Author results

1JEM
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NMR STRUCTURE OF HISTIDINE PHOSPHORYLATED FORM OF THE PHOSPHOCARRIER HISTIDINE CONTAINING PROTEIN FROM BACILLUS SUBTILIS, NMR, 25 STRUCTURES
分子名称:HISTIDINE CONTAINING PROTEIN
著者Jones, B.E., Rajagopal, P., Klevit, R.E.
登録日1997-04-01
公開日1997-07-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis.
Protein Sci., 6, 1997
2HID
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REFINED NMR STRUCTURE OF PHOSPHOCARRIER HISTIDINE CONTAINING PROTEIN FROM BACILLUS SUBTILIS
分子名称:HISTIDINE CONTAINING PROTEIN
著者Jones, B.E., Rajagopal, P., Klevit, R.E.
登録日1996-05-17
公開日1996-11-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis.
Protein Sci., 6, 1997
2N0K
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CHEMICAL SHIFT ASSIGNMENTS AND STRUCTURE OF THE ALPHA-CRYSTALLIN DOMAIN FROM HUMAN, HSPB5
分子名称:Alpha-crystallin B chain
著者Rajagopal, P., Klevit, R.E., Shi, L., Baker, D.
登録日2015-03-09
公開日2015-06-03
最終更新日2017-02-15
実験手法SOLUTION NMR
主引用文献A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis.
Elife, 4, 2015
1ARD
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STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
分子名称:YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
著者Hoffman, R.C., Xu, R.X., Horvath, S.J., Herriott, J.R., Klevit, R.E.
登録日1993-10-01
公開日1994-01-31
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1ARE
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STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
分子名称:YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
著者Hoffman, R.C., Xu, R.X., Horvath, S.J., Herriott, J.R., Klevit, R.E.
登録日1993-10-01
公開日1994-01-31
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1ARF
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STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
分子名称:YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
著者Hoffman, R.C., Xu, R.X., Horvath, S.J., Herriott, J.R., Klevit, R.E.
登録日1993-10-01
公開日1994-01-31
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1PAA
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STRUCTURE OF A HISTIDINE-X4-HISTIDINE ZINC FINGER DOMAIN: INSIGHTS INTO ADR1-UAS1 PROTEIN-DNA RECOGNITION
分子名称:YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
著者Bernstein, B.E., Hoffman, R.C., Horvath, S.J., Herriott, J.R., Klevit, R.E.
登録日1994-07-15
公開日1994-10-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition.
Biochemistry, 33, 1994
2KLR
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SOLID-STATE NMR STRUCTURE OF THE ALPHA-CRYSTALLIN DOMAIN IN ALPHAB-CRYSTALLIN OLIGOMERS
分子名称:Alpha-crystallin B chain
著者Jehle, S., Rajagopal, P., Markovic, S., Bardiaux, B., Kuehne, R., Higman, V.A., Klevit, R.E., van Rossum, B., Oschkinat, H.
登録日2009-07-08
公開日2010-07-07
最終更新日2011-07-13
実験手法SOLID-STATE NMR
主引用文献Solid-state NMR and SAXS studies provide a structural basis for the activation of alphaB-crystallin oligomers.
Nat.Struct.Mol.Biol., 17, 2010
3C5R
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CRYSTAL STRUCTURE OF THE BARD1 ANKYRIN REPEAT DOMAIN AND ITS FUNCTIONAL CONSEQUENCES
分子名称:BRCA1-associated RING domain protein 1
著者Fox III, D., Le Trong, I., Stenkamp, R.E., Klevit, R.E.
登録日2008-02-01
公開日2008-05-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences.
J.Biol.Chem., 283, 2008
3FA2
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CRYSTAL STRUCTURE OF THE BRCA1 ASSOCIATED RING DOMAIN (BARD1) TANDEM BRCT DOMAINS
分子名称:BRCA1-associated RING domain protein 1, PHOSPHATE ION, GLYCEROL
著者Fox III, D., Le Trong, I., Stenkamp, R.E., Klevit, R.E.
