acad.Sci.USA, 108, 2011
2AF5
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2.5A X-RAY STRUCTURE OF ENGINEERED OSPA PROTEIN
Descriptor:Engineered Outer Surface Protein A (OspA) with the inserted two beta-hairpins
Authors:Makabe, K., Mcelheny, D., Tereshko, V., Hilyard, A., Koide, A., Koide, S.
Deposit date:2005-07-25
Release date:2006-08-01
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2P42
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COMPLEX OF A CAMELID SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A AT 1.8A RESOLUTION: SE3-MONO-2 CRYSTAL FORM WITH THREE SE-MET SITES (M34, M51, M83) IN VHH SCAFFOLD
Descriptor:Ribonuclease pancreatic, ANTIBODY CAB-RN05, MAGNESIUM ION
Authors:Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.
Deposit date:2007-03-11
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P43
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COMPLEX OF A CAMELID SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A AT 1.65A RESOLUTION: SE3-MONO-1 CRYSTAL FORM WITH THREE SE-MET SITES (M34, M51, M83) IN VHH SCAFFOLD
Descriptor:Ribonuclease pancreatic, ANTIBODY CAB-RN05
Authors:Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.
Deposit date:2007-03-11
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P44
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COMPLEX OF A CAMELID SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A AT 1.8A RESOLUTION: SE5A-MONO-1 CRYSTAL FORM WITH FIVE SE-MET SITES (M34, M51, F68M, M83, L86M) IN VHH SCAFFOLD
Descriptor:Ribonuclease pancreatic, ANTIBODY CAB-RN05
Authors:Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.
Deposit date:2007-03-11
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P45
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COMPLEX OF A CAMELID SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A AT 1.1A RESOLUTION: SE5B-ORTHO-1 CRYSTAL FORM WITH FIVE SE-MET SITES (L4M, M34, M51, F68M, M83) IN VHH SCAFFOLD.
Descriptor:Ribonuclease pancreatic, ANTIBODY CAB-RN05, SULFATE ION
Authors:Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.
Deposit date:2007-03-11
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P46
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COMPLEX OF A CAMELID SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A AT 2.5A RESOLUTION: SE5B-ORTHO-2 CRYSTAL FORM WITH FIVE SE-MET SITES (L4M, M34, M51, F68M, M83) IN VHH SCAFFOLD.
Descriptor:Ribonuclease pancreatic, ANTIBODY CAB-RN05, ZINC ION
Authors:Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.
Deposit date:2007-03-11
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P47
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COMPLEX OF A CAMELID SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A AT 2.5A RESOLUTION: SE5B-TRI CRYSTAL FORM WITH FIVE SE-MET SITES (L4M, M34, M51, F68M, M83) IN VHH SCAFFOLD.
Descriptor:Ribonuclease pancreatic, ANTIBODY CAB-RN05
Authors:Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.
Deposit date:2007-03-11
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P48
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COMPLEX OF A CAMELID SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A AT 2.3A RESOLUTION: SE5B-TETRA CRYSTAL FORM WITH FIVE SE-MET SITES (L4M, M34, M51, F68M, M83) IN VHH SCAFFOLD.
Descriptor:Ribonuclease pancreatic, ANTIBODY CAB-RN05, SULFATE ION
Authors:Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.
Deposit date:2007-03-11
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P49
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COMPLEX OF A CAMELID SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A AT 1.4A RESOLUTION: NATIVE MONO_1 CRYSTAL FORM
Descriptor:Ribonuclease pancreatic, ANTIBODY CAB-RN05, PHOSPHATE ION
Authors:Tereshko, V., Uysal, S., Margalef, K., Koide, A., Kossiakoff, A.A., Koide, S.
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
J.Mol.Biol., 373, 2007
2P4A
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X-RAY STRUCTURE OF A CAMELID AFFINITY MATURED SINGLE-DOMAIN VHH ANTIBODY FRAGMENT IN COMPLEX WITH RNASE A
Descriptor:Ribonuclease pancreatic, ANTIBODY CAB-RN05, SULFATE ION
Authors:Tereshko, V., Koide, A., Uysal, S., Koide, S.
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
J.Mol.Biol., 373, 2007
4JQI
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STRUCTURE OF ACTIVE BETA-ARRESTIN1 BOUND TO A G PROTEIN-COUPLED RECEPTOR PHOSPHOPEPTIDE
Descriptor:Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ...
Authors:Shukla, A.K., Manglik, A., Kruse, A.C., Xiao, K., Reis, R.I., Tseng, W.C., Staus, D.P., Hilger, D., Uysal, S., Huang, L.H., Paduch, M., Shukla, P.T., Koide, A., Koide, S., Weis, W.I., Kossiakoff, A.A., Kobilka, B.K., Lefkowitz, R.J.
Deposit date:2013-03-20
Release date:2013-04-17
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Nature, 497, 2013
5A40
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CRYSTAL STRUCTURE OF A DUAL TOPOLOGY FLUORIDE ION CHANNEL.
Descriptor:PUTATIVE FLUORIDE ION TRANSPORTER CRCB, MONOBODIES, MERCURY (II) ION
Authors:Stockbridge, R.B., Kolmakova-Partensky, L., Shane, T., Koide, A., Koide, S., Miller, C., Newstead, S.
Deposit date:2015-06-04
Release date:2015-09-02
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal Structures of a Double-Barrelled Fluoride Ion Channel.
Nature, 525, 2015
5A43
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CRYSTAL STRUCTURE OF A DUAL TOPOLOGY FLUORIDE ION CHANNEL.
Descriptor:PUTATIVE FLUORIDE ION TRANSPORTER CRCB, MONOBODIES, FLUORIDE ION, ...