登録日2008-11-14
公開日2008-12-23
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the BRCA1 Associated Ring Domain (BARD1) Tandem BRCT Domains
TO BE PUBLISHED
3J07
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MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER
分子名称:Alpha-crystallin B chain
著者Jehle, S., Vollmar, B., Bardiaux, B., Dove, K.K., Rajagopal, P., Gonen, T., Oschkinat, H., Klevit, R.E.
登録日2011-04-27
公開日2016-01-20
最終更新日2019-04-24
実験手法SOLID-STATE NMR (20 Å), SOLUTION SCATTERING, ELECTRON MICROSCOPY
主引用文献N-terminal domain of {alpha}B-crystallin provides a conformational switch for multimerization and structural heterogeneity.
Proc.Natl.Acad.Sci.USA, 108, 2011
4BVU
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STRUCTURE OF SHIGELLA EFFECTOR OSPG IN COMPLEX WITH HOST UBCH5C- UBIQUITIN CONJUGATE
分子名称:PROTEIN KINASE OSPG, UBIQUITIN-CONJUGATING ENZYME E2 D3, UBIQUITIN
著者Pruneda, J.N., LeTrong, I., Stenkamp, R.E., Klevit, R.E., Brzovic, P.S.
登録日2013-06-28
公開日2014-01-29
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis.
Embo J., 33, 2014
1BYY
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SODIUM CHANNEL IIA INACTIVATION GATE
分子名称:PROTEIN (SODIUM CHANNEL ALPHA-SUBUNIT)
著者Rohl, C.A., Boeckman, F.A., Baker, C., Scheuer, T., Catterall, W.A., Klevit, R.E.
登録日1998-10-21
公開日1999-10-29
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the sodium channel inactivation gate.
Biochemistry, 38, 1999
1JM7
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SOLUTION STRUCTURE OF THE BRCA1/BARD1 RING-DOMAIN HETERODIMER
分子名称:BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1, ZINC ION
著者Brzovic, P.S., Rajagopal, P., Hoyt, D.W., King, M.-C., Klevit, R.E.
登録日2001-07-17
公開日2001-10-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
Nat.Struct.Biol., 8, 2001
2CSA
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STRUCTURE OF THE M3 MUSCARINIC ACETYLCHOLINE RECEPTOR BASOLATERAL SORTING SIGNAL
分子名称:Muscarinic acetylcholine receptor M3
著者Iverson, H.A., Fox, D., Nadler, L.S., Klevit, R.E., Nathanson, N.M.
登録日2005-05-21
公開日2005-05-31
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Identification and structural determination of the M3 muscarinic acetylcholine receptor basolateral sorting signal.
J.Biol.Chem., 280, 2005
2FUH
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SOLUTION STRUCTURE OF THE UBCH5C/UB NON-COVALENT COMPLEX
分子名称:Ubiquitin-conjugating enzyme E2 D3, Ubiquitin
著者Brzovic, P.S., Lissounov, A., Hoyt, D.W., Klevit, R.E.
登録日2006-01-26
公開日2006-03-28
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination.
Mol.Cell, 21, 2006
2K31
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SOLUTION STRUCTURE OF CGMP-BINDING GAF DOMAIN OF PHOSPHODIESTERASE 5
分子名称:Phosphodiesterase 5A, cGMP-specific, GUANOSINE-3',5'-MONOPHOSPHATE
著者Heikaus, C.C., Stout, J.R., Sekharan, M.R., Eakin, C.M., Rajagopal, P., Brzovic, P.S., Beavo, J.A., Klevit, R.E.
登録日2008-04-16
公開日2008-06-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: Insights into Nucleotide Selectivity, Dimerization, and cGMP-Dependent Conformational Change.
J.Biol.Chem., 283, 2008
2LPB
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STRUCTURE OF THE COMPLEX OF THE CENTRAL ACTIVATION DOMAIN OF GCN4 BOUND TO THE MEDIATOR CO-ACTIVATOR DOMAIN 1 OF GAL11/MED15
分子名称:Mediator of RNA polymerase II transcription subunit 15, General control protein GCN4
著者Brzovic, P.S., Heikaus, C.C., Kisselev, L., Vernon, R., Herbig, E., Pacheco, D., Warfield, L., Littlefield, P., Baker, D., Klevit, R.E., Hahn, S.
登録日2012-02-07
公開日2012-02-22
実験手法SOLUTION NMR
主引用文献The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Mol.Cell, 44, 2011
2MT6
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SOLUTION STRUCTURE OF THE HUMAN UBIQUITIN CONJUGATING ENZYME UBE2W
分子名称:Ubiquitin-conjugating enzyme E2 W
著者Vittal, V., Shi, L., Wenzel, D.M., Brzovic, P.S., Klevit, R.E.
登録日2014-08-14
公開日2014-11-26
最終更新日2015-01-14
実験手法SOLUTION NMR
主引用文献Intrinsic disorder drives N-terminal ubiquitination by Ube2w.
Nat.Chem.Biol., 11, 2015
2N3J
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SOLUTION STRUCTURE OF THE ALPHA-CRYSTALLIN DOMAIN FROM THE REDOX-SENSITIVE CHAPERONE, HSPB1
分子名称:Heat shock protein beta-1
著者Rajagopal, P., Liu, Y., Shi, L., Klevit, R.E.
登録日2015-06-03
公開日2015-08-19
最終更新日2015-10-14
実験手法SOLUTION NMR
主引用文献Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1.
J.Biomol.Nmr, 63, 2015
3DBA
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CRYSTAL STRUCTURE OF THE CGMP-BOUND GAF A DOMAIN FROM THE PHOTORECEPTOR PHOSPHODIESTERASE 6C
分子名称:Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GUANOSINE-3',5'-MONOPHOSPHATE, GLYCEROL
著者Martinez, S.E., Heikaus, C.C., Klevit, R.E., Beavo, J.A.
登録日2008-05-30
公開日2008-07-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change.
J.Biol.Chem., 283, 2008
3UGB
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UBCH5C~UBIQUITIN CONJUGATE
分子名称:Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-C, GLYCEROL
著者Page, R.C., Pruneda, J.N., Klevit, R.E., Misra, S.
登録日2011-11-02
公開日2012-05-16
最終更新日2012-11-14
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
4QPL
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CRYSTAL STRUCTURE OF RNF146(RING-WWE)/UBCH5A/ISO-ADPR COMPLEX
分子名称:E3 ubiquitin-protein ligase RNF146, Ubiquitin-conjugating enzyme E2 D1, 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate), ...
著者Wang, Z., DaRosa, P.A., Klevit, R.E., Xu, W.
登録日2014-06-23
公開日2014-10-15
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.
Nature, 517, 2015
6ALY
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SOLUTION STRUCTURE OF YEAST MED15 ABD2 RESIDUES 277-368
分子名称:Mediator of RNA polymerase II transcription subunit 15
著者Tuttle, L.M., Pacheco, D., Warfield, L., Hahn, S., Klevit, R.E.
登録日2017-08-08
公開日2018-03-21
最終更新日2019-02-20
実験手法SOLUTION NMR
主引用文献Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex.
Cell Rep, 22, 2018
6BP9
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HSPB5 ALPHA-CRYSTALLIN DOMAIN MUTANT R120G-ACD
分子名称:Alpha-crystallin B chain
著者Rajagopal, P., Klevit, R.E.
登録日2017-11-22
公開日2018-11-28
最終更新日2019-02-20
実験手法SOLUTION NMR
主引用文献HSPB5 alpha-crystallin domain mutant R120G-ACD
To Be Published
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