Authors:Stockbridge, R.B., Kolmakova-Partensky, L., Shane, T., Koide, A., Koide, S., Miller, C., Newstead, S.
Deposit date:2015-06-04
Release date:2015-09-02
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Crystal Structures of a Double-Barrelled Fluoride Ion Channel.
Nature, 525, 2015
5CWU
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CRYSTAL STRUCTURE OF CHAETOMIUM THERMOPHILUM NUP188 TAIL DOMAIN
Descriptor:Nucleoporin NUP188, GLYCEROL
Authors:Stuwe, T., Bley, C.J., Thierbach, K., Petrovic, S., Schilbach, S., Mayo, D.J., Perriches, T., Rundlet, E.J., Jeon, Y.E., Collins, L.N., Lin, D.H., Paduch, M., Koide, A., Lu, V., Fischer, J., Hurt, E., Koide, S., Kossiakoff, A.A., Hoelz, A.
Deposit date:2015-07-28
Release date:2015-09-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
5CWV
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CRYSTAL STRUCTURE OF CHAETOMIUM THERMOPHILUM NUP192 TAIL DOMAIN
Descriptor:Nucleoporin NUP192
Authors:Stuwe, T., Bley, C.J., Thierbach, K., Petrovic, S., Schilbach, S., Mayo, D.J., Perriches, T., Rundlet, E.J., Jeon, Y.E., Collins, L.N., Lin, D.H., Paduch, M., Koide, A., Lu, V., Fischer, J., Hurt, E., Koide, S., Kossiakoff, A.A., Hoelz, A.
Deposit date:2015-07-28
Release date:2015-09-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.155 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
5CWW
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CRYSTAL STRUCTURE OF THE CHAETOMIUM THERMOPHILUM HETEROTRIMERIC NUP82 NTD-NUP159 TAIL-NUP145N APD COMPLEX
Descriptor:Nucleoporin NUP145N, Nucleoporin NUP82, Nucleoporin NUP159
Authors:Stuwe, T., Bley, C.J., Thierbach, K., Petrovic, S., Schilbach, S., Mayo, D.J., Perriches, T., Rundlet, E.J., Jeon, Y.E., Collins, L.N., Lin, D.H., Paduch, M., Koide, A., Lu, V., Fischer, J., Hurt, E., Koide, S., Kossiakoff, A.A., Hoelz, A.
Deposit date:2015-07-28
Release date:2015-09-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
2KIR
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SOLUTION STRUCTURE OF A DESIGNER TOXIN, MOKATOXIN-1
Descriptor:Designer toxin
Authors:Biancalana, M., Koide, A., Takacs, Z., Goldstein, S., Koide, S.
Deposit date:2009-05-07
Release date:2009-12-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
Proc.Natl.Acad.Sci.USA, 106, 2009
2OCF
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HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH ESTRADIOL AND THE E2#23 FN3 MONOBODY
Descriptor:Estrogen receptor, Fibronectin, ESTRADIOL
Authors:Rajan, S.S., Kuruvilla, S.M., Sharma, S.K., Kim, Y., Huang, J., Koide, A., Koide, S., Joachimiak, A., Greene, G.L.
Deposit date:2006-12-20
Release date:2007-11-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
3CSB
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CRYSTAL STRUCTURE OF MONOBODY YSX1/MALTOSE BINDING PROTEIN FUSION COMPLEX
Descriptor:Maltose-binding protein Monobody YSX1 Fusion, MANGANESE (II) ION, 1,2-ETHANEDIOL, ...
Authors:Gilbreth, R.N., Koide, S.
Deposit date:2008-04-09
Release date:2008-07-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-Protein Interfaces
J.Mol.Biol., 381, 2008
3CSG
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CRYSTAL STRUCTURE OF MONOBODY YS1(MBP-74)/MALTOSE BINDING PROTEIN FUSION COMPLEX
Descriptor:Maltose-binding protein Monobody YS1 Fusion
Authors:Gilbreth, R.N., Koide, S.
Deposit date:2008-04-09
Release date:2008-07-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-Protein Interfaces
J.Mol.Biol., 381, 2008
2OY7
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THE CRYSTAL STRUCTURE OF OSPA MUTANT
Descriptor:Outer surface protein A
Authors:Makabe, K., Terechko, V., Koide, A., Koide, S.
Deposit date:2007-02-21
Release date:2008-03-04
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Aromatic cross-strand ladders control the structure and stability of beta-rich peptide self-assembly mimics
J.Mol.Biol., 383, 2008
2OY8
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THE CRYSTAL STRUCTURE OF OSPA MUTANT
Descriptor:Outer surface protein A
Authors:Makabe, K., Terechko, V., Koide, A., Koide, S.
Deposit date:2007-02-21
Release date:2008-03-04
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Aromatic cross-strand ladders control the structure and stability of beta-rich peptide self-assembly mimics
J.Mol.Biol., 383, 2008
2QBW
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THE CRYSTAL STRUCTURE OF PDZ-FIBRONECTIN FUSION PROTEIN
Descriptor:PDZ-Fibronectin fusion protein, Polypeptide
Authors:Huang, J., Makabe, K., Koide, A., Koide, S.
Deposit date:2007-06-18
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design of protein function leaps by directed domain interface evolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3CH8
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THE CRYSTAL STRUCTURE OF PDZ-FIBRONECTIN FUSION PROTEIN
Descriptor:fusion protein PDZ-Fibronectin, C-terminal octapeptide from protein ARVCF, MAGNESIUM ION
Authors:Makabe, K., Huang, J., Koide, A., Koide, S.
Deposit date:2008-03-08
Release date:2009-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution.
J.Mol.Biol., 392, 2009
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